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Autor:
Jianzhong Xu, Rui Zhou, Yueqi Chen, Fei Luo, Moyuan Deng, Zhigang Rong, Keyu Luo, Chen Can, Wenjie Wu, Shiwu Dong, Jiulin Tan, Qijie Dai, Yong Tang, Chengmin Zhang, Xueke Yu
Publikováno v:
Acta Biomaterialia. 126:183-198
Selective cell retention (SCR) has been widely used as a bone tissue engineering technique for the real-time fabrication of bone grafts. The greater the number of mesenchymal stem cells (MSCs) and endothelial progenitor cells (EPCs) retained in the s
Autor:
Soo-Hong Lee, Byoung Ju Kim, Yoshie Arai, Sunghyun Park, Hyoeun Park, James J. Moon, Bogyu Choi
Publikováno v:
Acta Biomaterialia. 125:219-230
Extracellular matrix (ECM) remodeling is necessary for the development and self-healing of tissue, and the process is tissue specific. Matrix metalloproteinases (MMPs) play a role in ECM remodeling by unwinding and cleaving ECM. We hypothesized that
Publikováno v:
Acta Biomaterialia. 116:162-173
Thermoresponsive surfaces enable the detachment of cells or cell sheets by decreasing the temperature of the surface when harvesting the cells. However, human pluripotent stem cells (hPSCs), such as embryonic stem cells and induced pluripotent stem c
Autor:
Kibret Mequanint, Khalil Dayekh
Publikováno v:
Acta Biomaterialia. 115:288-298
Ectopic vascular calcification associated with aging, diabetes mellitus, atherosclerosis, and chronic kidney disease is a considerable risk factor for cardiovascular events and death. Although vascular smooth muscle cells are primarily implicated in
Autor:
Kyle S. Coots, Kevin T. Nella, Christian B. Roque, Hsiang-Tsun Chang, Akihiro J. Matsuoka, Rachel A. Heuer, Tammy L. McGuire, Andrew M. Oleksijew
Publikováno v:
Acta Biomater
Although the application of human embryonic stem cells (hESCs) in stem cell-replacement therapy remains promising, its potential is hindered by a low cell survival rate in post-transplantation within the inner ear. Here, we aim to enhance the in vitr
Autor:
Julien Guerrero, Denis Dufrane, Qingfeng Li, Kai Liu, Elisabeth A. Kappos, Arnaud Scherberich, Ru-Lin Huang, Alina Samia Senn, Ivan Martin, Dirk J. Schaefer
Publikováno v:
Acta Biomaterialia. 102:458-467
Engineering of materials consisting of hypertrophic cartilage, as physiological template for de novo bone formation through endochondral ossification (ECO), holds promise as a new class of biological bone substitutes. Here, we assessed the efficiency
Publikováno v:
Acta Biomater
Cellular attachment and response to biomaterials are mediated by integrin receptor binding to extracellular matrix proteins adsorbed onto the material surface. Osteoblasts interact with their substrates via several integrin complexes including fibron
Publikováno v:
Acta Biomaterialia. 97:399-408
Olfaction is normally taken for granted in our lives, not only assisting us to escape from dangers, but also increasing our quality of life. Although olfactory neuroepithelium (ON) can reconstitute its olfactory receptor neurons (ORNs) after injury,
Publikováno v:
Acta Biomaterialia. 86:125-134
Formation of the primitive streak (PS) marks one of the most important developmental milestones in embryonic development. However, our understanding of cellular mechanism(s) underlying cell fate diversification along the anterior-posterior axis of th
Publikováno v:
Acta Biomaterialia. 84:194-207
Although adipose tissue is one of the most abundant tissues of the human body, its reconstruction remains a competitive challenge. The conventional in vitro two or three-dimensional (2D or 3D) models of mature adipocytes unfortunately lead to their q