Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sinu, P."'
Autor:
Akash Bisoyi, Alisha Rani Tripathy, Girish Suresh Yedase, Shifana Sinu P, Udita Choudhury, Veera Reddy Yatham
Publikováno v:
The Journal of Organic Chemistry. 88:2631-2641
Autor:
Clinton J. Bradfield, Jonathan J. Liang, Orna Ernst, Sinu P. John, Jing Sun, Sundar Ganesan, Adriana A. de Jesus, Clare E. Bryant, Raphaela Goldbach-Mansky, Iain D. C. Fraser
Publikováno v:
Cell Death & Differentiation. 30:589-604
Autor:
Sinu P. John, Anju Singh, Jing Sun, Makheni Jean Pierre, Lulwah Alsalih, Crystal Lipsey, Ziann Traore, Shenavia Balcom-Luker, Clinton J. Bradfield, Jian Song, Tovah E. Markowitz, Margery Smelkinson, Marc Ferrer, Iain D.C. Fraser
Publikováno v:
Cell reports. 41(1)
Biologically active small molecules can impart modulatory effects, in some cases providing extended long-term memory. In a screen of biologically active small molecules for regulators of tumor necrosis factor (TNF) induction, we identify several comp
Autor:
Michael G Dorrington, Clinton J Bradfield, Justin B Lack, Bin Lin, Sinu P John, Jonathan J Liang, Tregei Starr, Orna Ernst, Julia L Gross, Jing Sun, Alexandra H Miller, Olivia Steele-Mortimer, Iain D C Fraser
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8 (2021)
PLoS Pathogens, Vol 17, Iss 8, p e1009821 (2021)
PLoS Pathogens, Vol 17, Iss 8, p e1009821 (2021)
[This corrects the article DOI: 10.1371/journal.ppat.1009395.].
Autor:
Jing Sun, Jian Song, Binh Cao, Margery G. Smelkinson, Clinton J. Bradfield, Rebecca J. Carlson, Sinu P. John, Iain D. C. Fraser
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 95-106.e6 (2018)
Cell reports
Cell reports
SUMMARY Activation of the TLR4 signaling pathway by lipopoly-saccharide (LPS) leads to induction of both inflammatory and interferon-stimulated genes, but the mechanisms through which these coordinately activated transcriptional programs are balanced
Autor:
Sinu P. John, William M. McDougall, Jocelyn M. Portmann, Abraham L. Brass, Sharone Green, Jill M. Perreira, George Savidis, Zhiru Guo, Paul Meraner, Douglas Robbins, Gaia Trincucci, Timothy F. Kowalik, Aaron M. Aker, Nicholas Renzette
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 232-246 (2016)
SummaryThe flaviviruses dengue virus (DENV) and Zika virus (ZIKV) are severe health threats with rapidly expanding ranges. To identify the host cell dependencies of DENV and ZIKV, we completed orthologous functional genomic screens using RNAi and CRI
Autor:
Prashant Desai, Sydney Simpson, Netty Santoso, Jian Zhu, Meir Shamay, Maxime Jean, Michael Dieringer, James McGuinness, Guillaume Fiches, Sinu P. John
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 9 (2018)
Frontiers in Microbiology, Vol 9 (2018)
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic virus responsible for the development of Kaposi's sarcoma, primary effusion lymphoma (PEL), and Multicentric Castleman's disease in immunocompromised individuals. Despite the burden of th
Autor:
Qikai Xu, Louise Maranda, Teresa Davoli, Sinu P. John, Thomas Pertel, Christopher R. Chin, Hongjing Qu, Richard Baker, Jian Zhu, Jennifer A. Smith, Abraham L. Brass, Geng Gao, Jill M. Perriera, Stephen J. Elledge, Frederic D. Sigiollot, Aylwin Ng, Gaurav D. Gaiha, Jennifer S. Sims
Publikováno v:
Cell Reports, Vol 9, Iss 2, Pp 752-766 (2014)
Cell reports
Cell reports
SUMMARY RNAi screens have implicated hundreds of host proteins as HIV-1 dependency factors (HDFs). While informative, these early studies overlap poorly due to false positives and false negatives. To ameliorate these issues, we combined information f
Autor:
Thomas Pertel, Stephen J. Elledge, Andrew E. H. Elia, Mehul Vora, Sarah E. Smith, Eric M. Feeley, Aaron M. Aker, George Savidis, Sinu P. John, Christopher R. Chin, Jill M. Perreira, Paul Kellam, Abraham L. Brass, Aaron R. Everitt
Publikováno v:
Journal of Virology
The interferon-induced transmembrane protein 3 (IFITM3) gene is an interferon-stimulated gene that inhibits the replication of multiple pathogenic viruses in vitro and in vivo . IFITM3 is a member of a large protein superfamily, whose members share a
Autor:
Ning Li, Iain D. C. Fraser, Ze Wang, Sinu P. John, Zachary L. Benet, Bin Lin, Myong-Hee Sung, Souhaila Al-Khodor, Jing Sun
Publikováno v:
Scientific Reports
Macrophages play a critical role in the innate immune response to pathogen infection, but few tools exist for systematic dissection of these responses using modern genome-wide perturbation methods. To develop an assay platform for high-throughput ana