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of 8
pro vyhledávání: '"Karn, Jonathan"'
Autor:
Joussef-Pi��a, Samira, Nankya, Immaculate, Nalukwago, Sophie, Baseke, Joy, Rwambuya, Sandra, Winner, Dane, Kyeyune, Fred, Chervenak, Keith, Thiel, Bonnie, Asaad, Robert, Dobrowolski, Curtis, Luttge, Benjamin, Lawley, Blair, Kityo, Cissy M., Boom, W. Henry, Karn, Jonathan, Qui��ones-Mateu, Miguel E.
Additional file 8: Figure S7. Size of the inducible peripheral HIV-1 reservoir in male and female HIV-infected individuals from Uganda (n = 62) and the U.S. (n =50) estimated by measuring cell-associated spliced HIV-1 RNA (EDITS assay) and proviral D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a43aeab724f7347189e5cf9ba7ede5
Autor:
Joussef-Pi��a, Samira, Nankya, Immaculate, Nalukwago, Sophie, Baseke, Joy, Rwambuya, Sandra, Winner, Dane, Kyeyune, Fred, Chervenak, Keith, Thiel, Bonnie, Asaad, Robert, Dobrowolski, Curtis, Luttge, Benjamin, Lawley, Blair, Kityo, Cissy M., Boom, W. Henry, Karn, Jonathan, Qui��ones-Mateu, Miguel E.
Additional file 3: Figure S2. Sensitivity of EDITS primers. A Nested PCR primers nF6026 and nR6773 were evaluated using a serial dilution of DNA from the HIV-1 molecular clone pNL4-3 (0% to 100%) in a background of DNA from the non-HIV plasmid pUC19,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e72f1694958c651d694e74da3cf7e2d
Autor:
Joussef-Pi��a, Samira, Nankya, Immaculate, Nalukwago, Sophie, Baseke, Joy, Rwambuya, Sandra, Winner, Dane, Kyeyune, Fred, Chervenak, Keith, Thiel, Bonnie, Asaad, Robert, Dobrowolski, Curtis, Luttge, Benjamin, Lawley, Blair, Kityo, Cissy M., Boom, W. Henry, Karn, Jonathan, Qui��ones-Mateu, Miguel E.
Additional file 4: Figure S3. Analytical sensitivity of the EDITS assay. Jurkat E4, a cell line latently infected with a single copy of HIV-1 per cell, and Jurkat E6-1, an HIV-negative human T cell lymphoblast, were quantified and serial dilutions we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8b7fe3088c3091db54cc431975b77f
Autor:
Joussef-Pi��a, Samira, Nankya, Immaculate, Nalukwago, Sophie, Baseke, Joy, Rwambuya, Sandra, Winner, Dane, Kyeyune, Fred, Chervenak, Keith, Thiel, Bonnie, Asaad, Robert, Dobrowolski, Curtis, Luttge, Benjamin, Lawley, Blair, Kityo, Cissy M., Boom, W. Henry, Karn, Jonathan, Qui��ones-Mateu, Miguel E.
Additional file 7: Figure S6. Quantification of number of cells used in the EDITS assay. Cellular DNA was extracted from one million memory CD4+ T cells purified from 15 Ugandan and 25 U.S. patients, as well as one million Jurkat E4 (HIV+)/Jurkat E^-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419a6ee0968d04fca45dc12d4a1b3101
Autor:
Joussef-Pi��a, Samira, Nankya, Immaculate, Nalukwago, Sophie, Baseke, Joy, Rwambuya, Sandra, Winner, Dane, Kyeyune, Fred, Chervenak, Keith, Thiel, Bonnie, Asaad, Robert, Dobrowolski, Curtis, Luttge, Benjamin, Lawley, Blair, Kityo, Cissy M., Boom, W. Henry, Karn, Jonathan, Qui��ones-Mateu, Miguel E.
Additional file 6: Figure S5. Relevant metrics generated during each one of the deep sequencing runs corresponding to the EDITS assay and/or the proviral DNA test. Number of samples included in each specific MiSeq run. Clusters Passing Filter (Cluste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cd7a89462f7725460dab871ce885d1
Autor:
Joussef-Pi��a, Samira, Nankya, Immaculate, Nalukwago, Sophie, Baseke, Joy, Rwambuya, Sandra, Winner, Dane, Kyeyune, Fred, Chervenak, Keith, Thiel, Bonnie, Asaad, Robert, Dobrowolski, Curtis, Luttge, Benjamin, Lawley, Blair, Kityo, Cissy M., Boom, W. Henry, Karn, Jonathan, Qui��ones-Mateu, Miguel E.
Additional file 2: Figure S1. Specificity of EDITS primers. A Thirty-two HIV-1 group M isolates, as well as eight RNA or DNA viruses (BKV, BK virus; CMV, Cytomegalovirus; HSV-1 and HSV-2, Herpes simplex virus 1 and 2; VZV, Varicella zoster virus; HBV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015a629368ff6dbc5fa6091ddafc9752
Autor:
Joussef-Pi��a, Samira, Nankya, Immaculate, Nalukwago, Sophie, Baseke, Joy, Rwambuya, Sandra, Winner, Dane, Kyeyune, Fred, Chervenak, Keith, Thiel, Bonnie, Asaad, Robert, Dobrowolski, Curtis, Luttge, Benjamin, Lawley, Blair, Kityo, Cissy M., Boom, W. Henry, Karn, Jonathan, Qui��ones-Mateu, Miguel E.
Additional file 5: Figure S4. Validation of the EDITS assay. Memory CD4+ T cells from five ART-experienced, well-suppressed (plasma HIV-1 RNA load < 20 copies/ml) individuals infected with HIV-1 subtype B strains in Cleveland, OH were used to quantif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e18e6e4c30d1bd2d0852885c01bb295
Autor:
Barker, Edward, Planelles, Vicente, Karn, Jonathan, Garrido, Carolina, Margolis, David M., Soriano-Sarabia, Natalia, Checkley, Mary Ann, Spivak, Adam M.
In an effort to clear persistent HIV infection and achieve a durable therapy-free remission of HIV disease, extensive pre-clinical studies and early pilot clinical trials are underway to develop and test agents that can reverse latent HIV infection a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a21eefc82dce872ff1acb13e52d5add