Zobrazeno 91 - 100
of 197
pro vyhledávání: '"Joan J. Guinovart"'
Autor:
Monique Beullens, Bruno Guigas, Alexander von Wilamowitz-Moellendorff, Mark H. Rider, Kei Sakamoto, Liliane Maisin, Joan J. Guinovart, Louis Hue, Nusrat Hussain, Didier Vertommen, Marc Foretz, Benoit Viollet, Laurent Bultot
Publikováno v:
Biochemical Journal, 443, 193-203
Recombinant muscle GYS1 (glycogen synthase 1) and recombinant liver GYS2 were phosphorylated by recombinant AMPK (AMP-activated protein kinase) in a time-dependent manner and to a similar stoichiometry. The phosphorylation site in GYS2 was identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1295ece1555a9a75f353f2bc5b0e93a
https://hdl.handle.net/1887/111301
https://hdl.handle.net/1887/111301
Publikováno v:
RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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[EN] Tungstate counteracts diabetes and obesity in animal models, but its molecular mechanisms remain elusive. Our Saccharomyces cerevisiae-based approach has found that tungstate alleviated the growth defect induced by nutrient stress and enhanced t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ace26220c612e237d5b88f873a9457
http://hdl.handle.net/10251/78514
http://hdl.handle.net/10251/78514
Publikováno v:
Metabolites
Repositori Institucional de la Universitat Rovira i Virgili
Universitat Rovira i virgili (URV)
Metabolites, Vol 2, Iss 4, Pp 775-795 (2012)
Repositori Institucional de la Universitat Rovira i Virgili
Universitat Rovira i virgili (URV)
Metabolites, Vol 2, Iss 4, Pp 775-795 (2012)
doi:10.3390/metabo2040775 Several metabolomic software programs provide methods for peak picking, retention time alignment and quantification of metabolite features in LC/MS-based metabolomics. Statistical analysis, however, is needed in order to dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c735d698725d1f4c322517a27d26138d
http://hdl.handle.net/20.500.11797/PC226
http://hdl.handle.net/20.500.11797/PC226
Publikováno v:
Biochemical Journal. 304:449-453
The ability of amylin to impair hepatic insulin action is controversial. We have found that the effect of amylin in primary cultured hepatocytes is strongly dependent on the culture conditions. Only in hepatocytes preincubated in the presence of feta
Publikováno v:
Biochemistry and Molecular Biology Education. 30:172-174
This manuscript describes a new strategy for introducing secondary school students to biochemistry. To bridge the gap between secondary education and the university, the Department of Biochemistry and Molecular Biology of the University of Barcelona,
Autor:
Jordi Duran, Joan J. Guinovart, Maria Florencia Tevy, Joaquim Calbó, Marco Milán, Mar García-Rocha
Publikováno v:
EMBO Molecular Medicine
Under physiological conditions, most neurons keep glycogen synthase (GS) in an inactive form and do not show detectable levels of glycogen. Nevertheless, aberrant glycogen accumulation in neurons is a hallmark of patients suffering from Lafora diseas
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Glycogen synthase, a central enzyme in glucose metabolism, catalyzes the successive addition of α-1,4-linked glucose residues to the non-reducing end of a growing glycogen molecule. A non-catalytic glycogen-binding site, identified by x-ray crysta
Autor:
Nuria Rodríguez-Fariñas, M. Milagros Gómez-Gómez, Joan J. Guinovart, Jorge Domínguez, Carmen Camara-Rica, Benito Cañas-Montalvo
Publikováno v:
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
E-Prints Complutense. Archivo Institucional de la UCM
instname
Universidad Complutense de Madrid
E-Prints Complutense. Archivo Institucional de la UCM
instname
It is known that oral administration of sodium tungstate preserves the pancreatic beta cell function in diabetic rats. Healthy and streptozotocin-induced diabetic rats were treated with sodium tungstate for one, three or six weeks, after which the sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3469ada788de0cfc766951c6da913e26
Publikováno v:
Microorganisms in Industry and Environment.
We have developed a 2-day lab-practice to present microbiology and biotechnology to science secondary school students. This initiative seeks to familiarize students with microbial physiology and fermentation technology and to stimulate debate between
Autor:
Susana Ros, Delia Zafra, Stephen Forrow, Jordi Valles-Ortega, Joan J. Guinovart, Mar García-Rocha, Jorge Domínguez, Joaquim Calbó
Publikováno v:
The Journal of biological chemistry. 285(48)
In this study, we tested the efficacy of increasing liver glycogen synthase to improve blood glucose homeostasis. The overexpression of wild-type liver glycogen synthase in rats had no effect on blood glucose homeostasis in either the fed or the fast