Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Joan J. Guinovart"'
Publikováno v:
Frontiers in Endocrinology. 13
Increased liver glycogen content has been shown to reduce food intake, attenuate obesity, and improve glucose tolerance in a mouse model of high-fat diet (HFD)-induced obesity. Here we studied the contribution of liver glycogen to the regulation of o
Autor:
Gokhan Uruk, Sinem Yilmaz-Ozcan, Canan Cakir-Aktas, Aslihan Taskiran-Sag, Buket Donmez-Demir, Jordi Duran, Joan J. Guinovart, Hulya Karatas-Kurşun, Turgay Dalkara, Muge Yemisci
Ischemic stroke results in sudden blood flow cessation, thus, unmet energy requirements. Although the clotted artery can be recanalized and blood flow is restored, brain perfusion may not be fully attained due to microvascular constrictions. Under gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8527cefbd893f01b6a6c1e59f7cc7f5f
https://doi.org/10.1101/2022.08.24.505172
https://doi.org/10.1101/2022.08.24.505172
Autor:
Jordi Duran, Giorgia Testoni, Elena Lopez-Rodriguez, María Isabel Hernández-Álvarez, Joan J. Guinovart, Mònica Aguilera, Neus Prats, Bárbara Olmeda, Jesús Pérez-Gil
Publikováno v:
Human Molecular Genetics. 29:3554-3565
The glycogenin knockout mouse is a model of Glycogen Storage Disease type XV. These animals show high perinatal mortality (90%) due to respiratory failure. The lungs of glycogenin-deficient embryos and P0 mice have a lower glycogen content than that
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2574
Volume 24
Issue 3
Pages: 2574
Many lines of evidence demonstrate a correlation between liver glycogen content and food intake. We previously demonstrated that mice overexpressing protein targeting to glycogen (PTG) specifically in the liver—which have increased glycogen content
Autor:
Sinthu Pathmanapan, Raymond Poon, Tomasa Barrientos De Renshaw, Puviindran Nadesan, Makoto Nakagawa, Gireesh A. Seesankar, Adrian Kwan Ho Loe, Hongyuan H. Zhang, Joan J. Guinovart, Jordi Duran, Christopher B. Newgard, Jay S. Wunder, Benjamin A. Alman
Publikováno v:
SSRN Electronic Journal.
Autor:
Pasquale Pellegrini, Arnau Hervera, Olga Varea, M. Kathryn Brewer, Iliana López-Soldado, Anna Guitart, Mònica Aguilera, Neus Prats, José Antonio del Río, Joan J. Guinovart, Jordi Duran
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Lafora disease (LD) is a fatal childhood-onset dementia characterized by the extensive accumulation of glycogen aggregates—the so-called Lafora Bodies (LBs)—in several organs. The accumulation of LBs in the brain underlies the neurological phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362d2484d9db89b88eb55a0eda93217d
http://hdl.handle.net/2445/189692
http://hdl.handle.net/2445/189692
Publikováno v:
Brain communications. 4(4)
Lafora disease is a fatal neurodegenerative childhood dementia caused by loss-of-function mutations in either the laforin or malin gene. The hallmark of the disease is the accumulation of abnormal glycogen aggregates known as Lafora bodies (LBs) in t
Autor:
Joan J. Guinovart, Muriel Arimon
Publikováno v:
Biochemistry and Molecular Biology Education. 48:559-562
The Institute for Research in Biomedicine (IRB Barcelona) is a world-class research center devoted to understanding fundamental questions about human health and disease. In addition to conducting multidisciplinary research of excellence, IRB Barcelon
Publikováno v:
FEBS Lett
Glycogen shortage during fasting coincides with dramatic changes in hepatic adenine nucleotide levels. The aim of this work was to study the relevance of liver glycogen in the regulation of the hepatic energy state during food deprivation. To this en
Autor:
del Rio Ja, Brewer Mk, Jordi Duran, Prat N, López-Soldado I, Pellegrini P, Varea O, Joan J. Guinovart, Guitart A, Arnau Hervera, Aguilera M
BackgroundLafora disease (LD) is a fatal childhood-onset dementia characterized by the extensive accumulation of glycogen aggregates—the so-called Lafora Bodies (LBs)—in several organs. The accumulation of LBs in the brain underlies the neurologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba4310a229fb376b919f0cedb9172e6c
https://doi.org/10.1101/2021.06.03.446965
https://doi.org/10.1101/2021.06.03.446965