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pro vyhledávání: '"Philip Van Damme"'
Autor:
Rik Vandenberghe, Philip Van Damme, Evelien Van Schoor, Koen Poesen, Dietmar Rudolf Thal, Lieselot Dedeene
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Motor-, behavior- and/or cognition-related symptoms are key hallmarks in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) with TDP-43 pathology (FTLD-TDP), respectively. It has been reported that these pa
Autor:
Tom Jaspers, Eveliina Pollari, Elisabeth Rossaert, Matthew Jarpe, Ludo Van Den Bosch, Matthieu Moisse, Philip Van Damme, Katrien De Bock, Lawrence Van Helleputte
Publikováno v:
Acta Neuropathologica Communications, 7 (1)
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-19 (2019)
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-19 (2019)
Dysregulation of epigenetic mechanisms is emerging as a central event in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS). In many models of neurodegeneration, global histone acetylation is decreased in the affected neuronal