Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jessica Sudderth"'
Autor:
Michael A. White, Ralf Kittler, Georgina V. Long, Helen Rizos, Lynda Chin, Noelle S. Williams, Jef K. De Brabander, Yonghao Yu, Jennifer A. Wargo, Michael A. Davies, Claudia Wellbrock, Ralph J. Deberardinis, Kakajan Komurov, Jessica Sudderth, Michael P. Smith, Ugur Eskiocak, Tracy I. Rosales, Aubhishek Zaman, Ming Ding, Jose Garcia-Rodriguez, Changguang Wang, Caroline G. Humphries, Hailei Zhang, Rahul K. Kollipara, Saurabh Mendiratta, Elizabeth A. McMillan, Banu Eskiocak
Extended Experimental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1039b26720af4f97108c00b1b555a8ab
https://doi.org/10.1158/2159-8290.22531921.v1
https://doi.org/10.1158/2159-8290.22531921.v1
Autor:
Michael A. White, Ralf Kittler, Georgina V. Long, Helen Rizos, Lynda Chin, Noelle S. Williams, Jef K. De Brabander, Yonghao Yu, Jennifer A. Wargo, Michael A. Davies, Claudia Wellbrock, Ralph J. Deberardinis, Kakajan Komurov, Jessica Sudderth, Michael P. Smith, Ugur Eskiocak, Tracy I. Rosales, Aubhishek Zaman, Ming Ding, Jose Garcia-Rodriguez, Changguang Wang, Caroline G. Humphries, Hailei Zhang, Rahul K. Kollipara, Saurabh Mendiratta, Elizabeth A. McMillan, Banu Eskiocak
Supplemental Figure S1. Integrative Analysis of Functional Genomics and Copy Number Variation in Melanoma Cells and Tissues, Supplemental Figure S2. Elastic Net Derived Biomarker Results for Melanoma Survival Genes and Detection of These Biomarkers i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2582c174f25f18c51c5ccc75c043f0
https://doi.org/10.1158/2159-8290.22531915
https://doi.org/10.1158/2159-8290.22531915
Autor:
Ralph J. DeBerardinis, Jeffrey G. McDonald, Robert G. Bachoo, Tuyen Dang, Jessica Sudderth, Chendong Yang
Supplementary Methods, Figures 1-5, Table 1 from Glioblastoma Cells Require Glutamate Dehydrogenase to Survive Impairments of Glucose Metabolism or Akt Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d2ccb02d6af762cbb053967653ae43
https://doi.org/10.1158/0008-5472.22382300
https://doi.org/10.1158/0008-5472.22382300
Autor:
Ralph J. DeBerardinis, Jeffrey G. McDonald, Robert G. Bachoo, Tuyen Dang, Jessica Sudderth, Chendong Yang
Oncogenes influence nutrient metabolism and nutrient dependence. The oncogene c-Myc stimulates glutamine metabolism and renders cells dependent on glutamine to sustain viability (“glutamine addiction”), suggesting that treatments targeting glutam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d44ea5a8cc9dfa9cd74d4c51b0940f
https://doi.org/10.1158/0008-5472.c.6500156
https://doi.org/10.1158/0008-5472.c.6500156
Autor:
Kenneth E. Huffman, Long Shan Li, Ryan Carstens, Hyunsil Park, Luc Girard, Kimberley Avila, Shuguang Wei, Rahul Kollipara, Brenda Timmons, Jessica Sudderth, Nawal Bendris, Jiyeon Kim, Pamela Villalobos, Junya Fujimoto, Sandra Schmid, Ralph J. Deberardinis, Ignacio Wistuba, John Heymach, Ralf Kittler, Esra A. Akbay, Bruce Posner, Yuzhuo Wang, Stephen Lam, Steven A. Kliewer, David J. Mangelsdorf, John D. Minna
Publikováno v:
Frontiers in Oncology. 13
The glucocorticoid receptor (GR) is an important anti-cancer target in lymphoid cancers but has been understudied in solid tumors like lung cancer, although glucocorticoids are often given with chemotherapy regimens to mitigate side effects. Here, we
Autor:
Sarah MacPherson, Sarah Keyes, Marisa K. Kilgour, Julian Smazynski, Vanessa Chan, Jessica Sudderth, Tim Turcotte, Adria Devlieger, Jessie Yu, Kimberly S. Huggler, Jason R. Cantor, Ralph J. DeBerardinis, Christopher Siatskas, Julian J. Lum
Publikováno v:
Molecular Therapy - Methods & Clinical Development. 24:380-393
Autor:
Divya Bezwada, Nicholas P. Lesner, Bailey Brooks, Hieu S. Vu, Zheng Wu, Ling Cai, Stacy Kasitinon, Sherwin Kelekar, Feng Cai, Arin B. Aurora, McKenzie Patrick, Ashley Leach, Rashed Ghandour, Yuanyuan Zhang, Duyen Do, Jessica Sudderth, Dennis Dumesnil, Sara House, Tracy Rosales, Alan M. Poole, Yair Lotan, Solomon Woldu, Aditya Bagrodia, Xiaosong Meng, Jeffrey A. Cadeddu, Prashant Mishra, Ivan Pedrosa, Payal Kapur, Kevin D. Courtney, Craig R. Malloy, Vitaly Margulis, Ralph J. DeBerardinis
Publikováno v:
bioRxiv
SummaryMost kidney cancers display evidence of metabolic dysfunction1–4but how this relates to cancer progression in humans is unknown. We used a multidisciplinary approach to infuse13C-labeled nutrients during surgical tumour resection in over 70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6d2448d68a99890c9685f4d79bf794
https://doi.org/10.1101/2023.02.06.527285
https://doi.org/10.1101/2023.02.06.527285
Autor:
Panayotis Pachnis, Zheng Wu, Brandon Faubert, Alpaslan Tasdogan, Wen Gu, Spencer Shelton, Ashley Solmonson, Aparna D. Rao, Akash K. Kaushik, Thomas J. Rogers, Jessalyn M. Ubellacker, Collette A. LaVigne, Chendong Yang, Bookyung Ko, Vijayashree Ramesh, Jessica Sudderth, Lauren G. Zacharias, Misty S. Martin-Sandoval, Duyen Do, Thomas P. Mathews, Zhiyu Zhao, Prashant Mishra, Sean J. Morrison, Ralph J. DeBerardinis
Publikováno v:
Science advances. 8(35)
In mice and humans with cancer, intravenous 13 C-glucose infusion results in 13 C labeling of tumor tricarboxylic acid (TCA) cycle intermediates, indicating that pyruvate oxidation in the TCA cycle occurs in tumors. The TCA cycle is usually coupled t
Autor:
Pravat Kumar Parida, Mauricio Marquez-Palencia, Akash K. Kaushik, Kangsan Kim, Vidhya Nair, Jessica Sudderth, Hieu Vu, Lauren Zacharias, Ralph DeBerardinis, Srinivas Malladi
Publikováno v:
STAR protocols. 3(2)
Analyzing the metabolic dependencies of tumor cells is vital for cancer diagnosis and treatment. Here, we describe a protocol for
Autor:
Julian Smazynski, Kimberly S. Huggler, Jessica Sudderth, Adria Devlieger, Ralph J. DeBerardinis, Tim Turcotte, Marisa Kilgour, Christopher Siatskas, Sarah MacPherson, Sarah Keyes, Jason R. Cantor, Jessie Yu, Julian J. Lum
Ex vivo expansion conditions used to generate T cells for immunotherapy are thought to adopt metabolic phenotypes that impede therapeutic efficacy in vivo. The comparison of five different culture media used for clinical T cell expansion revealed uni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4c1e9afdbfe1e024d7ee7e1bed12e8d
https://doi.org/10.1101/2021.08.24.457536
https://doi.org/10.1101/2021.08.24.457536