Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Manabu, Igarashi"'
Publikováno v:
The Journal of Infectious Diseases.
Our previous study demonstrated that the fruit bat (Yaeyama flying fox)-derived cell line FBKT1 showed preferential susceptibility to Ebola virus (EBOV), whereas the human cell line HEK293T was similarly susceptible to EBOV and Marburg virus (MARV).
Autor:
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H. Christensen, Yonas M. Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian I. Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate M. Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa E. Müller, Manabu Igarashi, Hiroki Kato
Publikováno v:
Tsukamoto, Y, Hiono, T, Yamada, S, Matsuno, K, Faist, A, Claff, T, Hou, J, Namasivayam, V, vom Hemdt, A, Sugimoto, S, Ng, J Y, Christensen, M H, Tesfamariam, Y M, Wolter, S, Juranek, S, Zillinger, T, Bauer, S, Hirokawa, T, Schmidt, F I, Kochs, G, Shimojima, M, Huang, Y S, Pichlmair, A, Kümmerer, B M, Sakoda, Y, Schlee, M, Brunotte, L, Müller, C E, Igarashi, M & Kato, H 2023, ' Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication ', Science, vol. 379, no. 6632, pp. 586-591 . https://doi.org/10.1126/science.add0875
Orthomyxo- and bunyaviruses steal the 5′ cap portion of host RNAs to prime their own transcription in a process called “cap snatching.” We report that RNA modification of the cap portion by host 2′-O-ribose methyltransferase 1 (MTr1) is essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ca613036512c6c980ca13774bda357
https://pure.au.dk/portal/da/publications/inhibition-of-cellular-rna-methyltransferase-abrogates-influenza-virus-capping-and-replication(e57afff0-1209-4d3e-92f4-f592420aad55).html
https://pure.au.dk/portal/da/publications/inhibition-of-cellular-rna-methyltransferase-abrogates-influenza-virus-capping-and-replication(e57afff0-1209-4d3e-92f4-f592420aad55).html
Autor:
Haruhiko Kamiki, Shin Murakami, Takashi Nishikaze, Takahiro Hiono, Manabu Igarashi, Yuki Furuse, Hiromichi Matsugo, Hiroho Ishida, Misa Katayama, Wataru Sekine, Yasushi Muraki, Masateru Takahashi, Akiko Takenaka-Uema, Taisuke Horimoto
Publikováno v:
J Virol
Avian or human influenza A viruses bind preferentially to avian- or human-type sialic acid receptors, respectively, indicating that receptor tropism is an important factor for determining the viral host range. However, there are currently no reliable
Autor:
Boniface Pongombo Lombe, Takeshi Saito, Hiroko Miyamoto, Akina Mori-Kajihara, Masahiro Kajihara, Masayuki Saijo, Justin Masumu, Takanari Hattori, Manabu Igarashi, Ayato Takada
Publikováno v:
Viruses; Volume 14; Issue 3; Pages: 544
Crimean-Congo hemorrhagic fever virus (CCHFV), a nairovirus, is a tick-borne zoonotic virus that causes hemorrhagic fever in humans. The CCHFV nucleoprotein (NP) is the antigen most used for serological screening of CCHFV infection in animals and hum
Autor:
Valter Bergant, Shintaro Yamada, Vincent Grass, Yuta Tsukamoto, Teresa Lavacca, Karsten Krey, Maria‐Teresa Mühlhofer, Sabine Wittmann, Armin Ensser, Alexandra Herrmann, Anja vom Hemdt, Yuriko Tomita, Shutoku Matsuyama, Takatsugu Hirokawa, Yiqi Huang, Antonio Piras, Constanze A Jakwerth, Madlen Oelsner, Susanne Thieme, Alexander Graf, Stefan Krebs, Helmut Blum, Beate M Kümmerer, Alexey Stukalov, Carsten B Schmidt‐Weber, Manabu Igarashi, Thomas Gramberg, Andreas Pichlmair, Hiroki Kato
The SARS‐CoV‐2 infection cycle is a multistage process that relies on functional interactions between the host and the pathogen. Here, we repurposed antiviral drugs against both viral and host enzymes to pharmaceutically block methylation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ad981d0b93c9a8add6f05e47e634f2
https://mediatum.ub.tum.de/doc/1689204/document.pdf
https://mediatum.ub.tum.de/doc/1689204/document.pdf
Publikováno v:
PeerJ Physical Chemistry, Vol 3, p e19 (2021)
The substitution of Ile to Val at residue 117 (I117V) of neuraminidase (NA) reduces the susceptibility of the A/H5N1 influenza virus to oseltamivir (OTV). However, the molecular mechanism by which the I117V mutation affects the intermolecular interac
Autor:
Shiho Torii, Tsogtbaatar Urangoo, Keita Matsuno, Yoshihiro Takadate, Khanui Buyantogtokh, Takeshi Saito, Kosuke Okuya, Ankhanbaatar Ulaankhuu, Khishgee Bodisaikhan, Takanari Hattori, Masatoshi Okamatsu, Manabu Igarashi, Yoshihiro Sakoda, Jargalsaikhan Tserenjav, Damdinjav Batchuluun, Yurie Kida, Hiroshi Kida, Mao Isono, Junki Maruyama, Tsolmon Amartuvshin, Masahiro Sato, Enkhbold Bazarragchaa, Takahiro Hiono, Ayato Takada, Tatsunari Kondoh, Nodoka Kasajima
Publikováno v:
Virus Genes
The circulation of highly pathogenic avian influenza viruses (HPAIVs) of various subtypes (e.g., H5N1, H5N6, H5N8, and H7N9) in poultry remains a global concern for animal and public health. Migratory waterfowls play important roles in the transmissi
Autor:
Kengo Kawachi, Masayuki Shimojima, Miyuki Kimura, Shigeru Morikawa, Manabu Igarashi, Hideki Tani, Masayuki Saijo, Satoshi Taniguchi, Shuetsu Fukushi
Publikováno v:
Virology. 535:102-110
Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease with a high fatality rate, caused by SFTS virus (SFTSV). Because little is known about the nature of SFTSV, basic studies are required for the developments of vaccines and ef
Autor:
Yoko Fujita-Fujiharu, Yukihiko Sugita, Yuki Takamatsu, Kazuya Houri, Manabu Igarashi, Yukiko Muramoto, Masahiro Nakano, Yugo Tsunoda, Ichiro Taniguchi, Stephan Becker, Takeshi Noda
Publikováno v:
Nature communications. 13(1)
The nucleoprotein (NP) of Marburg virus (MARV), a close relative of Ebola virus (EBOV), encapsidates the single-stranded, negative-sense viral genomic RNA (vRNA) to form the helical NP–RNA complex. The NP–RNA complex constitutes the core structur
Autor:
Taksoo Kim, Manabu Igarashi, Shizuka Hirose, Norikazu Isoda, Yoshihiro Sakoda, Loc Tan Huynh, Takahiro Hiono
Publikováno v:
Viruses, Vol 13, Iss 1672, p 1672 (2021)
Viruses
Volume 13
Issue 8
Viruses
Volume 13
Issue 8
The GPE− strain is a live attenuated vaccine for classical swine fever (CSF) developed in Japan. In the context of increasing attention for the differentiating infected from vaccinated animals (DIVA) concept, the achievement of CSF eradication with