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of 19
pro vyhledávání: '"Thomas, Duncan C."'
Objective An understanding of the etiologic heterogeneity of colorectal cancer (CRC) is critical for improving precision prevention, including individualized screening recommendations and the discovery of novel drug targets and repurposable drug cand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::c3d58b33aa6d210f80edc7e65ee3dabe
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3029824
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3029824
Autor:
Reiner, Anne S, Sisti, Julia, John, Esther M, Lynch, Charles F, Brooks, Jennifer D, Mellemkjær, Lene, Boice, John D, Knight, Julia A, Concannon, Patrick, Capanu, Marinela, Tischkowitz, Marc, Robson, Mark, Liang, Xiaolin, Woods, Meghan, Conti, David V, Duggan, David, Shore, Roy, Stram, Daniel O, Thomas, Duncan C, Malone, Kathleen E, Bernstein, Leslie, WECARE Study Collaborative Group, Bernstein, Jonine L
Purpose The Women's Environmental Cancer and Radiation Epidemiology (WECARE) study demonstrated the importance of breast cancer family history on contralateral breast cancer (CBC) risk, even for noncarriers of deleterious BRCA1/2 mutations. With the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a8acb909e619c97df65c02ccdf6582
Autor:
Thomas, Duncan C.
Publikováno v:
Epidemiology (Cambridge, Mass.)
Supplemental Digital Content is available in the text.
Screening behavior depends on previous screening history and family members’ behaviors, which can act as both confounders and intermediate variables on a causal pathway from screening to d
Screening behavior depends on previous screening history and family members’ behaviors, which can act as both confounders and intermediate variables on a causal pathway from screening to d
Autor:
Brooks, Jennifer D., John, Esther M., Mellemkjær, Lene, Lynch, Charles F., Knight, Julia A., Malone, Kathleen E., Reiner, Anne S., Bernstein, Leslie, Liang, Xiaolin, Shore, Roy E., Stovall, Marilyn, Bernstein, Jonine L., Capanu, Marinela, Orlow, Irene, Robson, Mark, Woods, Meghan, Boice, John D., Brooks, Jennifer, Concannon, Patrick, Conti, Dave V., Duggan, David, Elena, Joanne W., Haile, Robert W., Olsen, Jørgen H., Seminara, Daniela, Stram, Daniel O., Tischkowitz, Marc, Thomas, Duncan C.
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 5, Iss 11, Pp 3282-3291 (2016)
Cancer Medicine, Vol 5, Iss 11, Pp 3282-3291 (2016)
Studies examining the relationship between body mass index (BMI) and risk of contralateral breast cancer (CBC) have reported mixed findings. We previously showed that obese postmenopausal women with estrogen receptor (ER)‐negative breast cancer hav
Background: Studies using metabolomic data have identified metabolites from several compound classes that are associated with disease-related lifestyle factors. Objective: In this study, we identified metabolic signatures reflecting lifestyle pattern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::07097c3ffeead6e17a09ad23c4bcc36e
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3180458
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3180458
Background: The “meeting-in-the-middle” (Nirmt) is a principle to identify exposure biornarkers that are also predictors of disease. The MITM statistical framework was applied in a nested case-control study of hepatocellular carcinoma (HCC) withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::4f11cc8b92dd712f1ea7f876e2907876
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3179634
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3179634
Autor:
Feng, Yen Chen Anne, Cho, Kelly, Lindstrom, Sara, Kraft, Peter, Cormack, Jean, Blalock, Kendra, Campbell, Peter T., Casey, Graham, Conti, David V., Edlund, Christopher K., Figueiredo, Jane, James Gauderman, W., Gong, Jian, Green, Roger C., Gruber, Stephen B., Harju, John F., Harrison, Tabitha A., Jacobs, Eric J, Jenkins, Mark A., Jiao, Shuo, Li, Li, Lin, Yi, Manion, Frank J., Moreno, Victor, Mukherjee, Bhramar, Peters, Ulrike, Raskin, Leon, Schumacher, Fredrick R., Seminara, Daniela, Severi, Gianluca, Stenzel, Stephanie L., Thomas, Duncan C., Hopper, John L., Southey, Melissa C., Makalic, Enes, Schmidt, Daniel F., Fletcher, Olivia, Peto, Julian, Gibson, Lorna, Dos-Santos-Silva, Isabel, Hunter, David J., Lindström, Sara, Ahsan, Habib, Whittemore, Alice S., Waisfisz, Quinten, Meijers-Heijboer, Hanne, Adank, Muriel A., van der Luijt, Rob B., Uitterlinden, Andre G, IGAP Consortium, Colorectal Transdisciplinary Study (CORECT), Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE), Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE), Transdisciplinary Research in Cancer of the Lung (TRICL)
Growing evidence from both epidemiology and basic science suggest an inverse association between Alzheimer’s disease (AD) and cancer. We examined the genetic relationship between AD and various cancer types using GWAS summary statistics from the IG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10691::d890e0ccc97e42b4dac3af0ae989eab2
https://dspace.library.uu.nl/handle/1874/357964
https://dspace.library.uu.nl/handle/1874/357964
Autor:
Feng, Yen Chen Anne, Cho, Kelly, Lindstrom, Sara, Kraft, Peter, Cormack, Jean, Blalock, Kendra, Campbell, Peter T., Casey, Graham, Conti, David V., Edlund, Christopher K., Figueiredo, Jane, James Gauderman, W., Gong, Jian, Green, Roger C., Gruber, Stephen B., Harju, John F., Harrison, Tabitha A., Jacobs, Eric J, Jenkins, Mark A., Jiao, Shuo, Li, Li, Lin, Yi, Manion, Frank J., Moreno, Victor, Mukherjee, Bhramar, Peters, Ulrike, Raskin, Leon, Schumacher, Fredrick R., Seminara, Daniela, Severi, Gianluca, Stenzel, Stephanie L., Thomas, Duncan C., Hopper, John L., Southey, Melissa C., Makalic, Enes, Schmidt, Daniel F., Fletcher, Olivia, Peto, Julian, Gibson, Lorna, Dos-Santos-Silva, Isabel, Hunter, David J., Lindström, Sara, Ahsan, Habib, Whittemore, Alice S., Waisfisz, Quinten, Meijers-Heijboer, Hanne, Adank, Muriel A., van der Luijt, Rob B., Uitterlinden, Andre G, IGAP Consortium, Colorectal Transdisciplinary Study (CORECT), Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE)
Publikováno v:
Human Genetics, 136(10), 1341-1351. Springer Verlag
Feng, Y C A, Cho, K, Lindstrom, S, Kraft, P, Cormack, J, IGAP Consortium, Colorectal Transdisciplinary Study (CORECT), Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE), Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) & Transdisciplinary Research in Cancer of the Lung (TRICL) 2017, ' Investigating the genetic relationship between Alzheimer’s disease and cancer using GWAS summary statistics ', Human Genetics, vol. 136, no. 10, pp. 1341-1351 . https://doi.org/10.1007/s00439-017-1831-6
Human Genetics, 136(10), 1341. Springer Verlag
Feng, Y C A, Cho, K, Lindstrom, S, Kraft, P, Cormack, J, IGAP Consortium, Colorectal Transdisciplinary Study (CORECT), Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE), Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) & Transdisciplinary Research in Cancer of the Lung (TRICL) 2017, ' Investigating the genetic relationship between Alzheimer’s disease and cancer using GWAS summary statistics ', Human Genetics, vol. 136, no. 10, pp. 1341-1351 . https://doi.org/10.1007/s00439-017-1831-6
Human Genetics, 136(10), 1341. Springer Verlag
Growing evidence from both epidemiology and basic science suggest an inverse association between Alzheimer’s disease (AD) and cancer. We examined the genetic relationship between AD and various cancer types using GWAS summary statistics from the IG
Autor:
Khankari, Nikhil K., Shu, Xiao Ou, Wen, Wanqing, Kraft, Peter, Lindström, Sara, Peters, Ulrike, Schildkraut, Joellen, Schumacher, Fredrick, Bofetta, Paolo, Risch, Angela, Bickeböller, Heike, Amos, Christopher I., Easton, Douglas, Eeles, Rosalind A., Gruber, Stephen B., Haiman, Christopher A., Hunter, David J., Chanock, Stephen J., Pierce, Brandon L., Zheng, Wei, Blalock, Kendra, Campbell, Peter T., Casey, Graham, Conti, David V., Edlund, Christopher K., Figueiredo, Jane, James Gauderman, W., Gong, Jian, Green, Roger C., Harju, John F., Harrison, Tabitha A., Jacobs, Eric J., Jenkins, Mark A., Jiao, Shuo, Li, Li, Lin, Yi, Manion, Frank J., Moreno, Victor, Mukherjee, Bhramar, Raskin, Leon, Schumacher, Fredrick R., Seminara, Daniela, Severi, Gianluca, Stenzel, Stephanie L., Thomas, Duncan C., Hopper, John L., Southey, Melissa C., Makalic, Enes, Schmidt, Daniel F., Fletcher, Olivia, Peto, Julian, Gibson, Lorna, dos Santos Silva, Isabel, Ahsan, Habib, Whittemore, Alice, Waisfisz, Quinten, Meijers-Heijboer, Hanne, Adank, Muriel, van der Luijt, Rob B., Uitterlinden, Andre G., Hofman, Albert, Meindl, Alfons, Schmutzler, Rita K., Müller-Myhsok, Bertram, Lichtner, Peter, Nevanlinna, Heli, Muranen, Taru A., Aittomäki, Kristiina, Blomqvist, Carl, Chang-Claude, Jenny, Hein, Rebecca, Dahmen, Norbert, Beckman, Lars, Crisponi, Laura, Hall, Per, Czene, Kamila, Irwanto, Astrid, Liu, Jianjun, Easton, Douglas F., Turnbull, Clare, Rahman, Nazneen, Eeles, Rosalind, Kote-Jarai, Zsofia, Muir, Kenneth, Giles, Graham, Neal, David, Donovan, Jenny L., Hamdy, Freddie C., Wiklund, Fredrik, Gronberg, Henrik, Haiman, Christopher, Schumacher, Fred, Travis, Ruth, Riboli, Elio, Hunter, David, Gapstur, Susan, Berndt, Sonja, Chanock, Stephen, Han, Younghun, Su, Li, Wei, Yongyue, Hung, Rayjean J., Brhane, Yonathan, McLaughlin, John, Brennan, Paul, McKay, James D., Rosenberger, Albert, Houlston, Richard S., Caporaso, Neil, Teresa Landi, Maria, Heinrich, Joachim, Wu, Xifeng, Ye, Yuanqing, Christiani, David C.
Publikováno v:
Khankari, N K, Shu, X O, Wen, W, Kraft, P, Lindström, S, Peters, U, Schildkraut, J, Schumacher, F, Bofetta, P, Risch, A, Bickeböller, H, Amos, C I, Easton, D, Eeles, R A, Gruber, S B, Haiman, C A, Hunter, D J, Chanock, S J, Pierce, B L, Zheng, W, Blalock, K, Campbell, P T, Casey, G, Conti, D V, Edlund, C K, Figueiredo, J, James Gauderman, W, Gong, J, Green, R C, Harju, J F, Harrison, T A, Jacobs, E J, Jenkins, M A, Jiao, S, Li, L, Lin, Y, Manion, F J, Moreno, V, Mukherjee, B, Raskin, L, Schumacher, F R, Seminara, D, Severi, G, Stenzel, S L, Thomas, D C, Hopper, J L, Southey, M C, Makalic, E, Schmidt, D F, Fletcher, O, Peto, J, Gibson, L, dos Santos Silva, I, Ahsan, H, Whittemore, A, Waisfisz, Q, Meijers-Heijboer, H, Adank, M, van der Luijt, R B, Uitterlinden, A G, Hofman, A, Meindl, A, Schmutzler, R K, Müller-Myhsok, B, Lichtner, P, Nevanlinna, H, Muranen, T A, Aittomäki, K, Blomqvist, C, Chang-Claude, J, Hein, R, Dahmen, N, Beckman, L, Crisponi, L, Hall, P, Czene, K, Irwanto, A, Liu, J, Easton, D F, Turnbull, C, Rahman, N, Eeles, R, Kote-Jarai, Z, Muir, K, Giles, G, Neal, D, Donovan, J L, Hamdy, F C, Wiklund, F, Gronberg, H, Haiman, C, Schumacher, F, Travis, R, Riboli, E, Hunter, D, Gapstur, S, Berndt, S, Chanock, S, Han, Y, Su, L, Wei, Y, Hung, R J, Brhane, Y, McLaughlin, J, Brennan, P, McKay, J D, Rosenberger, A, Houlston, R S, Caporaso, N, Teresa Landi, M, Heinrich, J, Wu, X, Ye, Y & Christiani, D C 2016, ' Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer : Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses ', PLoS Medicine, vol. 13, no. 9, e1002118 . https://doi.org/10.1371/journal.pmed.1002118
PLoS Medicine, 13(9). Public Library of Science
PLoS Medicine
PLoS Medicine, 13(9):e1002118. Public Library of Science
PLoS medicine
PLoS Medicine, Vol 13, Iss 9, p e1002118 (2016)
PLoS Medicine, 13(9). Public Library of Science
PLoS Medicine
PLoS Medicine, 13(9):e1002118. Public Library of Science
PLoS medicine
PLoS Medicine, Vol 13, Iss 9, p e1002118 (2016)
Background Observational studies examining associations between adult height and risk of colorectal, prostate, and lung cancers have generated mixed results. We conducted meta-analyses using data from prospective cohort studies and further carried ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6fe202ba21d2065244a4dd05f37f41
https://research.vumc.nl/en/publications/220697d3-2b7c-4b12-be2f-6f64f4739729
https://research.vumc.nl/en/publications/220697d3-2b7c-4b12-be2f-6f64f4739729
Autor:
Schumacher, Fredrick R, Schmit, Stephanie L, Jiao, Shuo, Edlund, Christopher K, Wang, Hansong, Zhang, Ben, Hsu, Li, Huang, Shu-Chen, Fischer, Christopher P, Harju, John F, Idos, Gregory E, Lejbkowicz, Flavio, Manion, Frank J, McDonnell, Kevin, McNeil, Caroline E, Melas, Marilena, Rennert, Hedy S, Shi, Wei, Thomas, Duncan C, Van Den Berg, David J, Hutter, Carolyn M, Aragaki, Aaron K, Butterbach, Katja, Caan, Bette J, Carlson, Christopher S, Chanock, Stephen J, Curtis, Keith R, Fuchs, Charles S, Gala, Manish, Giovannucci, Edward L, Gogarten, Stephanie M, Hayes, Richard B, Henderson, Brian, Hunter, David J, Jackson, Rebecca D, Kolonel, Laurence N, Kooperberg, Charles, Küry, Sébastien, LaCroix, Andrea, Laurie, Cathy C, Laurie, Cecelia A, Lemire, Mathieu, Levine, David, Ma, Jing, Makar, Karen W, Qu, Conghui, Taverna, Darin, Ulrich, Cornelia M, Wu, Kana, Kono, Suminori, West, Dee W, Berndt, Sonja I, Bezieau, Stéphane, Brenner, Hermann, Campbell, Peter T, Chan, Andrew T, Chang-Claude, Jenny, Coetzee, Gerhard A, Conti, David V, Duggan, David, Figueiredo, Jane C, Fortini, Barbara K, Gallinger, Steven J, Gauderman, W James, Giles, Graham, Green, Roger, Haile, Robert, Harrison, Tabitha A, Hoffmeister, Michael, Hopper, John L, Hudson, Thomas J, Jacobs, Eric, Iwasaki, Motoki, Jee, Sun Ha, Jenkins, Mark, Jia, Wei-Hua, Joshi, Amit, Li, Li, Lindor, Noralene M, Matsuo, Keitaro, Moreno, Victor, Mukherjee, Bhramar, Newcomb, Polly A, Potter, John D, Raskin, Leon, Rennert, Gad, Rosse, Stephanie, Severi, Gianluca, Schoen, Robert E, Seminara, Daniela, Shu, Xiao-Ou, Slattery, Martha L, Tsugane, Shoichiro, White, Emily, Xiang, Yong-Bing, Zanke, Brent W, Zheng, Wei, Le Marchand, Loic, Casey, Graham, Gruber, Stephen B, Peters, Ulrike
Publikováno v:
Schumacher, Fredrick R; Schmit, Stephanie L; Jiao, Shuo; Edlund, Christopher K; Wang, Hansong; Zhang, Ben; et al.(2015). Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nature Communications, 6(1). doi: 10.1038/ncomms8138. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/49b704wg
Genetic susceptibility to colorectal cancer is caused by rare pathogenic mutations and common genetic variants that contribute to familial risk. Here we report the results of a two-stage association study with 18,299 cases of colorectal cancer and 19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::bdc42dfc30d3f6426b5a16897d7a6ad3
http://www.escholarship.org/uc/item/49b704wg
http://www.escholarship.org/uc/item/49b704wg