Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hemann, Michael T."'
Autor:
Jiang, Tingting, Sánchez-Rivera, Francisco J., Soto-Feliciano, Yadira M., Yang, Qiyuan, Song, Chun-Qing, Bhuatkar, Arjun, Haynes, Cole M, Hemann, Michael T., Xue, Wen
Publikováno v:
Hepatology
Hepatocellular carcinoma (HCC) is among the most common cancer types worldwide; yet, patients with HCC have limited treatment options. There is an urgent need to identify new drug targets that specifically inhibit the growth of HCC cells. Here, we us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e4306e66212fb9fda0779282054f6b2
https://europepmc.org/articles/PMC8209110/
https://europepmc.org/articles/PMC8209110/
Autor:
Murai, Junko, Pommier, Yves, Hemann, Michael T, Bruno, Peter Michael, Liu, Yunpeng, Park, Ga Young, Koch, Catherine E., Lippard, Stephen J., Hemann, Michael, Eisen, Timothy Jonas, Pritchard, Justin R.
Publikováno v:
PMC
Cisplatin and its platinum analogs, carboplatin and oxaliplatin, are some of the most widely used cancer chemotherapeutics. Although cisplatin and carboplatin are used primarily in germ cell, breast and lung malignancies, oxaliplatin is instead used
Autor:
Braun, Christian J., Stanciu, Monica, Boutz, Paul L., Patterson, Jesse C., Calligaris, David, Higuchi, Fumi, Neupane, Rachit, Fenoglio, Silvia, Cahill, Daniel P., Wakimoto, Hiroaki, Agar, Nathalie Y.R., Yaffe, Michael B., Sharp, Phillip A., Hemann, Michael T., Lees, Jacqueline A., Boutz, Paul, Patterson, Jesse C, Yaffe, Michael B, Hemann, Michael, Lees, Jacqueline, Braun, Christian Joerg
Publikováno v:
PMC
Glioblastoma (GBM) is a devastating malignancy with few therapeutic options. We identify PRMT5 in an in vivo GBM shRNA screen and show that PRMT5 knockdown or inhibition potently suppresses in vivo GBM tumors, including patient-derived xenografts. Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e210e5c53eb396078136a098d2550e82
https://orcid.org/0000-0002-2598-0098
https://orcid.org/0000-0002-2598-0098
Autor:
Doles, Jason, Hemann, Michael T.
While microtubule poisons are commonly used for the treatment of diverse malignancies, relatively little is known about cellular factors that determine the relative efficacy of these drugs. Here, we identified the NIMA kinase, Nek4, in a genetic scre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5fca7fcabcb35fba394c1d955eea1bae
https://europepmc.org/articles/PMC2946156/
https://europepmc.org/articles/PMC2946156/