Zobrazeno 1 - 10
of 41
pro vyhledávání: '"David Dilworth"'
Autor:
Ronan P. Hanley, David Y. Nie, John R. Tabor, Fengling Li, Amin Sobh, Chenxi Xu, Natalie K. Barker, David Dilworth, Taraneh Hajian, Elisa Gibson, Magdalena M. Szewczyk, Peter J. Brown, Dalia Barsyte-Lovejoy, Laura E. Herring, Gang Greg Wang, Jonathan D. Licht, Masoud Vedadi, Cheryl H. Arrowsmith, Lindsey I. James
Publikováno v:
Journal of the American Chemical Society. 145:8176-8188
Autor:
David Dilworth, Matthew J. Blow, Ji E. Lee, Asaf Salamov, Hyunsoo Na, Ronan C. O'Malley, Yuko Yoshinaga, Chris Daum, Matthew Mingay, Yu Zhang, Leo A Baumgart
Publikováno v:
Nature Methods. 18:1499-1505
Organisms orchestrate cellular functions through transcription factor (TF) interactions with their target genes, although these regulatory relationships are largely unknown in most species. Here we report a high-throughput approach for characterizing
Autor:
Marcus A. Cheek, Aiping Dong, Renato Ferreira de Freitas, Dalia Barsyte-Lovejoy, Aliakbar Khalili Yazdi, Jinrong Min, Fengling Li, Victoria Vu, Albina Bolotokova, Lindsey I. James, Jack Greenblatt, Naimee Mehta, Irina K. Popova, David Dilworth, Ming Lei, Raquel Arminda Carvalho Machado, Ronan P Hanley, David Y Nie, Matthieu Schapira, Mengqi Zhou, Elisa Gibson, Cheryl H. Arrowsmith, Michael-Christopher Keogh, Suzanne Ackloo, Matthew R. Marunde, Mona Alqazzaz, Dmitri Kireev, Nathan W. Hall, Peter Brown, Abdellah Allali-Hassani, Sina Kazemzadeh, Edyta Marcon, Tigran M. Abramyan, Dominic D G Owens, Yanli Liu, Magdalena M. Szewczyk, Matthew J. Meiners, Irene Chau, Su Qin, Masoud Vedadi
Publikováno v:
Nat Chem Biol
Nuclear receptor-binding SET domain-containing 2 (NSD2) is the primary enzyme responsible for the dimethylation of lysine 36 of histone 3 (H3K36), a mark associated with active gene transcription and intergenic DNA methylation. In addition to a methy
Autor:
Christopher Daum, Kurt LaButti, Andrea Kuftin, Sara Calhoun, Shawn R. Starkenburg, Yuliya A. Kunde, Igor V. Grigoriev, Tisza Ann Szeremy Bell, Sirma Mihaltcheva, Lukas R. Dahlin, Katherine B. Louie, Benjamin P. Bowen, Michael T. Guarnieri, Trent R. Northen, David Dilworth, Daniel Treen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, vol 4, iss 1
Communications Biology
Communications biology, vol 4, iss 1
Communications Biology
Microalgae efficiently convert sunlight into lipids and carbohydrates, offering bio-based alternatives for energy and chemical production. Improving algal productivity and robustness against abiotic stress requires a systems level characterization en
Autor:
Magdalena M. Szewczyk, Genna M. Luciani, Victoria Vu, Alex Murison, David Dilworth, Mathieu Lupien, Cheryl H Arrowsmith, Mark D. Minden, Dalia Barsyte-Lovejoy
Protein methyltransferase 5 (PRMT5) symmetrically dimethylates arginine residues leading to regulation of transcription and splicing programs. Although PRMT5 has emerged as an attractive oncology target, the molecular determinants of PRMT5 dependency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92cd3c07483545e7e1c3e45adaa158e
https://doi.org/10.1101/2022.02.02.478789
https://doi.org/10.1101/2022.02.02.478789
Autor:
Magdalena M. Szewczyk, Genna M. Luciani, Victoria Vu, Alex Murison, David Dilworth, Samir H. Barghout, Mathieu Lupien, Cheryl H. Arrowsmith, Mark D. Minden, Dalia Barsyte-Lovejoy
Publikováno v:
Redox Biol
Protein methyltransferase 5 (PRMT5) symmetrically dimethylates arginine residues leading to regulation of transcription and splicing programs. Although PRMT5 has emerged as an attractive oncology target, the molecular determinants of PRMT5 dependency
Publikováno v:
Biochemistry and Cell Biology. 98:42-49
FK506-binding proteins (FKBPs) alter the conformation of proteins via cis–trans isomerization of prolyl-peptide bonds. While this activity can be demonstrated in vitro, the intractability of detecting prolyl isomerization events in cells has limite
Autor:
David Dilworth
Publikováno v:
Overheard in Seville: Bulletin of the Santayana Society. 38:53-65
Autor:
Laia Carreté, Jan Breuer, Minou Nowrousian, Laura Sandor, Ramona Lütkenhaus, Kerrie Barry, David Dilworth, Jasmyn Pangilinan, Stefanie Pöggeler, Igor V. Grigoriev, Anna Lipzen, Toni Gabaldón, Stefanie Traeger, Alan Kuo
Publikováno v:
Genetics
Many filamentous ascomycetes develop three-dimensional fruiting bodies for production and dispersal of sexual spores. Fruiting bodies are among the most complex structures differentiated by ascomycetes; however, the molecular mechanisms underlying th
Autor:
Neda Savic, Joseph M Dobbs, Misha Bilenky, David Dilworth, Christopher J. Nelson, Martin Hirst, Shawn P. Shortill
Publikováno v:
Genetics
Gene duplications increase organismal robustness by providing freedom for gene divergence or by increasing gene dosage. The yeast histone chaperones Fpr3 and Fpr4 are paralogs that can assemble nucleosomes in vitro; however, the genomic locations the