Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Drouin-Ouellet, Janelle"'
Autor:
Bruzelius, Andreas, Kidnapillai, Srisaiyini, Drouin-Ouellet, Janelle, Stoker, Tom, Barker, Roger A, Rylander Ottosson, Daniella
Publikováno v:
Cells
Cells, Vol 10, Iss 3450, p 3450 (2021)
Cells, Vol 10, Iss 3450, p 3450 (2021)
Direct reprogramming is an appealing strategy to generate neurons from a somatic cell by forced expression of transcription factors. The generated neurons can be used for both cell replacement strategies and disease modelling. Using this technique, p
Autor:
Vuono, Romina, Kouli, Antonina, Legault, Emilie M, Chagnon, Lauriane, Allinson, Kieren S, La Spada, Alberto, REGISTRY Investigators Of The European Huntington's Disease Network, Biunno, Ida, Barker, Roger A, Drouin-Ouellet, Janelle
BACKGROUND: Although Huntington's disease (HD) is caused by a single dominant gene, it is clear that there are genetic modifiers that may influence the age of onset and disease progression. OBJECTIVES: We sought to investigate whether new inflammatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb08a090d1fe4b8f23acc01e57345628
https://www.repository.cam.ac.uk/handle/1810/296785
https://www.repository.cam.ac.uk/handle/1810/296785
Autor:
Birtele Marcella, Sharma Yogita, Drouin-Ouellet Janelle, Brattas Per, Shong, Lau, Rylander-Ottosson Daniella, Parmar Malin
Publikováno v:
NECTAR
Induced neurons (iNs) are somatic cells that are directly convertedto change their fate into neurons without passing through a pluripotent state. This shortensthe process of neuronal generation compared to the use ofhuman pluripotent stem cells, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::421e3c6775639e43ebc1fec30bd189d2
Publikováno v:
Intern. Society for Stem Cell Research ISSCR Conference
Parkinson’s disease (PD) is a neurodegenerative disease resulting from the progressive loss of dopaminergic cells within the nigrostriatal system. Previous work has shown that it is possible to generate dopaminergic (DA) neurons from fetal tissue a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5db18d88e10bb0e3792ca669a4fe91
Publikováno v:
Lund University
Parkinson’s disease (PD) is a neurodegenerative disease resulting from the progressive loss of dopaminergic cells within the nigrostriatal system. Previous work has shown that it is possible to generate dopaminergic (DA) neurons from fetal tissue a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::720893f1b5ebace5df0e7f05c004eacc
https://doi.org/10.5281/zenodo.2542081
https://doi.org/10.5281/zenodo.2542081
Induced neurons (iNs) are reprogrammed somatic cells that are forced to change their fate without passing through a pluripotent state, shortening the process of neuronal generation compared to the use ofhuman pluripotent stem cells.The scientific int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c1c07176deeaf99221d22994f6a4fc
Cell-based replacement therapy has great potential to address the motor symptoms of Parkinson’s disease (PD), a neurodegenerative disease resulting from the progressive loss of dopaminergic cells within the nigrostriatal system. Direct neural repro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b7192749294f4ccdd0790015e6ff5f
Autor:
Drouin-Ouellet, Janelle, Sawiak, Stephen J., Cisbani, Giulia, Kuan, Wei-Li, Saint-Pierre, Martine, Dury, Richard J., Alata, Wael, St-Amour, Isabelle, Mason, Sarah L., Lacroix, Steve, Gowland, Penny A., Francis, Susan T., Barker, Roger A., Cicchetti, Francesca
ObjectiveAlthough the underlying cause of Huntington's disease (HD) is well established, the actual pathophysiological processes involved remain to be fully elucidated. In other proteinopathies such as Alzheimer's and Parkinson's diseases, there is e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::1b394c3947e5c2e64f89645c5c61f948
Autor:
Arsenault, Dany, Drouin-Ouellet, Janelle, Saint-Pierre, Martine, Petrou, Petros, Dubois, Marilyn, Kriz, Jasna, Barker, Roger A, Cicchetti, Antonio, Cicchetti, Francesca
Deep brain stimulation (DBS) is used to treat a number of neurological conditions and is currently being tested to intervene in neuropsychiatric conditions. However, a better understanding of how it works would ensure that side effects could be minim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ecd7f8dfcef868e71a85fa0d5e9e443
https://europepmc.org/articles/PMC4457191/
https://europepmc.org/articles/PMC4457191/
Autor:
Vuono, Romina, Winder-Rhodes, Sophie, de Silva, Rohan, Cisbani, Giulia, Drouin-Ouellet, Janelle, Spillantini, Maria G., Cicchetti, Francesca, Barker, Roger A.
Huntington’s disease is a neurodegenerative disorder caused by an abnormal CAG repeat expansion within exon 1 of the huntingtin gene HTT. While several genetic modifiers, distinct from the Huntington’s disease locus itself, have been identified a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::924eb990ba333ae7391c50442be922ea
https://kar.kent.ac.uk/78973/1/awv107.pdf
https://kar.kent.ac.uk/78973/1/awv107.pdf