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pro vyhledávání: '"Christopher J. Schofield"'
Autor:
Nicolai Lehnert, Rajeev Ramanan, Shobhit S. Chaturvedi, Tatyana G. Karabencheva-Christova, Christo Z. Christov, Christopher J. Schofield, Sodiq O. Waheed
Publikováno v:
ACS Central Science, Vol 6, Iss 5, Pp 795-814 (2020)
ACS Central Science
ACS Central Science
AlkB and its human homologue AlkBH2 are Fe(II)- and 2-oxoglutarate (2OG)-dependent oxygenases that repair alkylated DNA bases occurring as a consequence of reactions with mutagenic agents. We used molecular dynamics (MD) and combined quantum mechanic