Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Chung-Ying Tsai"'
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-15 (2019)
Journal of Biomedical Science
Journal of Biomedical Science
The liver is controlled by several metabolic hormones, including thyroid hormone, and characteristically displays high lysosomal activity as well as metabolic stress-triggered autophagy, which is stringently regulated by the levels of hormones and me
Autor:
Meng-Han Wu, Hsiang-Cheng Chi, Ya-Hui Huang, Chau-Ting Yeh, I-Hsiao Chung, Kwang-Huei Lin, Chung-Ying Tsai, Ching-Ying Chen, Mei-Ling Cheng, Yang-Hsiang Lin
Publikováno v:
Hepatology. 67:188-203
Cancer cells display altered glucose metabolism characterized by a preference for aerobic glycolysis. The aerobic glycolytic phenotype of hepatocellular carcinoma (HCC) is often correlated with tumor progression and poorer clinical outcomes. However,
Autor:
Ya-Hui Huang, Sheng Ming Wu, Chau Ting Yeh, Chung-Ying Tsai, Cheng Pu Sun, Shen Liang Chen, Wen-Yu Chuang, Hsiang Cheng Chi, Ming Chieh Tsai, Kwang-Huei Lin
Publikováno v:
Autophagy. 12:2271-2285
Recent studies have demonstrated a critical association between disruption of cellular thyroid hormone (TH) signaling and the incidence of hepatocellular carcinoma (HCC), but the underlying mechanisms remain largely elusive. Here, we showed that disr
Autor:
Chung-Ying Tsai, Wen-Yu Chuang, Hsiang-Cheng Chi, Chau-Ting Yeh, Yang-Hsiang Lin, Meng-Han Wu, Kwang-Huei Lin, Ya-Hui Huang, I-Hsiao Chung, Ching-Ying Chen, Chia-Jung Yu
Publikováno v:
Endocrine-related cancer. 25(12)
Thyroid hormone (T3) and its receptor (TR) are involved in cancer progression. While deregulation of long non-coding RNA (lncRNA) expression has been detected in many tumor types, the mechanisms underlying specific involvement of lncRNAs in tumorigen
Autor:
Yang-Hsiang Lin, Ching-Ying Chen, Meng-Han Wu, Tina P. Lin, Kwang-Huei Lin, Sheng-Ming Wu, Chia-Jung Liao, Wei-Jan Chen, Hsiang-Cheng Chi, Chung-Ying Tsai, Ming-Ming Tsai, Yung-Hsin Yeh, Cheng Yi Chen, Ya-Hui Huang, Yi-Hsin Tseng, I-Hsiao Chung
Publikováno v:
Journal of Hepatology. 62:1328-1340
Background & Aims Thyroid hormone (T 3 ) and its receptor (TR) are involved in cell growth and cancer progression. Although deregulation of microRNA (miRNA) expression has been detected in many tumor types, the mechanisms underlying functional impair
Autor:
Hsiang Cheng Chi, Kwang-Huei Lin, Sheng Ming Wu, Chung-Ying Tsai, Wei Chun Chang, Ming Chieh Tsai, Yi Hsin Tseng, Ya-Hui Huang, Wei Jan Chen, Yang Hsiang Lin, Ya Ting Chang, Tzu-Kang Lin
Publikováno v:
Scientific Reports
Stathmin (STMN1), a recognized oncoprotein upregulated in various solid tumors, promotes microtubule disassembly and modulates tumor growth and migration activity. However, the mechanisms underlying the genetic regulation of STMN1 have yet to be eluc
Autor:
Yenlin Huang, Chung-Ying Tsai, Shen Liang Chen, Ming-Ming Tsai, Yang Hsiang Lin, Wen-Yu Chuang, Hsiang-Cheng Chi, Chien-Yuh Yeh, Kwang-Huei Lin, Syuan-Ling Lin
Publikováno v:
Oncogene. 36(37)
Infection by hepatitis B virus (HBV) accounts for 50-80% of hepatocellular carcinoma (HCC) development worldwide, in which the HBV-encoded X protein (HBx) has critical role in the induction of carcinogenesis. Several studies have shown that thyroid h
Autor:
Sheng-Ming, Wu, Syuan-Ling, Lin, Kang-Yun, Lee, Hsiao-Chi, Chuang, Po-Hao, Feng, Wan-Li, Cheng, Chia-Jung, Liao, Hsiang-Cheng, Chi, Yang-Hsiang, Lin, Chung-Ying, Tsai, Wei-Jan, Chen, Chau-Ting, Yeh, Kwang-Huei, Lin
Publikováno v:
International journal of cancer. 140(7)
NEK2 (NIMA-related expressed kinase 2) is a serine/threonine centrosomal kinase that acts as a critical regulator of centrosome structure and function. Aberrant NEK2 activities lead to failure in regulating centrosome duplication. NEK2 overexpression
Autor:
Chia-Jung Liao, Yin-Cheng Huang, Yi-Hsin Tseng, Shen Liang Chen, C. Y. Chen, Sheng-Ming Wu, Chien-Yuh Yeh, Ming-Ming Tsai, I-Hsiao Chung, Kwang-Huei Lin, Hsiang-Cheng Chi, Wei Jan Chen, Chung-Ying Tsai, Yang Hsiang Lin, Chen-Hsin Liao
Publikováno v:
Cell Death & Differentiation. 19:1802-1814
Although accumulating evidence has confirmed the important roles of thyroid hormone (T(3)) and its receptors (TRs) in tumor progression, the specific functions of TRs in carcinogenesis remain unclear. In the present study, tumor necrosis factor (TNF)
Autor:
Chen-Hsin Liao, Hsiang-Cheng Chi, I-Hsiao Chung, Chung-Ying Tsai, Cheng Yi Chen, Ming-Ming Tsai, Wei-Jan Chen, Kwang-Huei Lin, Yi-Hsin Tseng, Sheng-Ming Wu, Yang-Hsiang Lin, Chia-Jung Liao, Chau-Ting Yeh, Wan-Li Cheng, Ya-Hui Huang
Publikováno v:
Hepatology. 55:910-920
Thyroid hormone (T3) mediates cellular growth, development, and differentiation by binding to the nuclear thyroid hormone receptor (TR). Recent studies suggest that long-term hypothyroidism is associated with human hepatocellular carcinoma (HCC) inde