Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dejana, Elisabetta"'
Autor:
Krispin, Shlomo, Stratman, Amber N., Melick, Chase H., Stan, Radu V., Malinverno, Matteo, Gleklen, Jamie, Castranova, Daniel, Dejana, Elisabetta, Weinstein, Brant M.
The assembly of a functional vascular system requires a coordinated and dynamic transition from activation to maturation. High vascular endothelial growth factor activity promotes activation, including junction destabilization and cell motility. Matu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7263a5e8e44e62c8b75ff81dc0bdf1dd
https://europepmc.org/articles/PMC5785447/
https://europepmc.org/articles/PMC5785447/
Autor:
Gordon, Emma J, Fukuhara, Daisuke, Weström, Simone, Padhan, Narendra, Sjöström, Elisabet O, van Meeteren, Laurens, He, Liqun, Orsenigo, Fabrizio, Dejana, Elisabetta, Bentley, Katie, Spurkland, Anne, Claesson-Welsh, Lena, Sub Cell Biology, Celbiologie
Publikováno v:
Science Signaling [E], 9(437). American Association for the Advancement of Science
Activation of vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) by VEGF binding is critical for vascular morphogenesis. In addition, VEGF disrupts the endothelial barrier by triggering the phosphorylation and turnover of the junctional mo
Autor:
Li, Xiujuan, Padhan, Narendra, Sjöström, Elisabet O, Roche, Francis P, Testini, Chiara, Honkura, Naoki, Sáinz-Jaspeado, Miguel, Gordon, Emma, Bentley, Katie, Philippides, Andrew, Tolmachev, Vladimir, Dejana, Elisabetta, Stan, Radu V, Vestweber, Dietmar, Ballmer-Hofer, Kurt, Betsholtz, Christer, Pietras, Kristian, Jansson, Leif, Claesson-Welsh, Lena
Publikováno v:
Nature communications
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
The specific role of VEGFA-induced permeability and vascular leakage in physiology and pathology has remained unclear. Here we show that VEGFA-induced vascular leakage depends on signalling initiated via the VEGFR2 phosphosite Y949, regulating dynami
Autor:
Annamari Alitalo, Denis Tvorogov, Pipsa Saharinen, Kari Alitalo, Young Jun Koh, Andrey Anisimov, Petra Korpisalo, Seppo Ylä-Herttuala, Fabrizio Orsenigo, Gou Young Koh, Michael Jeltsch, Chulhee Choi, Eun Chun Han, Yuri An, Veli-Matti Leppänen, Salla Keskitalo, Tanja Holopainen, Tuomas Tammela, Elisabetta Dejana, Emilia I. Gaal
Publikováno v:
Circulation
Background— There is an unmet need for proangiogenic therapeutic molecules for the treatment of tissue ischemia in cardiovascular diseases. However, major inducers of angiogenesis such as vascular endothelial growth factor (VEGF/VEGF-A) have side e