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Autor:
Rodrigo F. Ortiz-Meoz, Jiaoyang Jiang, Suzanne Walker, Craig J. Thomas, Marina Orman, John Janetzko, Zhi Wei Tan, Michael B. Lazarus, Chenguang Fan, Damien Y. Duveau
Publikováno v:
ACS chemical biology. 10(6)
O-GlcNAc transferase (OGT) is an essential mammalian enzyme that regulates numerous cellular processes through the attachment of O-linked N-acetylglucosamine (O-GlcNAc) residues to nuclear and cytoplasmic proteins. Its targets include kinases, phosph