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pro vyhledávání: '"686"'
Autor:
Robert K. Oldham, Robert O. Dillman
At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many
Chemoprevention is currently regarded as one of the most promising avenues for the control of cancer, with human epidemiological and animal studies indicating that the risk of cancer may be modified by changes in diet. Over 100 papers are collected i
The finding that chemicals can be metabolically activated to yield reactive chemical species capable of covalently binding to cellular macromolecules and the concept that these reactions could initiate toxicological and carcinogenic events stimulated
Autor:
Robert R. Snyder, James J. Kocsis, I. Glenn Sipes, George F. Kalf, David J. Jollow, Helmut Greim, Terrence J. Monks, Charlotte M. Witmer
Much of organic chemistry is based on the ability of suitably structured chemicals to bind together through the formation of covalent bonds. Biochemistry is replete with exam ples of enzymatically catalyzed reactions in which normal body constituen
Oxidation-reduction (i.e. redox) processes at the plasma membrane of any cell have been attracting more and more attention, both in basic and in applied research, since the first workshop dealing with the plasma membrane oxidoreductases was organized
Autor:
Alvaro Macieira-Coelho
The problem of the long-term proliferation of cells is a seminal one. It has always been a hot subject in biology, a source of far-reaching hypotheses, even more so now when explanations for the mechanisms of cell prolifera tive mortality or immort
Autor:
John B. Schenkman, Helmut Greim
In this book the editors have brought together the widest group of investigators of the cytochrome P450 superfamily in order to present complete and right up-to-date coverage of this important enzyme system. The authors describe and analyze the compo
While serendipity and random screening continue to fulfil a significant role in the search for new drugs, current remarkable advances in molecular biology and genetics are dictating to a profound extent the approaches employed in their development. I
Autor:
Michael B. Sporn, Anita B. Roberts
This two-volume treatise, the collected effort of more than 50 authors, represents the first comprehensive survey of the chemistry and biology of the set of molecules known as peptide growth factors. Although there have been many symposia on this top