Zobrazeno 1 - 10
of 34
pro vyhledávání: '"ZHAO Rong"'
Publikováno v:
Frontiers in Microbiology
Pleomorphic Trypanosoma brucei are best known for their tightly controlled cell growth and developmental program, which ensures their transmissibility and host fitness between the mammalian host and insect vector. However, after long-term adaptation
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-12 (2020)
Parasites & Vectors
Parasites & Vectors
BackgroundVacuolar H+-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles. Beyond its role in pH maintenance, the involvement of V-ATPase in endocytosis is well documented in mam
Autor:
Liping Duan, Weisi Wang, Shi-Zhu Li, De-Hua Lai, Junmin Yao, Yingfang Yu, Geoff Hide, Xiao-Li Cai, Zhao-Rong Lun, Hongjin Bai, Xuan Zhang
Animal trypanosomiasis, caused by the members of subgenus Trypanozoon (Trypanosoma brucei brucei, T. evansi and T. equiperdum), has reduced animal productivity leading to significant negative economic impacts in endemic regions. Due to limited drug d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b013a67f7727f3a02b031a29273dd0b4
Publikováno v:
Mol Microbiol
The flagellated eukaryote Trypanosoma brucei alternates between the insect vector and the mammalian host and proliferates through an unusual mode of cell division. Cell division requires flagellum motility-generated forces, but flagellum motility exe
Autor:
George W. Lubega, Yan Dai, Barbara Nerima, Monica Namayanja, Zhao-Rong Lun, Enock Matovu, Chen Zhengjun
Publikováno v:
Experimental Parasitology. 174:31-41
Trypanosoma brucei are extracellular hemoflagellate protozoan parasites and one of the causative agents of a devastating zoonotic disease called African Trypanosomiasis. In humans, the disease is caused by Trypanosoma brucei rhodensiense and Trypanos
Publikováno v:
RNA. 23:333-345
The multisubunit eukaryotic initiation factor 3 (eIF3) plays multiple roles in translation but is poorly understood in trypanosomes. The putative subunits eIF3a and eIF3f of Trypanosoma brucei (TbIF3a and TbIF3f) were overexpressed and purified, and
Publikováno v:
mSphere, Vol 4, Iss 3 (2019)
mSphere, Vol 4, Iss 3, p e00199-19 (2019)
mSphere, Vol 4, Iss 3, p e00199-19 (2019)
The early divergent protozoan parasite Trypanosoma brucei alternates between the insect vector and the mammalian hosts during its life cycle and proliferates through binary cell fission. The cell cycle control system in T. brucei differs substantiall
Publikováno v:
Cell cycle (Georgetown, Tex.). 18(5)
Trypanosoma (Herpetosoma) lewisi is a globally distributed rat trypanosome, currently considered as a zoonotic pathogen; however, a detailed understanding of the morphological events occurring during the cell cycle is lacking. This study aimed to inv
Autor:
George W. Lubega, Enock Matovu, Zhi-Shen Xu, Claire M. Mugasa, Zhao-Rong Lun, Monica Namyanja, Zhengjun Chen
Publikováno v:
AAS Open Research. 2:165
Background: Trypanosoma brucei, a causative agent of African Trypanosomiasis, is known to cross the blood brain barrier during the second stage of the disease. It was previously suggested that this parasite crosses the blood brain barrier in a manner
Publikováno v:
Autophagy. 13(4)
Autophagy is a catabolic cellular process required to maintain protein synthesis, energy production and other essential activities in starved cells. While the exact nutrient sensor(s) is yet to be identified, deprivation of amino acids, glucose, grow