Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Stefania Lenna"'
Autor:
Stefania Lenna, Ava Brozovich, Takashi Hirase, Francesca Paradiso, Bradley K. Weiner, Francesca Taraballi
Publikováno v:
Stem Cells and Development. 31:672-683
Due to their immunosuppressive potential and ability to differentiate into multiple musculoskeletal cell lineages, mesenchymal stromal cells (MSCs) became popular in clinical trials for the treatment of musculoskeletal disorders. The aim of this stud
Autor:
Tetsuo Toyama, Tatiana V. Kudryashova, Asako Ichihara, Stefania Lenna, Agnieszka Looney, Yuanjun Shen, Lifeng Jiang, Leyla Teos, Theodore Avolio, Derek Lin, Ulas Kaplan, Grace Marden, Vrinda Dambal, Dmitry Goncharov, Horace Delisser, Robert Lafyatis, Francesca Seta, Elena A. Goncharova, Maria Trojanowska
Publikováno v:
Scientific reports, vol 13, iss 1
Pulmonary arterial hypertension (PAH) is a life-threatening condition characterized by a progressive increase in pulmonary vascular resistance leading to right ventricular failure and often death. Here we report that deficiency of transcription facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7629a7fe602bc2dd744cfe82e75d86a6
https://escholarship.org/uc/item/92n3k88f
https://escholarship.org/uc/item/92n3k88f
Autor:
Ava A Brozovich, Stefania Lenna, Francesca Paradiso, Stefano Serpelloni, Patrick McCulloch, Bradley Weiner, Jason T Yustein, Francesca Taraballi
Publikováno v:
Journal of tissue engineering. 13
Osteosarcoma (OS) is the most common bone tumor in pediatrics. After resection, allografts or metal endoprostheses reconstruct bone voids, and systemic chemotherapy is used to prevent recurrence. This urges the development of novel treatment options
Autor:
Federica Giordano, Stefania Lenna, Gherardo Baudo, Riccardo Rampado, Matteo Massaro, Enrica De Rosa, April Ewing, Lyazat Kurenbekova, Marco Agostini, Jason T. Yustein, Francesca Taraballi
Small-molecule tyrosine kinase inhibitors (TKIs) represent a potentially powerful approach to the treatment of osteosarcoma (OS). However, dose-limiting toxicity, therapeutic efficacy, and targeting specificity are significant barriers to the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe62408e3ae690de73edcd4280c6d39
https://hdl.handle.net/11577/3465160
https://hdl.handle.net/11577/3465160
Autor:
Francesca Paradiso, Marcos Quintela, Stefania Lenna, Stefano Serpelloni, David James, Sergio Caserta, Steve Conlan, Lewis Francis, Francesca Taraballi
Publikováno v:
Macromolecular bioscience. 22(4)
Fibrosis and solid tumor progression are closely related, with both involving pathways associated with chronic wound dysregulation. Fibroblasts contribute to extracellular matrix (ECM) remodeling in these processes, a crucial step in scarring, organ
Autor:
Ha Ram Kim, Tomoyuki Naoi, April Ewing, Matteo Massaro, Francesca Taraballi, Gherardo Baudo, Jason T. Yustein, Ennio Tasciotti, Stefania Lenna, Assaf Zinger, Federica Giordano
Publikováno v:
ACS Applied Bio Materials. 3:6737-6745
Ponatinib (Pon) is a multi-tyrosine kinase inhibitor that demonstrated high efficiency for treating cancer. However, severe side effects caused by Pon off-targeting effects prevent its extensive use. Using our understanding into the mechanisms by whi
Autor:
Federica Giordano, Stefania Lenna, Riccardo Rampado, Gherardo Baudo, Matteo Massaro, Ashley Rivera, Enrica De Rosa, Jason T. Yustein, Francesca Taraballi
Publikováno v:
Cancer Research. 82:307-307
The introduction of targeted anticancer drugs has revolutionized treatment. Multi-tyrosine kinase inhibitors (TKIs) are potential therapeutics targeting specific signaling pathways that contribute to cancer progression, including sarcomas. Osteosarco
Autor:
Jason T. Yustein, Riccardo Rampado, Mauro Tognon, Stefania Lenna, Takashi Hirase, Fernanda Martini, Marco Agostini, Federica Giordano, Francesca Taraballi, Ava Brozovich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10be8c681a5ab04b628d7055226bc4e
http://hdl.handle.net/11577/3459739
http://hdl.handle.net/11577/3459739
Autor:
Lewis Francis, Marcos Quintela, R.S. Conlan, Francesca Taraballi, Francesca Paradiso, David James, Sergio Caserta, Stefano Serpelloni, Stefania Lenna
Publikováno v:
SSRN Electronic Journal.
The complexity of studying a neoplastic disease relies on understanding specialized cell types within the tumor tissue, which can be recruited and ‘corrupted’ to create a dynamic pro-tumorigenic network called the ‘tumor microenvironment’ (TM
Autor:
Gareth D. Healey, Fereshteh Izardi, Bruna Corradetti, Lucille Meeks, Deyarina Gonzalez, Yajaira S Jimenez, Stefania Lenna, Simone Pisano, Oscar S Velazquez, Robert Steven Conlan
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 10, Pp n/a-n/a (2021)
Clinical and Translational Medicine
Clinical and Translational Medicine
Background Ovarian cancer (OC) is typically diagnosed late, associated with high rates of metastasis and the onset of ascites during late stage disease. Understanding the tumor microenvironment and how it impacts the efficacy of current treatments, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc320113859ca17d7eddf98da0238ebb
https://cronfa.swan.ac.uk/Record/cronfa58302/Download/58302__21358__3cb24df0ca544182a96f0b3f6c70ad22.pdf
https://cronfa.swan.ac.uk/Record/cronfa58302/Download/58302__21358__3cb24df0ca544182a96f0b3f6c70ad22.pdf