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Autor:
Elvira Arrizurieta, Gloria Levin, V. De Luca Sarobe, Marta Barontini, Susana Nowicki, Fernando R. Ibarra, Andrea Carranza
Publikováno v:
Acta Physiologica Scandinavica. 185:161-167
Aims: The interplay between natriuretic dopamine and antinatriuretic angiotensin II represents an important mechanism for the regulation of renal sodium and water excretion. Monoamine oxidase is the main metabolizing pathway for dopamine in the renal
Autor:
Michael J. Mulvany, Karin Skov
Publikováno v:
Aarhus University
Renal vascular resistance is increased in essential hypertension, as in genetic models of hypertension. Here we review the evidence that this is at least in part due to structural changes in the afferent arterioles. Rat studies show that the renal af
Autor:
R. M. Nusing, H. W. Seyberth
Publikováno v:
Acta Physiologica Scandinavica. 181:523-528
Hyperprostaglandin E syndrome/antenatal Bartter syndrome is characterized by NaCl wasting and volume depletion, juxtaglomerula hypertrophy, hyperreninism and secondary hyperaldosteronism. Primary causes are mutations in the gene for Na-K-2Cl-cotransp
Publikováno v:
Acta Physiologica Scandinavica. 178:83-89
AIM Dopamine of renal origin reduces tubular sodium reabsorption and controls blood pressure. The present study evaluated renal dopaminergic activity and its response to uninephrectomy in Wistar Han rats from two suppliers, Harlan (W-H) and Charles R
Publikováno v:
Acta Physiologica Scandinavica. 176:91-94
The tubuloglomerular feedback (TGF) mechanism is an important regulator of the glomerular filtration rate (GFR) and urine excretion rate. It operates by sensing the distal delivery of fluid at the macula densa site and adjusting the tone of the glome
Publikováno v:
Acta Physiologica Scandinavica. 175:237-244
Liver cirrhosis is a chronic disease associated with sodium retention due to increased tubular sodium reabsorption. However, the exact tubular site of increased sodium reabsorption in uncertain. We have recently demonstrated selective hypertrophy of
Publikováno v:
Acta Physiologica Scandinavica. 173:343-350
Neonatal inhibition of the renin-angiotensin system [angiotensin-converting enzyme (ACE) inhibition] in the rat results in long-term abnormal renal morphology and function, including interstitial inflammation and fibrosis. Hyaluronan (hyaluronic acid
Publikováno v:
Acta Physiologica Scandinavica. 172:219-226
Dopamine (DA) is an intrarenal natriuretic hormone involved in sodium homeostasis, but the regulation of renal dopaminergic tonus is unclear. We evaluated different pathways for elevating DA tonus to determine which are important for the ability of t
Publikováno v:
Acta Physiologica Scandinavica. 168:233-238
Nitric oxide (NO) and dopamine (DA) have similar effects on renal function, with both having natriuretic and diuretic effects mediated by vascular and tubular mechanisms. Renal ischaemia or hypoxia have been shown to influence the activity of both sy
Publikováno v:
Acta Physiologica Scandinavica. 168:219-223
It is well accepted that dopamine receptors play an important role in the regulation of cardiovascular and kidney function. Most of the knowledge on the renal actions of dopamine has been accumulated focussing on the prototypes of the two known dopam