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of 10
pro vyhledávání: '"Levine, Adrian"'
Autor:
Levine, Adrian, Lee, Carol, Fava, Craig, Tsang, Frankie, MacNeil, Kelly, Yip, Stephen, Hirsch-Reinshagen, Veronica
Publikováno v:
Free Neuropathol
Free Neuropathology, Vol 2 (2021)
Free Neuropathology, Vol 2 (2021)
Infection with the SARS-CoV-2 virus affects a wide range of systems. Significant involvement of the central nervous system has been described, including ischemic and hemorrhagic strokes. Thus far, neuropathologic reports of patients who passed away f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879b2aa78e9a55891b4b9a7da13fb348
https://europepmc.org/articles/PMC10209866/
https://europepmc.org/articles/PMC10209866/
Autor:
Wong, Derek, Sogerer, Lisa, Lee, Samantha S., Wong, Victor, Lum, Amy, Levine, Adrian B., Marra, Marco A., Yip, Stephen
Additional file 7: Figure S6 Validation of CIC-ATXN1L-TRIM25 Interaction. A) Representative Western blot of GBM cell lines treated with MEK/ERK inhibitors trametinib/LY3214996 for 16 hours. DMSO was used as a negative control. B) Representative Weste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a9b78d1399f7df16ffb5d59a3dec66
Autor:
Wong, Derek, Sogerer, Lisa, Lee, Samantha S., Wong, Victor, Lum, Amy, Levine, Adrian B., Marra, Marco A., Yip, Stephen
Additional file 1: Figure S1 Loss of ATXN1L results in CIC instability. A) Representative Western blot of FLAG immunoprecipitation of FLAG-tagged wildtype ATXN1L and mutant ATXN1L-V485A in HEK cells. B) Representative Western blot of cellular fractio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3516ab9f8d584543ff56369748c40033
Autor:
Wong, Derek, Sogerer, Lisa, Lee, Samantha S., Wong, Victor, Lum, Amy, Levine, Adrian B., Marra, Marco A., Yip, Stephen
Additional file 11: Figure S7 Pathways dysregulated by TRIM25-CIC. Heatmap showing the top 20 enriched gene sets for directionally discordant differentially expressed genes shared between TRIM25 siRNA in BT549 and MDA-MB-231 breast cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa3ea708282cdeca38ec6f497166c02e
Autor:
Wong, Derek, Sogerer, Lisa, Lee, Samantha S., Wong, Victor, Lum, Amy, Levine, Adrian B., Marra, Marco A., Yip, Stephen
Additional file 6: Figure S5 Characterization of GBM and BTIC lines. A) Relative mRNA expression of CIC target genes ETV1/4/5, DUSP6, and SPRY4 in GBM cell lines. Expression was normalized to TBP and NHA was used as a relative control. B) Relative mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6990f3f3dc577f14de18d563f8d79299
Autor:
Wong, Derek, Sogerer, Lisa, Lee, Samantha S., Wong, Victor, Lum, Amy, Levine, Adrian B., Marra, Marco A., Yip, Stephen
Additional file 5: Figure S4 CIC interactors. A) Representative Western blot of CICKO cells with stable FLAG tagged CIC-S reintroduced treated with ATXN1L siRNA over 72 hours. Scrambled siRNA was used as a negative control. B) Immunofluorescence imag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d549aad9acf520583d36eeb9ab7458e
Autor:
Wong, Derek, Sogerer, Lisa, Lee, Samantha S., Wong, Victor, Lum, Amy, Levine, Adrian B., Marra, Marco A., Yip, Stephen
Additional file 2: Figure S2 ERK dysregulates CIC function. A) Representative Western blot of ATXN1LWT (NHA) and ATXN1LKO (B82) cell lines treated with FGF/EGF over 0-24 hours following serum starvation. FBS control was cultured in FBS for the durati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9439857e8e90a302384561d24aef3e46
Autor:
Wong, Derek, Sogerer, Lisa, Lee, Samantha S., Wong, Victor, Lum, Amy, Levine, Adrian B., Marra, Marco A., Yip, Stephen
Additional file 2: Figure S2 ERK dysregulates CIC function. A) Representative Western blot of ATXN1LWT (NHA) and ATXN1LKO (B82) cell lines treated with FGF/EGF over 0-24 hours following serum starvation. FBS control was cultured in FBS for the durati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c8a58972c81085896d5b22e77f23afb
Autor:
Wong, Derek, Sogerer, Lisa, Lee, Samantha S., Wong, Victor, Lum, Amy, Levine, Adrian B., Marra, Marco A., Yip, Stephen
Additional file 3: Figure S3 Validation of ERK-CIC interaction. A) Representative Western blot of GBM cells following serum starvation and EGF/FGF treatment (1 hour). B) Representative Western blot of GBM cells following serum starvation and EGF/FGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2990f64321aa7e6583ee2c1fa1664110
Autor:
Wong, Derek, Sogerer, Lisa, Lee, Samantha S., Wong, Victor, Lum, Amy, Levine, Adrian B., Marra, Marco A., Yip, Stephen
Additional file 3: Figure S3 Validation of ERK-CIC interaction. A) Representative Western blot of GBM cells following serum starvation and EGF/FGF treatment (1 hour). B) Representative Western blot of GBM cells following serum starvation and EGF/FGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3e158185e49416f0fe650cb233d4a20