Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Gennari, Luigi"'
Autor:
Falchetti Alberto, Gennari Luigi, Merlotti Daniela, Eller Vainicher Cristina, Chiodini Iacopo
Publikováno v:
Expert review of endocrinologymetabolism. 15(4)
Endogenous or exogenous (corticosteroid-induced) glucocorticoids (GCs) excess represents, together with diabetes, the most common cause of secondary osteoporosis.We present a comprehensive overview about the pathophysiology, clinical management and t
Autor:
Cronin, Owen, Subedi, Deepak, Forsyth, Laura, Goodman, Kirsteen, Lewis, Steff C., Keerie, Catriona, Walker, Allan, Porteous, Mary, Cetnarskyj, Roseanne, Ranganath, Lakshminarayan R., Selby, Peter, Hampson, Geeta, Chandra, Rama, Ho, Shu, Tobias, Jonathan H, Young-Min, Steven, McKenna, Malachi J., Crowley, Rachel K., Fraser, William D, Tang, Jonathan, Gennari, Luigi, Nuti, Rannuccio, Brandi, Maria Luisa, Del Pino-Montes, Javier, Devogelaer, Jean-Pierre, Durnez, Anne, Isaia, Giovanni Carlo, Di Stefano, Marco, Rubio, Josep Blanch, Guañabens, Núria, Seibel, Markus J., Walsh, John P, Kotowicz, Mark A., Nicholson, Geoffrey C., Duncan, Emma L, Major, Gabor, Horne, Anne, Gilchrist, Nigel L., Ralston, Stuart H.
Publikováno v:
Cronin, O, Subedi, D, Forsyth, L, Goodman, K, Lewis, S C, Keerie, C, Walker, A, Porteous, M, Cetnarskyj, R, Ranganath, L R, Selby, P, Hampson, G, Chandra, R, Ho, S, Tobias, J H, Young-Min, S, McKenna, M J, Crowley, R K, Fraser, W D, Tang, J, Gennari, L, Nuti, R, Brandi, M L, Del Pino-Montes, J, Devogelaer, J-P, Durnez, A, Isaia, G C, Di Stefano, M, Rubio, J B, Guañabens, N, Seibel, M J, Walsh, J P, Kotowicz, M A, Nicholson, G C, Duncan, E L, Major, G, Horne, A, Gilchrist, N L & Ralston, S H 2020, ' Characteristics of early Paget's disease in SQSTMI mutation carriers : baseline analysis of the ZIPP study cohort ', Journal of Bone and Mineral Research . https://doi.org/10.1002/jbmr.4007
Objectives: Mutations in SQSTM1 are strongly associated with Paget’s disease of bone (PDB) but little is known about the clinical characteristics of those with early disease. Methods: Radionuclide bone scans, biochemical markers of bone turnover an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2642::7b62c615a4223cd441a9b02f9f5c4414
https://research-information.bris.ac.uk/en/publications/8e2aa5f8-25a2-4940-a42b-b2977bdf9899
https://research-information.bris.ac.uk/en/publications/8e2aa5f8-25a2-4940-a42b-b2977bdf9899
Autor:
Ralston, Stuart, Corral-Gudino, Luis, Cooper, Cyrus, Francis, Roger M, Fraser, William D, Gennari, Luigi, Guañabens, Nuria, Javaid, M Kassim, Layfield, Robert, O'Neill, Terence W, Russell, R Graham G, Stone, Michael D, Simpson, Keith, Wilkinson, Diana, Wills, Ruth, Zillikens, M Carola, Tuck, Stephen P
Publikováno v:
Ralston, S, Corral-Gudino, L, Cooper, C, Francis, R M, Fraser, W D, Gennari, L, Guañabens, N, Javaid, M K, Layfield, R, O'Neill, T W, Russell, R G G, Stone, M D, Simpson, K, Wilkinson, D, Wills, R, Zillikens, M C & Tuck, S P 2019, ' Diagnosis and Management of Paget’s disease of Bone in Adults: A clinical guideline ', Journal of Bone and Mineral Research . https://doi.org/10.1002/jbmr.3657
An evidence-based clinical guideline for the diagnosis and management of Paget's disease of bone (PDB) was developed using GRADE methodology, by a Guideline Development Group (GDG) led by the Paget's Association (UK). A systematic review of diagnosti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a60a8116fed4efdd34abf2c17750ef07
https://ueaeprints.uea.ac.uk/id/eprint/69403/
https://ueaeprints.uea.ac.uk/id/eprint/69403/
Publikováno v:
International Journal of Endocrinology.
Osteoporosis is the most common metabolic bone disorder affecting up to 40% of postmenopausal women, characterized by a reduction in bone mass and strength leading to bone fragility and fractures. Despite the available tools for diagnosis and stratif
Autor:
Nuti, Ranuccio, Bocchia, Monica, Dotta, Francesco, Figura, Natale, Garosi, G, Gennari, Luigi, Giordano, NICOLA GIUSEPPE, Gonnelli, Stefano, Martini, Giuseppe, Pacini, Furio, Palazzuoli, A, Pondrelli, C, Rottoli, Paola, Sestini, Piersante, Valenti, R.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1820::408fd8f4a982ddec1e64856caaf460fa
http://hdl.handle.net/11365/1003917
http://hdl.handle.net/11365/1003917
Autor:
Albagha, Omar ME, Visconti, Micaela Rios, Alonso, Nerea, Wani, Sachin, Goodman, Kirsteen, Fraser, William D, Gennari, Luigi, Merlotti, Daniela, Gianfrancesco, Fernando, Esposito, Teresa, Rendina, Domenico, di Stefano, Marco, Isaia, Giancarlo, Brandi, Maria Luisa, Giusti, Francesca, Del Pino-Montes, Javier, Corral-Gudino, Luis, Gonzalez-Sarmiento, Rogelio, Ward, Lynley, Rea, Sarah L, Ratajczak, Thomas, Walsh, John P, Ralston, Stuart H
Publikováno v:
Journal of bone and mineral research (2013). doi:10.1002/jbmr.1975.
info:cnr-pdr/source/autori:Albagha OM, Visconti MR, Alonso N, Wani S, Goodman K, Fraser WD, Gennari L, Merlotti D, Gianfrancesco F, Esposito T, Rendina D, di Stefano M, Isaia G, Brandi ML, Guisti F, Del Pino-Montes J, Corral-Gudino L, Gonzalez-Sarmiento R, Ward L, Rea SL, Ratajczak T, Walsh JP, Ralston SH./titolo:Common susceptibility alleles and SQSTM1 mutations predict disease extent and severity in a multinational study of patients with Paget's disease./doi:10.1002%2Fjbmr.1975./rivista:Journal of bone and mineral research/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume
Journal of Bone and Mineral Research
info:cnr-pdr/source/autori:Albagha OM, Visconti MR, Alonso N, Wani S, Goodman K, Fraser WD, Gennari L, Merlotti D, Gianfrancesco F, Esposito T, Rendina D, di Stefano M, Isaia G, Brandi ML, Guisti F, Del Pino-Montes J, Corral-Gudino L, Gonzalez-Sarmiento R, Ward L, Rea SL, Ratajczak T, Walsh JP, Ralston SH./titolo:Common susceptibility alleles and SQSTM1 mutations predict disease extent and severity in a multinational study of patients with Paget's disease./doi:10.1002%2Fjbmr.1975./rivista:Journal of bone and mineral research/anno:2013/pagina_da:/pagina_a:/intervallo_pagine:/volume
Journal of Bone and Mineral Research
Paget's disease of bone (PDB) has a strong genetic component. Here we investigated possible associations between genetic variants that predispose to PDB and disease severity. METHODS: Allelic variants identified as predictors of PDB from genome wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::76fb9ebfebe153772fb19ef6792be614
http://hdl.handle.net/11588/699947
http://hdl.handle.net/11588/699947
Autor:
Masi, L, Becherini, L, Gennari, Luigi, Amedei, A, Colli, E, Falchetti, A, Farci, M, Silvestri, S, Gonnelli, Stefano, Brandi, Ml
Publikováno v:
Journal of Clinical Endocrinology & Metabolism. 86:2263-2269
Conversion of C(19) steroids to estrogens is catalyzed by the aromatase enzyme. Inactivating mutations of the aromatase gene are associated with decreased bone mineral density in both men and women. Genetic studies suggest that several genes contribu
Publikováno v:
International Journal of Endocrinology.
Osteocalcin is the most abundant noncollagenous protein of bone matrix. Once transcribed, this protein undergoes posttranslational modifications within osteoblastic cells before its secretion, including the carboxylation of three glutamic residues in
Publikováno v:
Journal of Osteoporosis.
Aromatase is a specific component of the cytochrome P450 enzyme system responsible for the transformation of androgen precursors into estrogens. This enzyme is encoded by the CYP19A1 gene located at chromosome 15q21.2, that is, expressed in ovary and
Autor:
Gennari, Luigi
Publikováno v:
Clinical Interventions in Aging.
Luigi Gennari, Daniela Merlotti, Ranuccio NutiDepartment of Internal Medicine, Endocrine-Metabolic Sciences and Biochemistry, University of Siena, Siena, ItalyAbstract: Selective estrogen receptor modulators (SERMs) represent a class with a growing n