Zobrazeno 1 - 10
of 717
pro vyhledávání: '"Aviv Regev"'
Autor:
Davide Placido, Bo Yuan, Jessica X. Hjaltelin, Chunlei Zheng, Amalie D. Haue, Piotr J. Chmura, Chen Yuan, Jihye Kim, Renato Umeton, Gregory Antell, Alexander Chowdhury, Alexandra Franz, Lauren Brais, Elizabeth Andrews, Debora S. Marks, Aviv Regev, Siamack Ayandeh, Mary T. Brophy, Nhan V. Do, Peter Kraft, Brian M. Wolpin, Michael H. Rosenthal, Nathanael R. Fillmore, Søren Brunak, Chris Sander
Publikováno v:
Placido, D, Yuan, B, Hjaltelin, J X, Zheng, C, Haue, A D, Chmura, P J, Yuan, C, Kim, J, Umeton, R, Antell, G, Chowdhury, A, Franz, A, Brais, L, Andrews, E, Marks, D S, Regev, A, Ayandeh, S, Brophy, M T, Do, N V, Kraft, P, Wolpin, B M, Rosenthal, M H, Fillmore, N R, Brunak, S & Sander, C 2023, ' A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories ', Nature Medicine, vol. 29, pp. 1113-1122 . https://doi.org/10.1038/s41591-023-02332-5
Pancreatic cancer is an aggressive disease that typically presents late with poor outcomes, indicating a pronounced need for early detection. In this study, we applied artificial intelligence methods to clinical data from 6 million patients (24,000 p
Autor:
Methodios Ximerakis, Kristina M. Holton, Richard M. Giadone, Ceren Ozek, Monika Saxena, Samara Santiago, Xian Adiconis, Danielle Dionne, Lan Nguyen, Kavya M. Shah, Jill M. Goldstein, Caterina Gasperini, Ioannis A. Gampierakis, Scott L. Lipnick, Sean K. Simmons, Sean M. Buchanan, Amy J. Wagers, Aviv Regev, Joshua Z. Levin, Lee L. Rubin
Publikováno v:
Nature Aging. 3:327-345
Aging is a complex process involving transcriptomic changes associated with deterioration across multiple tissues and organs, including the brain. Recent studies using heterochronic parabiosis have shown that various aspects of aging-associated decli
Autor:
Karthik A. Jagadeesh, Kushal K. Dey, Daniel T. Montoro, Rahul Mohan, Steven Gazal, Jesse M. Engreitz, Ramnik J. Xavier, Alkes L. Price, Aviv Regev
Publikováno v:
Nature Genetics. 54:1479-1492
Publikováno v:
bioRxiv
During embryonic development, pluripotent cells assume specialized identities by adopting particular gene expression profiles. However, systematically dissecting the underlying regulation of mRNA transcription and degradation remains a challenge, esp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c443b0d649818cb4aecf9c54adad592
https://doi.org/10.1101/2023.04.20.537620
https://doi.org/10.1101/2023.04.20.537620
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
Supplementary Figures related to Figures 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc3d2abf491d2aed509bace98e32b78
https://doi.org/10.1158/2159-8290.22541081.v1
https://doi.org/10.1158/2159-8290.22541081.v1
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
Processed data for bulk RNA-seq of primary tumors isolated from KP, KPS-HET and KPS animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b34017cdb6d509327a6779c56532668
https://doi.org/10.1158/2159-8290.22541084
https://doi.org/10.1158/2159-8290.22541084
Autor:
Marios Giannakis, Jonathan A. Nowak, Aviv Regev, Shuji Ogino, Steven M. Corsello, Eliezer M. Van Allen, Kimmie Ng, Scott Rodig, Orit Rozenblatt-Rosen, Michael H. Rosenthal, Asaf Rotem, Lauren K. Brais, Evisa Gjini, Kristen Felt, Mei-Ju Su, Isaac Wakiro, Saud H. AlDubayan, Matan Hofree, David Liu, Carino Gurjao
Immunotherapy with checkpoint inhibitors, such as the programmed death-1 (PD-1) antibodies pembrolizumab and nivolumab, are effective in a variety of tumors, yet not all patients respond. Tumor microsatellite instability-high (MSI-H) has emerged as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442c07827498333d7be19a173758bafe
https://doi.org/10.1158/2326-6066.c.6549951
https://doi.org/10.1158/2326-6066.c.6549951
Autor:
Marios Giannakis, Jonathan A. Nowak, Aviv Regev, Shuji Ogino, Steven M. Corsello, Eliezer M. Van Allen, Kimmie Ng, Scott Rodig, Orit Rozenblatt-Rosen, Michael H. Rosenthal, Asaf Rotem, Lauren K. Brais, Evisa Gjini, Kristen Felt, Mei-Ju Su, Isaac Wakiro, Saud H. AlDubayan, Matan Hofree, David Liu, Carino Gurjao
Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2295fe73df274f5e33f389d9ed062002
https://doi.org/10.1158/2326-6066.22542492.v1
https://doi.org/10.1158/2326-6066.22542492.v1
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
Processed data for bulk ATAC-seq of isogenic SMARCA4-WT and -KO cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74e81c89c1f111fdc821cff53ec855d
https://doi.org/10.1158/2159-8290.22541096.v1
https://doi.org/10.1158/2159-8290.22541096.v1
Autor:
Tyler Jacks, Jason D. Buenrostro, Aviv Regev, Carla F. Kim, Charles M. Rudin, Natasha Rekhtman, Gregory J. Riely, Roderick T. Bronson, Manav Gupta, Kevin Meli, Francisco J. Sánchez-Rivera, Peter M.K. Westcott, Vinay K. Kartha, Manon Miller, Adam J. Schoenfeld, Isabella Del Priore, Jonathan Y. Kim, Lydia P. DeAngelo, Manyuan Liu, Arjun Bhutkar, Lindsay M. LaFave, Sai Ma, Carla P. Concepcion
Mutations and copy number alterations in PDX models used in this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2727f2c645d5056a98ef4b1e7ac249c5
https://doi.org/10.1158/2159-8290.22541078
https://doi.org/10.1158/2159-8290.22541078