Zobrazeno 1 - 10
of 22
pro vyhledávání: '"339"'
Autor:
Dhalla, A. M., Li, B., Alibhai, M. F., Yost, K. J., Hemmingsen, J. M., Atkins, W. M., Schineller, J., Villafranca, J. J.
In order to understand the nature of ATP and L-glutamate binding to glutamine synthetase, and the involvement of Arg 339 and Arg 359 in catalysis, these amino acids were changed to cysteine via site-directed mutagenesis. Individual mutations (Arg-->C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d07384ac3485e3507070b374e0059a14
https://europepmc.org/articles/PMC2142696/
https://europepmc.org/articles/PMC2142696/
Previous reports by us and others demonstrated that G protein-coupled receptors interact functionally with Rab GTPases. Here, we show that the β(2)-adrenergic receptor (β(2)AR) interacts with the Rab geranylgeranyltransferase α-subunit (RGGTA). Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc41697bfc6160519891ad66cd980d0
https://europepmc.org/articles/PMC4205129/
https://europepmc.org/articles/PMC4205129/
Publikováno v:
Biochemistry. 59:351-363
Aryl acids are most commonly found in iron-scavenging siderophores but are not limited to them. The nonribosomal peptide synthetase (NRPS) codes of aryl acids remain poorly elucidated relative to those of amino acids. Here, we defined more precisely
Publikováno v:
The Journal of biological chemistry. 266(12)
We have identified, in nuclear extracts of NIH-3T3 fibroblasts, a factor which binds a sequence between -339 and -361 in the mouse alpha 1(I) collagen promoter. A 3-base pair substitution mutation introduced in this promoter element, which abolishes
Autor:
Fei Wang, Min Jiang, Xianfeng Ye, Jie Zhou, Yan Huang, Weiliang Dong, Fei Huang, Zhongli Cui, Ying Hou, Zhoukun Li, Jiangfeng Ma, Yicheng Wang
6-Chloro-2-benzoxazolinone (CDHB) is a precursor of herbicide, insecticide, and fungicide synthesis and has a broad spectrum of biological activity. Pigmentiphaga sp. strain DL-8 can transform CDHB into 2-amino-5-chlorophenol (2A5CP), which it then u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abad1ee06a3b07d69f0896fec598567
https://europepmc.org/articles/PMC5335537/
https://europepmc.org/articles/PMC5335537/
Autor:
Jeffrey T. Bolin, Michel Sylvestre, Sonali Dhindwal, David B. Neau, Pravindra Kumar, Thi Thanh My Pham, Lindsay D. Eltis, Leticia Gómez-Gil
Publikováno v:
Journal of Bacteriology
Journal of Bacteriology, American Society for Microbiology, 2016, 198 (10), pp.1499-512. ⟨10.1128/jb.00952-15⟩
Journal of Bacteriology, American Society for Microbiology, 2016, 198 (10), pp.1499-512. ⟨10.1128/jb.00952-15⟩
Biphenyl dioxygenase, the first enzyme of the biphenyl catabolic pathway, is a major determinant of which polychlorinated biphenyl (PCB) congeners are metabolized by a given bacterial strain. Ongoing efforts aim to engineer BphAE, the oxygenase compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e491d31061aa41d73aa2c9680d8280
https://hal-riip.archives-ouvertes.fr/pasteur-01351090
https://hal-riip.archives-ouvertes.fr/pasteur-01351090
Publikováno v:
Biochemical and Biophysical Research Communications. 244:172-177
Serine proteinase inhibitors function as regulators of serine proteinase activity in a variety of physiological processes. Proteinase inhibitor 8 (PI8) is a 45 kDa member of the ovalbumin family of serpins that is an inhibitor of trypsin-like protein
Autor:
Schober Pa, Patricia A. Jennings, Haggett Kd, Lloyd D. Graham, Robert George Whittaker, Le Brocque Ds
Publikováno v:
Biochemistry. 32:6250-6258
In the past, several point mutations have been introduced individually into the substrate-binding site of alpha-lytic protease (EC 3.4.21.12) and shown to affect its specificity in a predictable manner [Bone, R., Silen, J. L., & Agard, D. A. (1989) N
Publikováno v:
Chirality.
Stereoselective metabolism of propranolol side-chain glucuronidation was studied for two recombinant human uridine diphosphate glucuronosyltransferases (UGTs), UGT1A9 and UGT2B7. The S- and R-propranolol side-chain glucuronides produced in the incuba
Publikováno v:
Journal of molecular biology. 368(1)
The catalytic pentad of tyrosine recombinases, that assists the tyrosine nucleophile, includes a conserved histidine/tryptophan (His/Trp-III). Flp and Cre harbor tryptophan at this position; most of their kin recombinases display histidine. Contrary