Zobrazeno 1 - 10
of 724
pro vyhledávání: '"Lester Packer"'
Autor:
Robert L, Heath, Lester, Packer
Publikováno v:
Archives of Biochemistry and Biophysics. 726:109248
A photo-induced cyclic peroxidation in isolated chloroplasts is described. In an osmotic buffered medium, chloroplasts upon illumination produce malondialdehyde (MDA)-a decomposition product of tri-unsaturated fatty acid hydroperoxides-bleach endogen
Autor:
Sharon V. Landvik, Lester Packer
Publikováno v:
Antioxidant Status, Diet, Nutrition, and Health ISBN: 9780367811099
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdb936c82ef20f142b8d9a53db3199f8
https://doi.org/10.1201/9780367811099-26
https://doi.org/10.1201/9780367811099-26
Publikováno v:
Handbook of Synthetic Antioxidants ISBN: 9780367813543
Handbook of Synthetic Antioxidants
Handbook of Synthetic Antioxidants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5a40af024d6092bdd6086565b25fa74
https://doi.org/10.1201/9780367813543-7
https://doi.org/10.1201/9780367813543-7
Autor:
Lester Packer, Enrique Cadenas
General concepts: approach and rationale for the design of synthetic derivatives of natural antioxidants as therapeutic agents. Synthetic derivatives of natural antioxidants: design and biological evaluation of tissue-directed alpha-tocopherol analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a449b34f5b0a54b6f242e9eb1b786e7a
https://doi.org/10.1201/9780367813543
https://doi.org/10.1201/9780367813543
Publikováno v:
Redox report : communications in free radical research. 3(3)
Exposure of human plasma to gas-phase cigarette smoke (CS) causes loss of human plasma antioxidants, protein modification (Frei et al, Biochem J, 1991 277:133-138; Reznick et al, Biochem J, 1992 286: 607-611) and a minimal amount of lipid oxidation.
Autor:
Xianglin Shi, Wei-Jin Zang, Lester Packer, Jiankang Liu, Weili Shen, Zhihui Feng, Chuan Tian, Weijun Chen, Jiejie Hao
Publikováno v:
British Journal of Pharmacology. 162:1213-1224
BACKGROUND AND PURPOSE Metabolic dysfunction due to loss of mitochondria plays an important role in diabetes, and stimulation of mitochondrial biogenesis by anti-diabetic drugs improves mitochondrial function. In a search for potent stimulators of mi
Autor:
Lester Packer, Enrique Cadenas
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
The role of R-α-lipoic acid as a cofactor (lipoyllysine) in mitochondrial energy metabolism is well established. Lipoic acid non-covalently bound and exogenously administered to cells or supplemented in the diet is a potent modulator of the cell’s
Autor:
Xuesen Li, Carl W. Cotman, Jiankang Liu, Haiqun Jia, Bei Hou, Cheng Luo, Lester Packer, Lijuan Sun, Zhongbo Liu, Weili Shen
Publikováno v:
Free Radical Biology and Medicine. 44:1465-1474
alpha-Lipoic acid (LA) has been widely studied as an agent for preventing and treating various diseases associated with oxidative disruption of mitochondrial functions. To investigate a related mitochondrial antioxidant, we compared the effects of li
Autor:
J. Ren, Lester Packer, L. Yang, C. W. Cotman, Jiankang Liu, Xuesen Li, Kai Liu, Weili Shen, C. Tian
Publikováno v:
Diabetologia. 51:165-174
The aim of the study was to address the importance of mitochondrial function in insulin resistance and type 2 diabetes, and also to identify effective agents for ameliorating insulin resistance in type 2 diabetes. We examined the effect of two mitoch
Publikováno v:
Journal of Gastroenterology and Hepatology. 22:697-703
Background and Aim: Oxidative DNA damage occurs as an early event in hepatitis C virus (HCV) infection and is an indication of the potential for carcinogenesis. The aim of this study was to test a novel antioxidant/immunomodulator in patients with HC