Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Merle Stein"'
Autor:
Benjamin Barth, Christoph Linhart, Felix N. Schmidt, Merle Stein, Kai Oliver Boeker, Ines Foessl, Marietta Herrmann, F Genest, Andrea Schwab
Publikováno v:
Osteologie. 30:157-162
ZUSAMMENFASSUNGFür junge Forscher*innen am Beginn des Karriereweges sind Instrumente der Nachwuchsförderung und -vernetzung von großer Bedeutung. Unterstützung ist hier in vielen Bereichen notwendig, vom Erwerb sogenannter Soft Skills, der Auswei
Autor:
Moran Shalev, Sergey Kapishnikov, Esther Arman, Merle Stein, Isabelle Royal, Vlad Brumfeld, Ari Elson, Jan Tuckermann, Yael Cohen-Sharir
Publikováno v:
The FEBS Journal. 288:4702-4723
Bone-resorbing osteoclasts (OCLs) are multinucleated phagocytes, whose central roles in regulating bone formation and homeostasis are critical for normal health and development. OCLs are produced from precursor monocytes in a multistage process that
Autor:
Fadi Thalji, Jan Tuckermann, Merle Stein, Sabina Winograd-Katz, Benjamin Geiger, Esther Arman, Moien Kanaan, Moran Shalev, Ari Elson, Lee Roth, Nina Reuven, Ofra Golani, Maayan Barnea-Zohar
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Homozygosity for the R51Q mutation in sorting nexin 10 (SNX10) inactivates osteoclasts (OCLs) and induces autosomal recessive osteopetrosis in humans and in mice. We show here that the fusion of wild-type murine monocytes to form OCLs is highly regul
Autor:
Mubashir Ahmad, Sooyeon Lee, Sabine Vettorazzi, Mehmet Sacma, Merle Stein, Ann-Kristin Dorn, Ute Burret, Anita Ignatius, Hartmut Geiger, Jan Tuckermann
Publikováno v:
Bone Reports. 16:101292
Autor:
Benjamin Geiger, Polina Stepensky, F Thalji, Maayan Barnea, Merle Stein, Moien Kanaan, Ari Elson, Jan Tuckermann, Hila Elinav, Sabina Winograd-Katz, Esther Arman, Moran Shalev, Ori Brenner
Publikováno v:
1. MuSkITYR Symposium.
Autor:
Aline Bozec, Georg Schett, Kenia Ubieta, Georg F. Weber, Dirk Mielenz, Arif B. Ekici, Mireia Garcia, Steffen Uebe, Bettina Grötsch, Merle Stein
Publikováno v:
The Journal of Experimental Medicine
The role of AP-1 transcription factors in early B cell development and function is still incompletely characterized. Ubieta at al. describe the function of the Fra-2/AP-1 transcription factor as a regulator of Foxo1 and Irf4 expression in B cells. Fr
Autor:
Lee, Roth, Jean, Wakim, Elad, Wasserman, Moran, Shalev, Esther, Arman, Merle, Stein, Vlad, Brumfeld, Cari A, Sagum, Mark T, Bedford, Jan, Tuckermann, Ari, Elson
Publikováno v:
Science signaling. 12(563)
Bone resorption by osteoclasts is essential for bone homeostasis. The kinase Src promotes osteoclast activity and is activated in osteoclasts by the receptor-type tyrosine phosphatase PTPROt. In other contexts, however, PTPROt can inhibit Src activit
Autor:
Mark T. Bedford, Ari Elson, Jan Tuckermann, Esther Arman, Moran Shalev, Jean Wakim, Merle Stein, Vlad Brumfeld, Cari A. Sagum, Elad Wasserman, Lee Roth
Publikováno v:
Science Signaling. 12
Bone resorption by osteoclasts is essential for bone homeostasis. The kinase Src promotes osteoclast activity and is activated in osteoclasts by the receptor-type tyrosine phosphatase PTPROt. In other contexts, however, PTPROt can inhibit Src activit
Autor:
Maayan Barnea-Zohar, Sabina Winograd-Katz, Polina Stepensky, Jennifer Gerstung, Fadi Thalji, Merle Stein, Hila Elinav, Jan Tuckermann, Moien Kanaan, Benjamin Geiger, Esther Arman, Ari Elson, Ori Brenner, Moran Shalev
Publikováno v:
Bone. 136:115360
The R51Q mutation in sorting nexin 10 (SNX10) was shown to cause a lethal genetic disease in humans, namely autosomal recessive osteopetrosis (ARO). We describe here the first R51Q SNX10 knock-in mouse model and show that mice homozygous for this mut
Autor:
Moran Shalev, Moien Kanaan, Sabina Winograd-Katz, Polina Stepensky, Ori Brenner, Fadi Thalji, Esther Arman, Merle Stein, Hila Elinav, Jan Tuckermann, Benjamin Geiger, Ari Elson, Maayan Barnea
SummaryThe molecular mechanisms that regulate fusion of monocytes into functional osteoclasts are virtually unknown. We describe a knock-in mouse model for the R51Q mutation in sorting nexin 10 (SNX10) that exhibits osteopetrosis and related symptoms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59af484292836e6ee7bdf864c69482c4