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Autor:
Nimrod Buchbinder, Hassan Atmani, Jean-Pierre Vannier, Guy Ladam, Sandrine Morin-Grognet, Béatrice Labat
Publikováno v:
Acta Biomaterialia. 135:383-392
Neuroblastoma is the third most common pediatric cancer composed of malignant immature cells that are usually treated pharmacologically by all trans-retinoic acid (ATRA) but sometimes, they can spontaneously differentiate into benign forms. In that c
Autor:
Jianzhong Xu, Rui Zhou, Yueqi Chen, Fei Luo, Moyuan Deng, Zhigang Rong, Keyu Luo, Chen Can, Wenjie Wu, Shiwu Dong, Jiulin Tan, Qijie Dai, Yong Tang, Chengmin Zhang, Xueke Yu
Publikováno v:
Acta Biomaterialia. 126:183-198
Selective cell retention (SCR) has been widely used as a bone tissue engineering technique for the real-time fabrication of bone grafts. The greater the number of mesenchymal stem cells (MSCs) and endothelial progenitor cells (EPCs) retained in the s
Autor:
Soo-Hong Lee, Byoung Ju Kim, Yoshie Arai, Sunghyun Park, Hyoeun Park, James J. Moon, Bogyu Choi
Publikováno v:
Acta Biomaterialia. 125:219-230
Extracellular matrix (ECM) remodeling is necessary for the development and self-healing of tissue, and the process is tissue specific. Matrix metalloproteinases (MMPs) play a role in ECM remodeling by unwinding and cleaving ECM. We hypothesized that
Autor:
Christopher W. Anderson, Yifan Yuan, Juan Wang, Mehmet H. Kural, Yuyao Lin, Jiesi Luo, Xiangyu Shi, Matthew W. Ellis, Yibing Qyang, Muhammad Riaz, Laura E. Niklason, Shang-Min Zhang
Publikováno v:
Acta Biomater
Tissue engineered vascular grafts (TEVGs) represent a promising therapeutic option for emergency vascular intervention. Although the application of small-diameter TEVGs using patient-specific primary endothelial cells (ECs) to prevent thrombosis and
Publikováno v:
Acta Biomaterialia. 116:162-173
Thermoresponsive surfaces enable the detachment of cells or cell sheets by decreasing the temperature of the surface when harvesting the cells. However, human pluripotent stem cells (hPSCs), such as embryonic stem cells and induced pluripotent stem c
Autor:
Kibret Mequanint, Khalil Dayekh
Publikováno v:
Acta Biomaterialia. 115:288-298
Ectopic vascular calcification associated with aging, diabetes mellitus, atherosclerosis, and chronic kidney disease is a considerable risk factor for cardiovascular events and death. Although vascular smooth muscle cells are primarily implicated in
Publikováno v:
Acta Biomaterialia. 114:158-169
Endochondral ossification (ECO) is an important process of bone tissue development. During ECO, extracellular matrices (ECMs) are essential factors to control cell functions and induce bone regeneration. However, the exact role of ECO ECMs on stem ce
Autor:
Kyle S. Coots, Kevin T. Nella, Christian B. Roque, Hsiang-Tsun Chang, Akihiro J. Matsuoka, Rachel A. Heuer, Tammy L. McGuire, Andrew M. Oleksijew
Publikováno v:
Acta Biomater
Although the application of human embryonic stem cells (hESCs) in stem cell-replacement therapy remains promising, its potential is hindered by a low cell survival rate in post-transplantation within the inner ear. Here, we aim to enhance the in vitr
Autor:
Jingwei Zhang, Davide Barbieri, Dongqin Xiao, Gang Feng, Lorenzo Moroni, Huipin Yuan, Chengdong Zhang
Publikováno v:
Acta Biomaterialia. 106:22-33
Calcium phosphate (CaP) ceramics have been widely used for bone regeneration because of their ability to induce osteogenesis. Surface properties, including chemical composition and surface structure, are known to play a crucial role in osteoconductio
Autor:
Miji Yeo, GeunHyung Kim
Publikováno v:
Acta Biomaterialia. 107:102-114
Human skeletal muscle is composed of intricate anatomical structures, including uniaxially arranged myotubes and widely distributed blood capillaries. In this regard, vascularization is an essential part of the successful development of an engineered