Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Crispin A"'
Autor:
Crispin Jenkinson, Ray Fitzpatrick, Chidiebere Hope Nwolise, Avinash Gupta, Rubeta N Matin, Pippa Corrie, Mark R. Middleton
Publikováno v:
Chronic Illness. 19:81-94
Peer reviewed: True
Funder: National Institute for Health Research (NIHR) Research for Patient Benefit (RfPB); Grant(s): Grant Reference Number: PB-PG-0815-20048
OBJECTIVE: A qualitative sub-study was carried out within a larger phase II fe
Funder: National Institute for Health Research (NIHR) Research for Patient Benefit (RfPB); Grant(s): Grant Reference Number: PB-PG-0815-20048
OBJECTIVE: A qualitative sub-study was carried out within a larger phase II fe
Autor:
John G. Edwards, Matthew Neilson, Davand Sharma, Fiona T. Thomson, Carol McCormick, Caroline Kelly, Euan J. Cameron, Seamus Grundy, Stephen R. L. Clark, Samantha Hinsley, David Breen, Angela Wright, Dipak Mukherjee, Crispin J. Miller, Rachel Ostroff, Alan Hart-Thomas, J Holme, Mohammed Munavvar, Ioannis Psallidas, Giles Cox, Holly Hall, Rakesh Panchal, Nick A Maskell, Rehan Naseer, Matthew Evison, Leigh Alexander, Laura Alexander, Mahendran Chetty, Alina Ionescu, S. Tsim, Elankumaran Paramasivam, Kevin G. Blyth, Ann Shaw, Douglas Grieve, Anthony J. Chalmers, C Daneshvar
Publikováno v:
Journal of Thoracic Oncology
Introduction:\ud Malignant pleural mesothelioma (MPM) is difficult to diagnose. An accurate blood biomarker could prompt specialist referral or be deployed in future screening. In earlier retrospective studies, SOMAscan proteomics (Somalogic, Boulder
Autor:
S. Brown, H. Clinch, Crispin T. Hiley, Gerard Walls, M. Qureshi, J. Hicks, S. Silverman, L. Magee, D. Johnston, L. Philipps, David Gilligan, Emma Barrett, Mary O'Brien, K. Blyth, Matthew Hatton, Fiona McDonald, Corinne Faivre-Finn, A. Cheng, M. Denholm, K. Moore, A. Mulla, Matthew Evison, Jonathan McAleese, A. Punjabi
Publikováno v:
Clinical Oncology. 33:e331-e338
The neutrophil-lymphocyte ratio (NLR) and the absolute lymphocyte count (ALC) have been proposed as prognostic markers in non-small cell lung cancer (NSCLC). The objective of this study was to examine the association of NLR/ALC before and after curat
Autor:
Hélène Mahenzi Mbembo, Mathieu Nkieri Matsho, Bruno Scherrer, Steven Lumeya Vuvu, Wilfried Mutombo Kalonji, Franck Botalema Bolengi, Olaf Valverde Mordt, Sonja Bernhard, Sophie Delhomme, Séverine Blesson, Antoine Tarral, Tim Mayala Malu, Clélia Bardonneau, Serge Kapongo Tshilumbwa, Dieudonné Mpoyi Muamba Nzambi, Felix Akwaso Masa, François Simon, Melchias Mukendi Ilunga, Crispin Lumbala, Digas Ngolo Tete, Nathalie Strub-Wourgaft, Victor Kande Betu Ku Mesu, Christian Mpia Moke, Junior Mudji E'kitiak
Publikováno v:
The Lancet. Global Health
The Lancet Global Health, Vol 9, Iss 7, Pp e999-e1008 (2021)
The Lancet Global Health, Vol 9, Iss 7, Pp e999-e1008 (2021)
Summary Background Staging and treatment of human African trypanosomiasis caused by Trypanosoma brucei gambiense (g-HAT) required lumbar puncture to assess cerebrospinal fluid (CSF) and intravenous drugs that cross the blood–brain barrier for late-
Autor:
James H. Flory, Dominique Guelce, Crispin Goytia, Jing Li, Jea Young Min, Al Mushlin, Jeremy Orloff, Victoria Mayer
Publikováno v:
Journal of general internal medicine.
Over 5 million patients in the United States have type 2 diabetes mellitus (T2D) with chronic kidney disease (CKD); antidiabetic drug selection for this population is complex and has important implications for outcomes.To better understand how provid
Autor:
Emily J. Kay, Karla Paterson, Carla Riera-Domingo, David Sumpton, J. Henry M. Däbritz, Saverio Tardito, Claudia Boldrini, Juan R. Hernandez-Fernaud, Dimitris Athineos, Sandeep Dhayade, Ekaterina Stepanova, Enio Gjerga, Lisa J. Neilson, Sergio Lilla, Ann Hedley, Grigorios Koulouras, Grace McGregor, Craig Jamieson, Radia Marie Johnson, Morag Park, Kristina Kirschner, Crispin Miller, Jurre J. Kamphorst, Fabricio Loayza-Puch, Julio Saez-Rodriguez, Massimiliano Mazzone, Karen Blyth, Michele Zagnoni, Sara Zanivan
Elevated production of collagen-rich extracellular matrix is a hallmark of cancer-associated fibroblasts (CAFs) and a central driver of cancer aggressiveness. Here we find that proline, a highly abundant amino acid in collagen proteins, is newly synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8907f37648075e95d3be5ff99db101
https://eprints.gla.ac.uk/274784/1/274784.pdf
https://eprints.gla.ac.uk/274784/1/274784.pdf
Autor:
Saba Ferdous, Charles Swanton, Francesca Chemi, Chang Sik Kim, Selvaraju Veeriah, Ged Brady, Sakshi Gulati, Deborah J. Burt, Mariam Jamal-Hanjani, Fiona H Blackhall, Daniel Slane-Tan, Nicholas McGranahan, Jackie Pierce, Marek Dynowski, Crispin J. Miller, Barbara Mesquita, Dominic G. Rothwell, Cong Zhou, David Allan Moore, Simon P. Pearce, Fabio Gomes, Philip A.J. Crosbie, Jonathan Tugwood, Nicolai Juul Birkbak, R. Shah, Gareth A. Wilson, Christopher Abbosh, Sophia Ward, Maise Al Bakir, Allan Hackshaw, Crispin T. Hiley, Caroline Dive, Dhruva Biswas, Yvonne Summers
Publikováno v:
Chemi, F, Rothwell, D G, McGranahan, N, Gulati, S, Abbosh, C, Pearce, S P, Zhou, C, Wilson, G A, Jamal-Hanjani, M, Birkbak, N, Pierce, J, Kim, C S, Ferdous, S, Burt, D J, Slane-Tan, D, Gomes, F, Moore, D, Shah, R, Al Bakir, M, Hiley, C, Veeriah, S, Summers, Y, Crosbie, P, Ward, S, Mesquita, B, Dynowski, M, Biswas, D, Tugwood, J, Blackhall, F, Miller, C, Hackshaw, A, Brady, G, Swanton, C, Dive, C & TRACERx Consortium 2019, ' Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse ', Nature Medicine, vol. 25, no. 10, pp. 1534-1539 . https://doi.org/10.1038/s41591-019-0593-1
TRACERx Consortium 2019, ' Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse ', Nature Medicine, vol. 25, no. 10, pp. 1534-1539 . https://doi.org/10.1038/s41591-019-0593-1
TRACERx Consortium 2019, ' Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse ', Nature Medicine, vol. 25, no. 10, pp. 1534-1539 . https://doi.org/10.1038/s41591-019-0593-1
Approximately 50% of patients with early-stage non-small-cell lung cancer (NSCLC) who undergo surgery with curative intent will relapse within 5 years1,2. Detection of circulating tumor cells (CTCs) at the time of surgery may represent a tool to iden
Autor:
Charles McDonald, John Napoli, Thomas J. Borody, Rupert W. Leong, Webber Chan, Peter H. Katelaris, Anil Keshava, Daniel A. Lemberg, Aviv Pudipeddi, Sudarshan Paramsothy, Viraj C. Kariyawasam, Crispin Corte, Robert Clancy, Cheng H Lee, Grace Chapman, Jeffrey Liu, James L. Cowlishaw
Publikováno v:
Medical Journal of Australia. 214:365-370
Objectives To determine the age-standardised prevalence of inflammatory bowel disease (IBD) in a metropolitan area of Sydney, with a focus on its prevalence among older people. Design, setting Population-based epidemiological study of people with IBD
Publikováno v:
Therapeutic Delivery. 11:733-753
Metformin was originally derived from a botanical ancestry and became the most prescribed, first-line therapy for Type 2 diabetes in most countries. In the last century, metformin was discovered twice for its antiglycemic properties in addition to it
Autor:
Celina Whalley, Charlotte Poxon, Gabriella L. Morley, Kasun Wanigasooriya, Lyndsey A Dunbar, Mark T. Drayson, Dee E McLoughlin, Saly Al-Taei, Mark I. Garvey, Beena Emmanuel, Golaleh McGinnell, Sian E Jossi, Megan Richter, Andrew D Beggs, Marisol Perez-Toledo, Joel D. Allen, Adam F. Cunningham, Eloise M Walker, Agnieszka E. Zielinska, Joanna Gray, Max Crispin, Joanna O'Neill, Erin L. Aldera, Adrian M Shields, David C. Wraith, Andrew Bosworth, Oliver J Pickles, Sian E Faustini, Claire Backhouse, Alex G. Richter, Daniel Ebanks, I. Michael Kidd, Danai Papakonstantinou, Yasunori Watanabe
Publikováno v:
Thorax
ObjectiveTo determine the rates of asymptomatic viral carriage and seroprevalence of SARS-CoV-2 antibodies in healthcare workers.DesignA cross-sectional study of asymptomatic healthcare workers undertaken on 24/25 April 2020.SettingUniversity Hospita