Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gupton, Stephanie L."'
Autor:
Winkle, Cortney C., Taylor, Kendra L., Dent, Erik W., Gallo, Gianluca, Greif, Karen F., Gupton, Stephanie L.
The generation of axon collateral branches is a fundamental aspect of the development of the nervous system and the response of axons to injury. Although much has been discovered about the signaling pathways and cytoskeletal dynamics underlying branc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a77098f8829b92f85df82a5ce6f9a0ca
https://europepmc.org/articles/PMC5079834/
https://europepmc.org/articles/PMC5079834/
Autor:
Menon, Shalini, Gupton, Stephanie L.
Neural connectivity requires proper polarization of neurons, guidance to appropriate target locations, and establishment of synaptic connections. From when neurons are born to when they finally reach their synaptic partners, neurons undergo constant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::728db0832f64a5df784063a1acec3914
Autor:
Kim, Hyojin, Olsen, Reid H.J., Gupton, Stephanie L., Song, Juan, Moy, Sheryl S., Winkle, Cortney C.
During hippocampal development, newly born neurons migrate to appropriate destinations, extend axons, and ramify dendritic arbors to establish functional circuitry. These developmental stages are recapitulated in the dentate gyrus of the adult hippoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fb16ac135eb2239db1ca2ef68f7cbba
During development, neurons progress through rapid yet stereotypical shape changes to achieve proper neuronal connectivity. This morphological progression requires carefully orchestrated plasma membrane expansion, insertion of membrane components inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e3a8b737a7f26cce6319f9e56db4c37
Autor:
Gupton, Stephanie L., Gertler, Frank
Publikováno v:
PMC
Neurons establish their unique morphology by elaborating multiple neurites that subsequently form axons and dendrites. Neurite initiation entails significant surface area expansion, necessitating addition to the plasma membrane. We report that regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od________88::d962b6cc9d185c617b7b11e3de6c69a1
https://orcid.org/0000-0003-3214-4554
https://orcid.org/0000-0003-3214-4554
Autor:
Park, Charles S., McClain, Leslie M., Maglione, Christopher, Winkle, Cortney C., Gupton, Stephanie L., Valtschanoff, Juli G.
Localized plasma membrane expansion during axon branching mediated by Netrin-1 occurs via TRIM9-dependent regulation of SNARE-mediated vesicle fusion.Developmental axon branching dramatically increases synaptic capacity and neuronal surface area. Net
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::451f09f9c8372305565389912370d7d8
Filopodia are actin-based cell extensions that contribute to cell adhesion and spreading. The cytoskeleton regulators mDia2 and VASP have distinct roles in filopodia assembly and function, and VASP controls the length, dynamics, stability, and integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c20b0399d66e14c5d87e6e4f39d14eeb
Autor:
Douglas A. Lauffenburger, Shannon K. Hughes-Alford, Jenny Tadros, Richard O. Hynes, Shireen S. Rudina, Daisy N. Riquelme, Frank B. Gertler, Stephanie L. Gupton
Publikováno v:
The Journal of Cell Biology
Rockefeller UP
Rockefeller UP
Mena is an Ena/VASP family actin regulator with roles in cell migration, chemotaxis, cell–cell adhesion, tumor cell invasion, and metastasis. Although enriched in focal adhesions, Mena has no established function within these structures. We find th