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of 24
pro vyhledávání: ''
Autor:
Silvia Imre, Adriana Ciurba, Robert-Alexandru Vlad, Paula Antonoaea, Nicoleta Todoran, Daniela Lucia Muntean, Lenard Farczadi, Emoke Redai
Publikováno v:
Acta Medica Marisiensis, Vol 65, Iss 2, Pp 45-48 (2019)
Objectives: The aim of the study was to propose a new UHPLC method for the determination of cannabidiol (CBD) from supplements and drugs available on the Romanian market. Materials and methods: The HPLC assay of CBD was achieved by using a Phenomenex
Autor:
Monica Oroian, Laurian Vlase, Arshad Khuroo, Ravi Kochhar, Ana-Maria Gheldiu, Adriana Marcovici, Diana Ioana Pop, Sandeep Bhardwaj
Publikováno v:
Acta Medica Marisiensis, Vol 64, Iss 4, Pp 161-168 (2018)
Objective: To evaluate the food effect on glicazide disposition in clinical trials conducted on healthy Caucasian volunteers who were given a new modified release oral formulation of Gliclazide 60 mg developed by Sun Pharmaceutical Industries, India.
Publikováno v:
Acta Medica Marisiensis, Vol 64, Iss 3, Pp 111-115 (2018)
Objective: The purpose of this study was to develop a LC-MS method to determine amiodarone (AMI) and its major metabolite desethylamiodarone (DEA) from rat plasma released from the adipose tissue of AMI treated rats subjected to a weight gain/weight
Publikováno v:
Acta Medica Marisiensis, Vol 63, Iss 4, Pp 173-177 (2017)
Objective: This study evaluated the anticonvulsant action of lacosamide (LCS), a novel drug that was recently approved for the treatment of partial or secondarily generalized seizures, using an animal model of generalized epilepsy induced by repetiti
Autor:
Dana Muntean, Corina Briciu, Adina Popa, Maria Neag, Anca Dana Buzoianu, Ana-Maria Gheldiu, Daniel Leucuta, Ioana Todor, Laurian Vlase, Corina Bocsan
Publikováno v:
Acta Medica Marisiensis, Vol 63, Iss 2, Pp 73-79 (2017)
Objective: To analyze a potential phenotypic variation within the studied group based on the pharmacokinetic profile of atomoxetine and its active metabolite, and to further investigate the impact of CYP2D6 phenotype on atomoxetine pharmacokinetics.
Publikováno v:
Acta Medica Marisiensis, Vol 63, Iss 2, Pp 66-69 (2017)
Objective: The study aimed at obtaining and characterizing levofloxacin-loaded, poly(ε-caprolactone) electrospun nanofiber formulations to be used as antibacterial wound dressings. Methods: Drug-loaded nanofibers were obtained by the electrospinning
Publikováno v:
Acta Medica Marisiensis, Vol 63, Iss 1, Pp 36-40 (2017)
Objective: The aim of the study was to compare the influence of mobile phase composition and temperature on chiral separation of racemic ibuprofen by capillary electrophoresis and high performance liquid chromatography with UV detection. Materials an
Autor:
Coman Băbuşanu Anda Cristina, Hăncianu Monica, Agoroaei Luminiţa, Mahu Ştefania Corina, Butnaru Elena
Publikováno v:
Acta Medica Marisiensis, Vol 61, Iss 4, Pp 356-360 (2015)
Arterial hypertension is a complex disease with many serious complications, representing a leading cause of mortality. Selective beta-blockers such as metoprolol and bisoprolol are frequently used in the management of hypertension. Numerous analytica
Publikováno v:
Acta Medica Marisiensis, Vol 61, Iss 3, Pp 196-199 (2015)
Objectives: Venlafaxine is an antidepressant, categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI) with suspected metabolic side effects. The aim of our study was to assess these metabolic effects in rats, using two different doses of
Publikováno v:
Acta Medica Marisiensis, Vol 61, Iss 3, Pp 176-179 (2015)
Introduction: The widespread use of sevoflurane as an induction and maintenance volatile agent of general anesthesia demostrates an increased safety profile. Sevoflurane contact with CO2 absorbents lead to the occurrence of toxic compounds such as Co