Zobrazeno 1 - 10
of 12
pro vyhledávání: '"David Sahner"'
Autor:
Lauren E. Chan, Elena Casiraghi, Bryan Laraway, Ben Coleman, Hannah Blau, Adnin Zaman, Nomi L. Harris, Kenneth Wilkins, Blessy Antony, Michael Gargano, Giorgio Valentini, David Sahner, Melissa Haendel, Peter N. Robinson, Carolyn Bramante, Justin Reese
Publikováno v:
medRxiv, vol 3, iss 09-09
BackgroundWith the continuing COVID-19 pandemic, identifying medications that improve COVID-19 outcomes is crucial. Studies suggest that use of metformin, an oral antihyperglycemic, is associated with reduced COVID-19 severity in individuals with dia
Autor:
Justin T. Reese, Hannah Blau, Elena Casiraghi, Timothy Bergquist, Johanna J. Loomba, Tiffany J. Callahan, Bryan Laraway, Corneliu Antonescu, Ben Coleman, Michael Gargano, Kenneth J. Wilkins, Luca Cappelletti, Tommaso Fontana, Nariman Ammar, Blessy Antony, T.M. Murali, J. Harry Caufield, Guy Karlebach, Julie A. McMurry, Andrew Williams, Richard Moffitt, Jineta Banerjee, Anthony E. Solomonides, Hannah Davis, Kristin Kostka, Giorgio Valentini, David Sahner, Christopher G. Chute, Charisse Madlock-Brown, Melissa A. Haendel, Peter N. Robinson, Heidi Spratt, Shyam Visweswaran, Joseph Eugene Flack, Yun Jae Yoo, Davera Gabriel, G. Caleb Alexander, Hemalkumar B. Mehta, Feifan Liu, Robert T. Miller, Rachel Wong, Elaine L. Hill, Lorna E. Thorpe, Jasmin Divers
Publikováno v:
EBioMedicine. 87
Stratification of patients with post-acute sequelae of SARS-CoV-2 infection (PASC, or long COVID) would allow precision clinical management strategies. However, long COVID is incompletely understood and characterised by a wide range of manifestations
Autor:
Justin T, Reese, Hannah, Blau, Timothy, Bergquist, Johanna J, Loomba, Tiffany, Callahan, Bryan, Laraway, Corneliu, Antonescu, Elena, Casiraghi, Ben, Coleman, Michael, Gargano, Kenneth J, Wilkins, Luca, Cappelletti, Tommaso, Fontana, Nariman, Ammar, Blessy, Antony, T M, Murali, Guy, Karlebach, Julie A, McMurry, Andrew, Williams, Richard, Moffitt, Jineta, Banerjee, Anthony E, Solomonides, Hannah, Davis, Kristin, Kostka, Giorgio, Valentini, David, Sahner, Christopher G, Chute, Charisse, Madlock-Brown, Melissa A, Haendel, Peter N, Robinson
Publikováno v:
medRxiv
Accurate stratification of patients with post-acute sequelae of SARS-CoV-2 infection (PASC, or long COVID) would allow precision clinical management strategies. However, the natural history of long COVID is incompletely understood and characterized b
Autor:
Thomas L. Holland, Adit A. Ginde, Roger Paredes, Thomas A. Murray, Nicole Engen, Greg Grandits, Andrew Vekstein, Noel Ivey, Ahmad Mourad, Uriel Sandkovsky, Robert L. Gottlieb, Mezgebe Berhe, Mamta K. Jain, Rubria Marines-Price, Barbine Tchamba Agbor Agbor, Lourdes Mateu, Sergio España-Cueto, Gemma Lladós, Eleftherios Mylonakis, Ralph Rogers, Fadi Shehadeh, Michael R. Filbin, Kathryn A. Hibbert, Kami Kim, Thanh Tran, Peter E. Morris, Evan P. Cassity, Barbara Trautner, Lavannya M. Pandit, Kirk U. Knowlton, Lindsay Leither, Michael A. Matthay, Angela J. Rogers, Wonder Drake, Beatrice Jones, Garyfallia Poulakou, Konstantinos N. Syrigos, Eduardo Fernández-Cruz, Marisa Di Natale, Eyad Almasri, Leire Balerdi-Sarasola, Sanjay R. Bhagani, Katherine L. Boyle, Jonathan D. Casey, Peter Chen, David J. Douin, D. Clark Files, Huldrych F. Günthard, R. Duncan Hite, Robert C. Hyzy, Akram Khan, Moses Kibirige, Robert Kidega, Ivan Kimuli, Francis Kiweewa, Jens-Ulrik Jensen, Bradley G. Leshnower, Joseph K. Lutaakome, Prasad Manian, Vidya Menon, Jose Luis Morales-Rull, D. Shane O'Mahony, J. Scott Overcash, Srikant Ramachandruni, Jay S. Steingrub, Hassan S. Taha, Michael Waters, Barnaby E. Young, Andrew N. Phillips, Daniel D. Murray, Tomas O. Jensen, Maria L. Padilla, David Sahner, Katy Shaw-Saliba, Robin L. Dewar, Marc Teitelbaum, Ven Natarajan, M. Tauseef Rehman, Sarah Pett, Fleur Hudson, Giota Touloumi, Samuel M. Brown, Wesley H. Self, Christina C. Chang, Adriana Sánchez, Amy C. Weintrob, Timothy Hatlen, Birgit Grund, Shweta Sharma, Cavan S. Reilly, Pedro Garbes, Mark T. Esser, Alison Templeton, Abdel G. Babiker, Victoria J. Davey, Annetine C. Gelijns, Elizabeth S. Higgs, Virginia Kan, Gail Matthews, B. Taylor Thompson, James D. Neaton, H. Clifford Lane, Jens D. Lundgren
Publikováno v:
ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group, Nielsen, H, Thisted, R K, Petersen, K T & Juhl, M R 2022, ' Tixagevimab–cilgavimab for treatment of patients hospitalised with COVID-19: a randomised, double-blind, phase 3 trial ', The Lancet. Respiratory Medicine, vol. 10, no. 10, pp. 972-984 . https://doi.org/10.1016/S2213-2600(22)00215-6
BACKGROUND: Tixagevimab-cilgavimab is a neutralising monoclonal antibody combination hypothesised to improve outcomes for patients hospitalised with COVID-19. We aimed to compare tixagevimab-cilgavimab versus placebo, in patients receiving remdesivir
Autor:
Thomas L. Holland, Adit A. Ginde, Roger Paredes, Thomas A. Murray, Nicole Engen, Greg Grandits, Andrew Vekstein, Noel Ivey, Ahmad Mourad, Uriel Sandkovsky, Robert L. Gottlieb, Mezgebe Berhe, Mamta Jain, Rubria Marines-Price, Barbine Tchamba Agbor Agbor, Lourdes Mateu, Sergio Espana-Cueto, Gemma Llados, Eleftherios Mylonakis, Ralph Rogers, Fadi Shehadeh, Michael R. Filbin, Kathryn A. Hibbert, Kami Kim, Thanh Tran, Peter E. Morris, Evan P. Cassity, Barbara Trautner, Lavannya M. Pandit, Kirk U. Knowlton, Lindsay Leither, Michael A. Matthay, Angela J. Rogers, Wonder Drake, Beatrice Jones, Garyfallia Poulakou, Konstantinos N. Syrigos, Eduardo Fernandez-Cruz, Marisa Di Natale, Eyad Almasri, Leire Balerdi-Sarasola, Sanjay R. Bhagani, Katherine L. Boyle, Jonathan D. Casey, Peter Chen, David J. Douin, D. Clark Files, Huldrych F. Günthard, R. Duncan Hite, Robert C. Hyzy, Akram Khan, Moses Kibirige, Robert Kidega, Ivan Kimuli, Francis Kiweewa, Jens Ulrik Stæhr Jensen, Bradley G. Leshnower, Joseph K. Lutaakome, Prasad Manian, Vidya Menon, Jose Luis Morales-Rull, Darragh O'Mahony, J. Scott Overcash, Srikant Ramachandruni, Jay S. Steingrub, Hassan S. Taha, Michael Waters, Barnaby E. Young, Andrew N. Phillips, Daniel D. Murray, Tomas O. Jensen, Maria L. Padilla, David Sahner, Katy Shaw-Saliba, Robin L. Dewar, Marc Teitelbaum, Ven Natarajan, M. Tauseef Rehman, Sarah Pett, Fleur Hudson, Giota Touloumi, Samuel M. Brown, Wesley H. Self, Christina C. Chang, Adriana Sanchez, Amy C. Weintrob, Timothy Hatlen, Birgit Grund, Shweta Sharma, Cavan S. Reilly, Pedro Garbes, Mark T. Esser, Alison Templeton, Abdel G. Babiker, Victoria J. Davey, Annetine C. Gelijns, Elizabeth S. Higgs, Virginia Kan, Gail Matthews, B. Taylor Thompson, James D. Neaton, H. Clifford Lane, Jens Lundgren
Publikováno v:
SSRN Electronic Journal.
Autor:
David Sahner, Richard J. Williams
An approach is described to building a clinical decision support tool which leverages a partially instantiated graphical model optimized through quantum annealing. Potential advantages of such a strategy include the practical, and potentially real-ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9701f0a379d8c99bee68f92784baf7
https://doi.org/10.1101/2020.12.13.20248138
https://doi.org/10.1101/2020.12.13.20248138
Autor:
Chris Allen, Jack M. Anthony, Norman W. Baylor, John F. Beeler, Dave Boclair, Arthur A. Boni, Craig C. Bradley, Lowell W. Busenitz, Mark Byrne, Robert J. Calcaterra, John Conner, Gerry J. Elman, Steven M. Ferguson, François Ferré, Toby Freedman, Susan Garfield, The Honorable James C. Greenwood, Neal Gutterson, Philip Haworth, Gail H. Javitt, Uma S. Kaundinya, Donald R. Kirsch, Konstantin S. Kostov, Joan E. Kureczka, Lynn Johnson Langer, Maria Lopez, Lara V. Marks, Magda Marquet, Gayle M. Mills, Bill Minshall, Jay Peterson, Rabi Prusti, David Sahner, Stephen M. Sammut, Alaap B. Shah, Craig Shimasaki, David C. Spellmeyer, Henri A. Termeer, Donna-Bea Tillman, Gergana Todorova, Tom D. Walker, Robert E. Wanerman, Laurie R. Weingart, Gladys B. White, Don Wuchterl, Jay Z. Zhang, Jimmy Zhimin Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71a4774dc3404dcea99a9aa0c4fa62bc
https://doi.org/10.1016/b978-0-12-815585-1.00053-x
https://doi.org/10.1016/b978-0-12-815585-1.00053-x
Autor:
David Sahner, David C. Spellmeyer
Artificial intelligence (AI), specifically machine learning (ML) models that make biological or clinical predictions, may indeed be transformative within the realms of drug and biologic discovery and development. ML has already made inroads within th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55622a5f67928fc7a52a03efa247d631
https://doi.org/10.1016/b978-0-12-815585-1.00028-0
https://doi.org/10.1016/b978-0-12-815585-1.00028-0
Autor:
David Sahner
Publikováno v:
Wallace Stevens Journal. 37:49-69
Autor:
J Michael, Kilby, R Pat, Bucy, Donna, Mildvan, Margaret, Fischl, Jorge, Santana-Bagur, Jeff, Lennox, Chris, Pilcher, Andrew, Zolopa, Jody, Lawrence, Richard B, Pollard, Raphaelle El, Habib, David, Sahner, Lawrence, Fox, Evgenia, Aga, Ronald J, Bosch, Ronald, Mitsuyasu
Publikováno v:
The Journal of Infectious Diseases. 194:1672-1676
Strategies to limit life-long dependence on antiretroviral therapy (ART) are needed. We randomized 81 human immunodeficiency virus (HIV)-infected subjects to 4 interventional arms involving continued ART plus ALVAC vCP1452 (or placebo) with or withou