Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hyun Soo Park"'
Autor:
Byung Seok Moon, Anhye Kim, Howard Lee, Min Hee Son, Su Bin Kim, Bom Sahn Kim, Jun Hee Jang, Hyun Soo Park, Heechan Lee, Seol Ju Moon, Sun Mi Park, Sang Keun Woo, Jee Hyun Kim, Sang Eun Kim, Jung Sunwoo, In Hyun Lee
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1747-1755 (2021)
Clinical and Translational Science
Clinical and Translational Science
DHP107 is a newly developed lipid‐based oral formulation of paclitaxel. We evaluated the in vivo tissue pharmacokinetics (PKs) of DHP107 in mice and patients using positron emission tomography (PET). Radioisotope‐labeled [3H]DHP107 and [18F]DHP10
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 378:10-19
The secretion of platelet-derived growth factors (PDGFs) into vascular smooth muscle cells (VSMCs) induced by specific stimuli, such as oxidized low-density lipoprotein (LDL) cholesterol, initially increases the proliferation and migration of VSMCs,
Autor:
Hyun-Soo Park, Miji Lee, Keun-Woo Jang, Kyung-Sun Heo, Jeong Won Park, Joo-Hui Han, Chang-Seon Myung, Do-Hyung Lee
Publikováno v:
Acta Pharmacol Sin
Propionate is a short-chain fatty acid (SCFA) mainly produced from carbohydrates by gut microbiota. Sodium propionate (SP) has shown to suppress the invasion in G protein-coupled receptor 41 (GPR41) and GPR43-overexpressing breast cancer cells. In th
Publikováno v:
Experimental Neurobiology
Synaptic dopamine (DA) is mainly regulated by the presynaptic DA transporter (DAT). Single-photon emission computerized tomography (SPECT) with the DAT radiotracer [123I]FP-CIT assesses changes in synaptic DA availability when endogenous DA displaces
TSPO Expression Modulatory Effect of Acetylcholinesterase Inhibitor in the Ischemic Stroke Rat Model
Autor:
Byung Seok Moon, In Ho Song, Yoo Sung Song, Jae Ho Jung, Sanghee Lee, Hyun Soo Park, Byung Chul Lee, Sang Eun Kim
Publikováno v:
Cells
Cells, Vol 10, Iss 1350, p 1350 (2021)
Volume 10
Issue 6
Cells, Vol 10, Iss 1350, p 1350 (2021)
Volume 10
Issue 6
We performed in vivo PET imaging with 3-[18F]F-CP118,954 (1) for acetylcholinesterase (AChE) and [18F]fluoromethyl-PBR28-d2 (2) for translocator protein 18-kDa (TSPO) to investigate the inflammatory brain response after stroke. Imaging studies were p
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 33:396-402
Background: Integrin αvβ3 is a molecular marker for the estimation of tumor angiogenesis. 99mTc-IDA-D-[c(RGDfK)]2 (also known as BIK-505) is a recently developed radiotracer for single-pho...
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 32:288-296
Integrin αvβ3 is a molecular marker for the estimation of tumor angiogenesis and is an imaging target for radiolabeled Arg-Gly-Asp (RGD) peptides. In this study, the authors investigated the clinical efficacy and safety of a novel radiolabeled RGD
Autor:
Sang-Hyuk Jung, Tae‐Wan Lim, Kyung-Sun Heo, Do-Hyung Lee, Khong Trong Quan, Hyun-Soo Park, Eunji Jo, MinKyun Na, Chang-Seon Myung, Joo-Hui Han
Publikováno v:
British Journal of Pharmacology. 174:4140-4154
BACKGROUND AND PURPOSE The proliferation and migration of vascular smooth muscle cells (VSMCs) induced by platelet-derived growth factor (PDGF) are important steps in cardiovascular diseases, including neointimal lesion formation, myocardial infarcti
Autor:
Hyun-Soo Park, Sang-Hyuk Jung, Do-Hyung Lee, Eun-Ji Ga, Chang-Seon Myung, Joo-Hui Han, Eun Ji Jo, Kyung-Sun Heo
Publikováno v:
Journal of Pharmaceutical Investigation. 47:365-371
Hypertension is a major risk factor for cardiovascular diseases and is known to contribute to complications, such as atherosclerosis and diabetes. The aim of this study was to investigate the possible synergistic effects of candesartan, an angiotensi
Autor:
Sangeun Lee, Min Jung Lee, Jun-Hwan Moon, Gi Seon Park, Young Nang Kim, Byung Seok Moon, Yoo Mi Shin, Hyun Soo Park, Hyung Keun Lee, Byung Chul Lee
Publikováno v:
Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:Antimuscarinic agents are widely used as the first line therapy for overactive bladder (OAB). However, concerns have emerged about side effects of antimuscarinics in cen...