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Publikováno v:
Acta Biochimica et Biophysica Sinica. 47:663-672
The chemokine CXCL12 and its receptor CXCR4 are important signaling components required for human blastocyst implantation and the progression of pregnancy. Growing evidence indicates that the CXCL12/CXCR4 axis can regulate trophoblast function and ut
Publikováno v:
Acta Biochimica et Biophysica Sinica. 45:527-533
Apelin is a bioactive peptide discovered recently that has been proved to be an endogenous ligand of the APJ receptor. Apelin and APJ are widely distributed in the central nervous system and peripheral tissues. Researches have confirmed that apelin/A
Autor:
Xiao-Xu Li, Xiaohui Zha, Zhong-Cheng Mo, Zhi-Sheng Jiang, Xiao-Hua Yu, Chao-Ke Tang, Yuchang Fu, Kai Yin, Ji Xiao, Guo-Jun Zhao
Publikováno v:
Acta Biochimica et Biophysica Sinica. 44:119-128
The Niemann-Pick type C1 (NPC1) is located mainly in the membranes of the late endosome/lysosome and controls the intracellular cholesterol trafficking from the late endosome/lysosome to the plasma membrane. It has been reported that oxidized low-den
Publikováno v:
Acta Biochimica et Biophysica Sinica. 46:620-622
Human ELA consists of three exons on chromosome 4, which generates a transcript (AK092578) that is annotated as a non-coding RNA. However, Chng et al. [1] has found that this gene contains a conserved open reading frame predicted to express a conserv
Publikováno v:
Acta biochimica et biophysica Sinica. 44(11)
Asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor, is considered to be an independent risk factor in the progression of chronic kidney diseases (CKD). It can induce kidney fibrosis by increasing transforming growth fac
Publikováno v:
Acta biochimica et biophysica Sinica. 44(4)
Angiogenesis is crucial in wound healing. The administration of the C-terminal 24-a.a. peptide of mechano growth factor (MGF24E) has been previously demonstrated to induce more blood vessels in regenerating bone around defective areas compared with t