Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Hugues Aschard"'
Autor:
Stéphanie Pons, Fabrice Uhel, Eric Frapy, Youssouf Sérémé, Lara Zafrani, Hugues Aschard, David Skurnik
Publikováno v:
Stem Cell Reviews and Reports
Stem Cell Reviews and Reports, 2023, 19 (3), pp.585-600. ⟨10.1007/s12015-022-10477-y⟩
Stem Cell Reviews and Reports, 2023, 19 (3), pp.585-600. ⟨10.1007/s12015-022-10477-y⟩
Since the beginning of the Coronavirus disease (COVID)-19 pandemic in December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been responsible for more than 600 million infections and 6.5 million deaths worldwide. Given th
Autor:
Brian M. Wolpin, Charles S. Fuchs, JoAnn E. Manson, Juhua Luo, Barbara B. Cochrane, Matthew L. Anderson, Michael N. Pollak, Nader Rifai, John Michael Gaziano, Howard D. Sesso, Julie E. Buring, Shuji Ogino, Meir J. Stampfer, Kimmie Ng, Vicente Morales-Oyarvide, Rachael Stolzenberg-Solomon, Laufey T. Amundadottir, Peter Kraft, Hugues Aschard, Edward L. Giovannucci, Chen Yuan, Zhi Rong Qian, Ying Bao, Ana Babic
Supplementary Table 1. Number of pancreatic cancer cases by cohort with available plasma leptin levels and genotyped SNPs at LEPR Supplementary Table 2. Characteristics of controls from five prospective cohorts Supplementary Table 3. Partial Spearman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbaa0be131f10089034e10f9807e1f7
https://doi.org/10.1158/0008-5472.22412694.v1
https://doi.org/10.1158/0008-5472.22412694.v1
Autor:
Brian M. Wolpin, Charles S. Fuchs, JoAnn E. Manson, Juhua Luo, Barbara B. Cochrane, Matthew L. Anderson, Michael N. Pollak, Nader Rifai, John Michael Gaziano, Howard D. Sesso, Julie E. Buring, Shuji Ogino, Meir J. Stampfer, Kimmie Ng, Vicente Morales-Oyarvide, Rachael Stolzenberg-Solomon, Laufey T. Amundadottir, Peter Kraft, Hugues Aschard, Edward L. Giovannucci, Chen Yuan, Zhi Rong Qian, Ying Bao, Ana Babic
Leptin is an adipokine involved in regulating energy balance, which has been identified as a potential biologic link in the development of obesity-associated cancers, such as pancreatic cancer. In this prospective, nested case–control study of 470
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3959b0c29cfa9ceb604f6e027c4c0d64
https://doi.org/10.1158/0008-5472.c.6508494.v1
https://doi.org/10.1158/0008-5472.c.6508494.v1
Autor:
Tristan Hoellinger, Camille Mestre, Hugues Aschard, Wilfried Le Goff, Sylvain Foissac, Thomas Faraut, Sarah Djebali
Publikováno v:
Frontiers in Bioinformatics
Frontiers in Bioinformatics, 2023, 3, pp.1092853. ⟨10.3389/fbinf.2023.1092853⟩
Frontiers in Bioinformatics, 2023, 3, pp.1092853. ⟨10.3389/fbinf.2023.1092853⟩
Differences in cells’ functions arise from differential activity of regulatory elements, including enhancers. Enhancers are cis-regulatory elements that cooperate with promoters through transcription factors to activate the expression of one or sev
Autor:
Andrey Ziyatdinov, Brian D. Hobbs, Samir Kanaan-Izquierdo, Matthew Moll, Phuwanat Sakornsakolpat, Nick Shrine, Jing Chen, Kijoung Song, Russell P. Bowler, Peter J. Castaldi, Martin D. Tobin, Peter Kraft, Edwin K. Silverman, Hanna Julienne, Hugues Aschard, Michael H. Cho
Publikováno v:
medRxiv
Chronic Obstructive Pulmonary Disease (COPD) has a simple physiological diagnostic criterion but a wide range of clinical characteristics. The mechanisms underlying this variability in COPD phenotypes are unclear. To investigate the potential contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe352a00dfac9c7579f4271fc3afb47
https://doi.org/10.1101/2023.02.20.23286186
https://doi.org/10.1101/2023.02.20.23286186
Autor:
Kelsey V. Stuart, Robert N. Luben, Alasdair N. Warwick, Kian M. Madjedi, Praveen J. Patel, Mahantesh I. Biradar, Zihan Sun, Mark A. Chia, Louis R. Pasquale, Janey L. Wiggs, Jae H. Kang, Jihye Kim, Hugues Aschard, Jessica H. Tran, Marleen A.H. Lentjes, Paul J. Foster, Anthony P. Khawaja, Mark Chia, Sharon Chua, Ron Do, Paul Foster, Jae Kang, Alan Kastner, Anthony Khawaja, Marleen Lentjes, Robert Luben, Kian Madjedi, Giovanni Montesano, Louis Pasquale, Kelsey Stuart, Alasdair Warwick, Janey Wiggs, Naomi Allen, Tariq Aslam, Denize Atan, Sarah Barman, Jenny Barrett, Paul Bishop, Graeme Black, Tasanee Braithwaite, Roxana Carare, Usha Chakravarthy, Michelle Chan, Alexander Day, Parul Desai, Bal Dhillon, Andrew Dick, Alexander Doney, Cathy Egan, Sarah Ennis, Marcus Fruttiger, John Gallacher, David (Ted) Garway-Heath, Jane Gibson, Jeremy Guggenheim, Chris Hammond, Alison Hardcastle, Simon Harding, Ruth Hogg, Pirro Hysi, Pearse Keane, Peng Tee Khaw, Gerassimos Lascaratos, Thomas Littlejohns, Andrew Lotery, Phil Luthert, Tom MacGillivray, Sarah Mackie, Bernadette McGuinness, Gareth McKay, Martin McKibbin, Tony Moore, James Morgan, Eoin O'Sullivan, Richard Oram, Chris Owen, Praveen Patel, Euan Paterson, Tunde Peto, Axel Petzold, Nikolas Pontikos, Jugnoo Rahi, Alicja Rudnicka, Naveed Sattar, Jay Self, Panagiotis Sergouniotis, Sobha Sivaprasad, David Steel, Irene Stratton, Nicholas Strouthidis, Cathie Sudlow, Robyn Tapp, Dhanes Thomas, Emanuele Trucco, Adnan Tufail, Ananth Viswanathan, Veronique Vitart, Mike Weedon, Katie Williams, Cathy Williams, Jayne Woodside, Max Yates, Jennifer Yip, Yalin Zheng, Tin Aung, Kathryn Burdon, Li Chen, Ching-Yu Cheng, Jamie Craig, Angela Cree, Victor de Vries, Sjoerd Driessen, John Fingert, Puya Gharahkhani, Christopher Hammond, Caroline Hayward, Alex Hewitt, Nomdo Jansonius, Fridbert Jonansson, Jost Jonas, Michael Kass, Chiea Khor, Caroline Klaver, Jacyline Koh, Stuart MacGregor, David Mackey, Paul Mitchell, Calvin Pang, Francesca Pasutto, Norbert Pfeiffer, Ozren Polašek, Wishal Ramdas, Alexander Schuster, Ayellet Segrè, Einer Stefansson, Kári Stefánsson, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Cornelia van Duijn, Joëlle Vergroesen, Eranga Vithana, James Wilson, Robert Wojciechowski, Tien Wong, Terri Young
Publikováno v:
Ophthalmology Glaucoma.
Autor:
Celine Posseme, Alba Llibre, Bruno Charbit, Vincent Bondet, Vincent Rouilly, Violaine Saint-André, Jeremy Boussier, Jacob Bergstedt, Nikaïa Smith, Liam Townsend, Jamie A. Sugrue, Clíona Ní Cheallaigh, Niall Conlon, Maxime Rotival, Michael S. Kobor, Estelle Mottez, Stanislas Pol, Etienne Patin, Matthew L. Albert, Lluis Quintana-Murci, Darragh Duffy, Laurent Abel, Andres Alcover, Hugues Aschard, Philippe Bousso, Nollaig Bourke, Petter Brodin, Pierre Bruhns, Nadine Cerf-Bensussan, Ana Cumano, Caroline Demangel, null Christophe d’Enfert, Ludovic Deriano, Marie-Agnès Dillies, James Di Santo, Françoise Dromer, Gérard Eberl, Jost Enninga, Jacques Fellay, Ivo Gomperts-Boneca, Milena Hasan, Magnus Fontes, Gunilla Karlsson Hedestam, Serge Hercberg, Molly A. Ingersoll, Rose Anne Kenny, Olivier Lantz, Mickael Ménager, Frédérique Michel, Hugo Mouquet, Cliona O'Farrelly, Sandra Pellegrini, Antonio Rausell, Frédéric Rieux-Laucat, Lars Rogge, Anavaj Sakuntabhai, Olivier Schwartz, Benno Schwikowski, Spencer Shorte, Frédéric Tangy, Antoine Toubert, Mathilde Touvier, Marie-Noëlle Ungeheuer, Christophe Zimmer
Publikováno v:
Cell Reports
Cell Reports, 2022, 39 (13), pp.110989. ⟨10.1016/j.celrep.2022.110989⟩
Cell Reports, 2022, ⟨10.1016/j.celrep.2022.110989⟩
Cell Reports, 2022, 39 (13), pp.110989. ⟨10.1016/j.celrep.2022.110989⟩
Cell Reports, 2022, ⟨10.1016/j.celrep.2022.110989⟩
International audience; The interleukin-12 (IL-12) family comprises the only heterodimeric cytokines mediating diverse functional effects. We previously reported a striking bimodal IL-12p70 response to lipopolysaccharide (LPS) stimulation in healthy
Autor:
Kelsey V, Stuart, Robert N, Luben, Alasdair N, Warwick, Kian M, Madjedi, Praveen J, Patel, Mahantesh I, Biradar, Zihan, Sun, Mark A, Chia, Louis R, Pasquale, Janey L, Wiggs, Jae H, Kang, Jihye, Kim, Hugues, Aschard, Jessica H, Tran, Marleen A H, Lentjes, Paul J, Foster, Anthony P, Khawaja
Publikováno v:
Ophthalmology. Glaucoma.
To examine the associations of alcohol consumption with glaucoma and related traits; to assess whether a genetic predisposition to glaucoma modified these associations; and to perform Mendelian randomization (MR) experiments to probe causal effects.C
Autor:
Nicolas Bourgon, Wendy Fitzgerald, Hugues Aschard, Jean-François Magny, Tiffany Guilleminot, Julien Stirnemann, Roberto Romero, Yves Ville, Leonid Margolis, Marianne Leruez-Ville
Publikováno v:
Viruses; Volume 14; Issue 10; Pages: 2145
Viruses
Viruses, 2022, 14 (10), pp.2145. ⟨10.3390/v14102145⟩
Viruses
Viruses, 2022, 14 (10), pp.2145. ⟨10.3390/v14102145⟩
International audience; Background: Congenital cytomegalovirus (cCMV) infection is frequent and potentially severe. The immunobiology of cCMV infection is poorly understood, involving cytokines that could be carried within or on the surface of extrac
Autor:
Clara Albiñana, Zhihong Zhu, Andrew J. Schork, Andrés Ingason, Hugues Aschard, Isabell Brikell, Cynthia M. Bulik, Liselotte V. Petersen, Esben Agerbo, Jakob Grove, Merete Nordentoft, David M. Hougaard, Thomas Werge, Anders D. Børglum, Preben Bo Mortensen, John J. McGrath, Benjamin M. Neale, Florian Privé, Bjarni J. Vilhjálmsson
Publikováno v:
Nature Communications
Nature Communications, In press
Nature Communications, In press
The predictive performance of polygenic scores (PGS) is largely dependent on the number of samples available to train the PGS. Increasing the sample size for a specific phenotype is expensive and takes time, but this sample size can be effectively in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b21d586f15a96eda3cf6aee756e6cf
https://doi.org/10.1101/2022.09.14.22279940
https://doi.org/10.1101/2022.09.14.22279940