Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Zylka, Mark J."'
Autor:
Jiménez, Jessica A., Ptacek, Travis S., Tuttle, Alex H., Schmid, Ralf S., Moy, Sheryl S., Simon, Jeremy M., Zylka, Mark J.
Additional file 6: Supplemental Information.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bec4428e0fb1254379b0453d14aa031
Autor:
Pinckney, Lennisha, Zylka, Mark J., Paul, Ketema N., Jones, Kelly A., Gray, Cloe L., Ehlen, J. Christopher, Philpot, Benjamin D., Brager, Allison J., DeBruyne, Jason P., Burette, Susan, Weinberg, Richard J., Evans, Jennifer A.
Individuals with Angelman syndrome (AS) suffer sleep disturbances that severely impair quality of life. Whether these disturbances arise from sleep or circadian clock dysfunction is currently unknown. Here, we explored the mechanistic basis for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab392245f5af581004add44465271176
Coordination of membrane deformation and cytoskeletal dynamics lies at the heart of many biological processes critical for cell polarity, motility and morphogenesis. We have recently shown that Slit-Robo GTPase-activating protein 2 (srGAP2) regulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a76e4cf4d4e61950f5c4eeaa4a2bbfc
Autor:
Korboukh, Ilia, Zylka, Mark J., Hull-Ryde, Emily A., Frye, Stephen V., Janzen, William P., Rittiner, Joseph E., Jin, Jian
Numerous receptors for ATP, ADP, and adenosine exist; however, it is currently unknown whether a receptor for the related nucleotide adenosine 5′-monophosphate (AMP) exists. Using a novel cell-based assay to visualize adenosine receptor activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54b58781a1c03b1f052fd3fdc51c073d
Autor:
Korboukh, Ilia, Setola, Vincent, Randhawa, Amarjit S., Frye, Stephen V., Jin, Jian, Coleman, Jennifer, Janzen, William P., Fitzpatrick, Brendan J., Rittiner, Joseph E., Zylka, Mark J., Hull-Ryde, Emily A.
Adenosine A1 receptor (A1AR) agonists have antinociceptive effects in multiple preclinical models of acute and chronic pain. Although numerous A1AR agonists have been developed, clinical applications of these agents have been hampered by their cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aaa012ad9ed7d0648a1f7a9956a35d5
Autor:
Taylor-Blake, Bonnie, Street, Sarah E, Walsh, Paul L, Wightman, R. Mark, Sowa, Nathaniel A, Zylka, Mark J., Guillot, Thomas S
Background Prostatic acid phosphatase (PAP) and ecto-5'-nucleotidase (NT5E, CD73) produce extracellular adenosine from the nucleotide AMP in spinal nociceptive (pain-sensing) circuits; however, it is currently unknown if these are the main ectonucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f89b42d6bd90fcfddb86198a980eaeb
Prostatic acid phosphatase (PAP) is expressed in nociceptive dorsal root ganglion (DRG) neurons, functions as an ectonucleotidase, and generates adenosine extracellularly. Here, we found that PAP inhibits noxious thermal sensitivity and sensitization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ef4fa7f8ffbd8d7a1e26e46c089155b
https://europepmc.org/articles/PMC2920622/
https://europepmc.org/articles/PMC2920622/
The Mas-related genes (Mrgs) comprise a family of >50 G protein-coupled receptors (GPCRs), many of which are expressed in specific subsets of nociceptive sensory neurons in mice. In contrast, humans contain a related but nonorthologous family of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od________38::2a3fce21e784aa190e7ee97182f186b1
https://resolver.caltech.edu/CaltechAUTHORS:20141120-150144380
https://resolver.caltech.edu/CaltechAUTHORS:20141120-150144380
Autor:
Zylka, Mark J., Hurt, Julie K
Acupuncture has been used for millennia to treat pain, although its efficacy and duration of action is limited. Acupuncture also has brief (1–2 h) antinociceptive effects in mice and these effects are dependent on localized adenosine A1 receptor (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af2e51840f3e7e957e6fc369576b538c
Autor:
Zylka, Mark J., Taylor-Blake, Bonnie
Thiamine monophosphatase (TMPase, also known as Fluoride-resistant acid phosphatase or FRAP) is a classic histochemical marker of small- to medium-diameter dorsal root ganglia (DRG) neurons and has primarily been studied in the rat. Previously, we fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7570b6931d0231c23c6a5f94e9cd032