Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anton J. M. de Craen"'
Autor:
Anton J. M. de Craen, Rudi G. J. Westendorp, Karin Hähnel, Henning Zelba, Helene Roelofs, Eline Slagboom, Graham Pawelec, Evelyna Derhovanessian, Andrea B. Maier
Publikováno v:
Age
Age, 35(4), 1387-1399. Springer Netherlands
AGE, 35(4), 1387-1399
Derhovanessian, E, Maier, A B, Hahnel, K, Zelba, H, De Craen, A J M, Roelofs, H, Slagboom, E P, Westendorp, R G J & Pawelec, G 2013, ' Lower proportion of naive peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people ', Age, vol. 35, no. 4, pp. 1387-1399 . https://doi.org/10.1007/s11357-012-9425-7
AGE
AGE; Vol 35
Age, 35(4), 1387-1399. Springer Netherlands
AGE, 35(4), 1387-1399
Derhovanessian, E, Maier, A B, Hahnel, K, Zelba, H, De Craen, A J M, Roelofs, H, Slagboom, E P, Westendorp, R G J & Pawelec, G 2013, ' Lower proportion of naive peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people ', Age, vol. 35, no. 4, pp. 1387-1399 . https://doi.org/10.1007/s11357-012-9425-7
AGE
AGE; Vol 35
The low percentages of naive T cells commonly observed in elderly people are thought to be causally associated with mortality, primarily from infectious disease, and are taken as a hallmark of “immunosenescence”. Whether low levels of naive cells
Autor:
Anton J. M. de Craen, Yvonne M. Drewes, Jacobijn Gussekloo, Wouter de Ruijter, Rudi G. J. Westendorp, Petra G. van Peet
Publikováno v:
Age
AGE
AGE
This study aimed to explore the prognosis of very old people depending on their cardiovascular disease (CVD) history. This observational prospective cohort study included 570 participants aged 85 years from the general population with 5-year follow-u
Autor:
Matt McGue, Anton J. M. de Craen, Rudi G. J. Westendorp, Rabea Kleindorp, James W. Vaupel, Stefan Schreiber, Serena Dato, P. Eline Slagboom, Qihua Tan, Vilhelm A. Bohr, Mikael Thinggaard, Almut Nebel, Marian Beekman, Rune Jacobsen, Mette Soerensen, H. Eka D. Suchiman, Tinna Stevnsner, Lene Christiansen, Kaare Christensen
Publikováno v:
Soerensen, M, Dato, S, Tan, Q, Thinggaard, M, Kleindorp, R, Beekman, M, Suchiman, H E D, Jacobsen, R, McGue, M, Stevnsner, T V, Bohr, V, de Craen, A J M, Westendorp, R G J, Schreiber, S, Slagboom, P E, Nebel, A, Vaupel, J W, Christensen, K & Christiansen, L 2013, ' Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity ', GeroScience, vol. 35, no. 2, pp. 487-500 . https://doi.org/10.1007/s11357-011-9373-7
AGE
Soerensen, M, Dato, S, Tan, Q, Thinggaard, M, Kleindorp, R, Beekman, M, Suchiman, H E D, Jacobsen, R, McGue, M, Stevnsner, T, Bohr, V A, de Craen, A J M, Westendorp, R G J, Schreiber, S, Slagboom, P E, Nebel, A, Vaupel, J W, Christensen, K & Christiansen, L 2013, ' Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity ', Age (Omaha), vol. 35, no. 2, pp. 487-500 . https://doi.org/10.1007/s11357-011-9373-7
AGE
Soerensen, M, Dato, S, Tan, Q, Thinggaard, M, Kleindorp, R, Beekman, M, Suchiman, H E D, Jacobsen, R, McGue, M, Stevnsner, T, Bohr, V A, de Craen, A J M, Westendorp, R G J, Schreiber, S, Slagboom, P E, Nebel, A, Vaupel, J W, Christensen, K & Christiansen, L 2013, ' Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity ', Age (Omaha), vol. 35, no. 2, pp. 487-500 . https://doi.org/10.1007/s11357-011-9373-7
In this study, we investigated 102 single-nucleotide polymorphisms (SNPs) covering the common genetic variation in 16 genes recurrently regarded as candidates for human longevity: APOE; ACE; CETP; HFE; IL6; IL6R; MTHFR; TGFB1; APOA4; APOC3; SIRTs 1,
Autor:
Jeanine J. Houwing-Duistermaat, P. Eline Slagboom, Anton J. M. de Craen, Erik B. van den Akker, Stefan Böhringer, Fernando Rivadeneira, Peter E. Thijssen, Hae-Won Uh, Jelle J. Goeman, André G. Uitterlinden, Marian Beekman, Joris Deelen, Rudi G. J. Westendorp, Ramin Monajemi, Diana van Heemst
Publikováno v:
Age
Journal of the American Aging Association, 35, 1, pp. 235-49
Journal of the American Aging Association, 35, 235-49
AGE; Vol 35
AGE
Age, 35(1), 235-249. Springer International Publishing AG
Age (Dordr)
Journal of the American Aging Association, 35, 1, pp. 235-49
Journal of the American Aging Association, 35, 235-49
AGE; Vol 35
AGE
Age, 35(1), 235-249. Springer International Publishing AG
Age (Dordr)
In genome-wide association studies (GWAS) of complex traits, single SNP analysis is still the most applied approach. However, the identified SNPs have small effects and provide limited biological insight. A more appropriate approach to interpret GWAS
Autor:
Diana van Heemst, Raymond Noordam, David A. Gunn, Christopher E.M. Griffiths, Kelly van Drielen, Rudi G. J. Westendorp, Anton J. M. de Craen
Publikováno v:
Age
AGE, 37(3)
AGE, 37(3)
Circulatory levels of insulin-like growth factor (IGF-1), glucose, and cortisol have been previously associated with facial aging. However, as these serum measures are related, it is unclear whether their associations with skin aging occur independen
Publikováno v:
AGE, 36(3), 1541-1554
In the aging society, it is important to identify very old persons at high risk of functional decline, cardiovascular disease and mortality. However, traditional risk markers lose their predictive value with age. We investigated whether plasma N-term