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Autor:
Robert Coleman
This book provides a history and discussion of the use of human tissues as an alternative to animal-based testing for assessing the efficacy and safety of new medicines. Beginning by providing a historical background to animal-based testing, this tex
Autor:
E. J. Ariëns
Drug Design, Volume VII covers the design of agents such as blood substitutes, pesticides derived from insect pheromones, and herbicides related to the auxin-type plant hormones. The book discusses the design of artificial blood substitutes and auxin
Autor:
E. J. Ariëns
Drug Design, Volume III covers the mode of action of biologically active compounds. The book discusses microbial transformations that have been used in the preparation of drugs or closely related substances; the use of linear free energy parameters a
Autor:
E. J. Ariëns
Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible