Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Christine Hui Shan Chan"'
Publikováno v:
Biomedicines
Volume 11
Issue 2
Pages: 486
Volume 11
Issue 2
Pages: 486
Synaptic dysfunction may underlie the pathophysiology of Parkinson’s disease (PD), a presently incurable condition characterized by motor and cognitive symptoms. Here, we used quantitative proteomics to study the role of PHD Finger Protein 8 (PHF8)
Autor:
Nicodemus E. Oey, Puneet Opal, Louis C.S. Tan, Francisco Cardoso, KRay R. Chaudhuri, Carlo Colosimo, Yun Cheng Wu, Pramod Kumar Pal, Beomseok Jeon, Shen-Yang Lim, Daniel Truong, Werner Poewe, Eng-King Tan, Alberto Albanese, H.A. Jinnah, Christine Hui Shan Chan
Publikováno v:
Parkinsonism & Related Disorders
Highlights • COVID-19 has significant impact on PD research and education activities. • Country-specific restrictions may pose challenges to PD research and require careful adaptations. • Neurological Symptoms of COVID-19 may overlap with PD.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd18fd96fcd52be3f375720b9df320a5
http://hdl.handle.net/10807/172685
http://hdl.handle.net/10807/172685
Publikováno v:
Brain, Behavior, and Immunity
Autor:
Christine Hui Shan Chan, Eng-King Tan
Publikováno v:
Archives of Medical Research
The COVID-19 pandemic has kicked off a global race to launch clinical trials of experimental vaccines and treatments for the coronavirus. Worldwide, as resources are directed toward accelerating the research into unravelling the mechanism of COVID-19
Autor:
Alberto Albanese, H.A. Jinnah, Puneet Opal, Daniel Truong, Yun Cheng Wu, Werner Poewe, Francisco Cardoso, Carlo Colosimo, Christine Hui Shan Chan, K. Ray Chaudhuri, Shen-Yang Lim, Beomseok Jeon, Eng-King Tan, Louis C. Tan, Pramod Kumar Pal
Publikováno v:
Journal of the Neurological Sciences
Publikováno v:
Cell Adhesion & Migration. 5:463-471
Recent findings suggest that Ring finger protein 146 (RNF146), also called Iduna, have neuroprotective property due to its inhibition of Parthanatos via binding with Poly(ADP-ribose) (PAR). The Parthanatos is a PAR dependent cell death that has been
Autor:
Patrick Ho, Tit Meng Lim, Zhi Dong Zhou, Shin Hui Ng, Christine Hui Shan Chan, Xiao-Dong Zhang, Shao Ping Xie, Fathima Shaffra Refai, Eng-King Tan
Publikováno v:
Free radical biologymedicine. 68
PINK1 mutations cause autosomal recessive forms of Parkinson disease (PD). Previous studies suggest that the neuroprotective function of wild-type (WT) PINK1 is related to mitochondrial homeostasis. PINK1 can also localize to the cytosol; however, th
Autor:
Eng-King Tan, Xiao-hong Xu, Zhi-Cheng Xiao, Christine Hui Shan Chan, Zhi Dong Zhou, Quan-Hong Ma
Publikováno v:
Cell adhesionmigration. 5(4)
The amyloid-beta (Aβ) peptide is the derivative of amyloid precursor protein (APP) generated through sequential proteolytic processing by β- and γ-secretases. Excessive accumulation of Aβ, the main constituent of amyloid plaques, has been implica