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Autor:
Jianzhong Xu, Rui Zhou, Yueqi Chen, Fei Luo, Moyuan Deng, Zhigang Rong, Keyu Luo, Chen Can, Wenjie Wu, Shiwu Dong, Jiulin Tan, Qijie Dai, Yong Tang, Chengmin Zhang, Xueke Yu
Publikováno v:
Acta Biomaterialia. 126:183-198
Selective cell retention (SCR) has been widely used as a bone tissue engineering technique for the real-time fabrication of bone grafts. The greater the number of mesenchymal stem cells (MSCs) and endothelial progenitor cells (EPCs) retained in the s
Autor:
Soo-Hong Lee, Byoung Ju Kim, Yoshie Arai, Sunghyun Park, Hyoeun Park, James J. Moon, Bogyu Choi
Publikováno v:
Acta Biomaterialia. 125:219-230
Extracellular matrix (ECM) remodeling is necessary for the development and self-healing of tissue, and the process is tissue specific. Matrix metalloproteinases (MMPs) play a role in ECM remodeling by unwinding and cleaving ECM. We hypothesized that
Publikováno v:
Acta Biomaterialia. 116:162-173
Thermoresponsive surfaces enable the detachment of cells or cell sheets by decreasing the temperature of the surface when harvesting the cells. However, human pluripotent stem cells (hPSCs), such as embryonic stem cells and induced pluripotent stem c
Autor:
Kibret Mequanint, Khalil Dayekh
Publikováno v:
Acta Biomaterialia. 115:288-298
Ectopic vascular calcification associated with aging, diabetes mellitus, atherosclerosis, and chronic kidney disease is a considerable risk factor for cardiovascular events and death. Although vascular smooth muscle cells are primarily implicated in
Publikováno v:
Acta Biomater
Cellular attachment and response to biomaterials are mediated by integrin receptor binding to extracellular matrix proteins adsorbed onto the material surface. Osteoblasts interact with their substrates via several integrin complexes including fibron
Publikováno v:
Acta Biomaterialia. 97:399-408
Olfaction is normally taken for granted in our lives, not only assisting us to escape from dangers, but also increasing our quality of life. Although olfactory neuroepithelium (ON) can reconstitute its olfactory receptor neurons (ORNs) after injury,
Publikováno v:
Acta Biomaterialia. 84:194-207
Although adipose tissue is one of the most abundant tissues of the human body, its reconstruction remains a competitive challenge. The conventional in vitro two or three-dimensional (2D or 3D) models of mature adipocytes unfortunately lead to their q
Publikováno v:
Acta Biomaterialia. 68:204-213
Olfactory dysfunction significantly influences patients’ life quality, but currently has no adequate treatment. Poly (ethylene-co-vinyl alcohol) (EVAL) mediates cell adhesion, growth and modulates differentiation of neural stem cells. However, whet
Autor:
Shigang Lin, Kibret Mequanint
Publikováno v:
Acta Biomaterialia. 59:200-209
In vitro maturation of engineered vascular tissues (EVT) requires the appropriate incorporation of smooth muscle cells (SMC) and extracellular matrix (ECM) components similar to native arteries. To this end, the aim of the current study was to fabric
Autor:
Fei Luo, Zhilin Li, Shiwu Dong, Junchao Xing, Tieniu Mei, Zehua Zhang, Jianzhong Xu, Aijun Yang, Zhao Xie, Keyu Luo, Zhiqiang Li, Tianyong Hou
Publikováno v:
Acta Biomaterialia. 53:470-482
Easily accessible and effective bone grafts are in urgent need in clinic. The selective cell retention (SCR) strategy, by which osteogenesis-related cells and factors are enriched from bone marrow into bio-scaffolds, holds great promise. However, the