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pro vyhledávání: '"Benjamin S. Roberts"'
Publikováno v:
Frontiers in Cell and Developmental Biology. 10
The secretory pathway is an intracellular highway for the vesicular transport of newly synthesized proteins that spans the endoplasmic reticulum (ER), Golgi, lysosomes and the cell surface. A variety of cargo receptors, chaperones, and quality contro
Publikováno v:
J Cell Sci
Lipoprotein lipase (LPL) is a secreted triglyceride lipase involved in the clearance of very-low-density lipoproteins and chylomicrons from circulation. LPL is expressed primarily in adipose and muscle tissues and transported to the capillary lumen.
Autor:
Ellis M. Pearson, Ming Jing Wu, Aspen R. Gutgsell, Alan T. Remaley, Anna Wolska, Saskia B. Neher, Benjamin S. Roberts
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2456-2465 (2018)
LPL is a secreted enzyme that hydrolyzes triglycerides from circulating lipoproteins. Individuals lacking LPL suffer from severe hypertriglyceridemia, a risk factor for acute pancreatitis. One potential treatment is to administer recombinant LPL as a
Autor:
Mario J. Borgnia, Edward H. Egelman, Fengbin Wang, Benjamin S. Roberts, Saskia B. Neher, Joshua D. Strauss, Kathryn H. Gunn
Publikováno v:
Proc Natl Acad Sci U S A
Lipases are enzymes necessary for the proper distribution and utilization of lipids in the human body. Lipoprotein lipase (LPL) is active in capillaries, where it plays a crucial role in preventing dyslipidemia by hydrolyzing triglycerides from packa
Publikováno v:
Mol Cell Endocrinol
Lipids play a critical role in energy metabolism, and a suite of proteins is required to deliver lipids to tissues. Several of these proteins require an intricate endoplasmic reticulum (ER) quality control (QC) system and unique secondary chaperones
Autor:
Benjamin S. Roberts, Ming Jing Wu, Saskia B. Neher, Melissa A. Babilonia-Rosa, Lindsey J. Broadwell
Lipoprotein lipase (LPL) is a secreted lipase that clears triglycerides from the blood. Proper LPL folding and exit from the endoplasmic reticulum (ER) require lipase maturation factor 1 (LMF1), an ER‐resident transmembrane protein, but the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e5dc5a3f4fe1a1fa39a94bd0906e2e
https://europepmc.org/articles/PMC6166125/
https://europepmc.org/articles/PMC6166125/
Publikováno v:
Medicine & Science in Sports & Exercise. 35:519-524
ROBERTS, B. S., K. S. KAMEL, C. E. HEDRICK, S. P. MCLEAN, and R. L. SHARP. Effect of a FastSkin TM Suit on Submaximal Freestyle Swimming. Med. Sci. Sports Exerc., Vol. 35, No. 3, pp. 519 –524, 2003. Purpose: Nine male collegiate swimmers swam three