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Publikováno v:
Acta histochemica. 123(8)
OBJECTIVE To investigate the effect and potential mechanism of quercetin on inflammation, oxidative stress, apoptosis, and mitochondrial structure and function in H9C2 cells. MATERIALS AND METHODS H9C2 cells were obtained from the Shanghai Institutes
Autor:
Warne Pedro de Andrade, Dawidson Assis Gomes, Luciana Maria Silva, Bryan Ôrtero Perez Gonçalves, Sílvia Ligório Fialho, Gabryella S P Santos
Publikováno v:
Acta histochemica. 123(6)
Despite aggressive therapy, most patients with brain tumors present disease relapse due to the cellular and molecular nature of these tumors. One of the models that best explains the heterogeneity observed in CNS tumors is the presence of cancer stem
Autor:
Klea Ferro, Vashendriya V V Hira, Annique Loncq de Jong, Remco J. Molenaar, Cornelis J.F. Van Noorden, Mohammed Khurshed
Publikováno v:
Acta histochemica, 121(2), 125-134. Urban und Fischer Verlag Jena
Immunohistochemistry (IHC) specifically localizes proteins in cells and tissues, but methodologies vary widely. Therefore, we performed a methodological IHC optimization and validation study. First, we compared advantages and disadvantages of cryosta
Publikováno v:
Acta histochemica. 123(5)
Lappaconitine hydrochloride (LH), as a new synthetic alkaloid, exhibits antitumor activity, whereas its antitumor effect on colorectal cancer (CRC) has not been investigated. In this study, the effect of LH on HCT-116 cell proliferation and apoptosis
Publikováno v:
Acta histochemica. 122(5)
Lappaconitine sulfate (LS) has good solubility and bioavailability. We have previously studied the anti-proliferative activity of LS on colon cancer HT-29 cell, but its anti-proliferative activity and molecular mechanism on human non-small cell lung
Publikováno v:
Acta Histochemica. 120:56-63
Cell migration inducing hyaluronan binding protein (CEMIP) is a hyaluronic acid binding protein, the abnormal elevation of which is suggested as a contributor in the carcinogenesis of colorectal cancer (CRC). Cancer cells lose their adhesive properti
Publikováno v:
Acta Histochemica. 119:337-342
Gastric cancer (GC) is an aggressive disease that remains the fourth most common type of cancer and is the second leading cause of cancer-related death worldwide. Treatment of advanced or metastatic GC has seen little progress and median overall surv
Autor:
Anna Klimaszewska-Wisniewska, Andrzej Pawlik, Lidia Gackowska, Alina Grzanka, Mariusz Andrzej Szczepanski, Agnieszka Zuryń
Publikováno v:
Acta Histochemica. 118:784-796
The aim of this study was to investigate the cytotoxic effect of mitoxantrone on two human non-small cell lung cancer cell lines, A549 (p53+) and H1299 (p53-). To our knowledge, this is the first study to evaluate the impact of MXT on the organizatio
Publikováno v:
Acta Histochemica. 120:151-153
Bronze corydoras (Corydoras aeneus) uses the distal part of the intestine as accessory respiratory organ. Our previous study showed the presence of epidermal growth factor receptor (EGFR) cytoplasmic domain in the digestive tract of the bronze corydo
Autor:
Luca Vanella, Francesco Pepe, Toniangelo Onni, Agata Zappalà, Giovanni Li Volti, Ignazio Barbagallo, Rosalba Parenti, Daniele Tibullo
Publikováno v:
Acta Histochemica. 117:705-711
Heat shock proteins are ubiquitous molecular chaperones involved in post-translational folding, stability, activation and maturation of many proteins that are essential mediators of signal transduction and cell cycle progression. Heat shock protein 9