Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ajit Jadhav"'
Autor:
Alexey V. Zakharov, Darrell L. Peterson, Adam Yasgar, Ajit Jadhav, Daniel C. Talley, Rong Huang, Anton Simeonov, Guangping Dong, Ken Chih-Chien Cheng
Publikováno v:
ACS Comb Sci
Methyltransferases (MTases) play diverse roles in cellular processes. Aberrant methylation levels have been implicated in many diseases, indicating the need for the identification and development of small molecule inhibitors for each MTase. Specific
Autor:
Adam Yasgar, David J. Maloney, Leggy A. Arnold, Ganesha Rai, Anton Simeonov, Preetpal S. Sidhu, Ajit Jadhav, Kelly A. Teske, Premchendar Nandhikonda, Belaynesh Feleke
Publikováno v:
ACS Combinatorial Science. 19:646-656
We describe the parallel synthesis of novel analogs of GW0742, a peroxisome proliferator-activated receptor δ (PPARδ) agonist. For that purpose, modified reaction conditions were applied, such as a solid-phase palladium-catalyzed Suzuki coupling. I