Zobrazeno 1 - 8
of 8
pro vyhledávání: '"551"'
Autor:
Alexander Quaas, Hakan Alakus, Max Kraemer, Arnulf H. Hoelscher, Christiane Bruns, Wolfgang Schröder, Heike Loeser, Reinhard Buettner, Thomas Zander, Philipp Lohneis, Florian Gebauer
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Journal of Immunology Research
Journal of Immunology Research
Background. Indoleamine 2,3-dioxygenase (IDO) is an interferon-inducible immune checkpoint expressed on tumor-infiltrating lymphocytes (TILs). IDO is known as a poor prognostic marker in esophageal squamous cell cancer, while a positive effect was sh
Autor:
Pikka Jokelainen, Anu Näreaho, Erkka Valo, Antti Sukura, Jere Lindén, Niina Airas, Sampsa Hautaniemi
Publikováno v:
Experimental Parasitology. 135:363-369
Trichinella spiralis causes a significantly higher parasite burden in rat muscle than Trichinella nativa. To assess whether the difference in infectivity is due to the early intestinal response, we analyzed gene expression changes in the rat jejunum
Autor:
Gregory S. Park, James S. Hodges, Paul Bangirana, Estela Shabani, Thomas Lavstsen, Weihua Guan, Gregory M. Vercellotti, Chandy C. John, Robert O. Opoka
Publikováno v:
Scientific Reports
Shabani, E, Opoka, R O, Bangirana, P, Park, G S, Vercellotti, G M, Guan, W, Hodges, J S, Lavstsen, T & John, C C 2016, ' The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria ', Scientific Reports, vol. 6, 27084 . https://doi.org/10.1038/srep27084
Shabani, E, Opoka, R O, Bangirana, P, Park, G S, Vercellotti, G M, Guan, W, Hodges, J S, Lavstsen, T & John, C C 2016, ' The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria ', Scientific Reports, vol. 6, 27084 . https://doi.org/10.1038/srep27084
The endothelial protein C receptor (EPCR) appears to play an important role in Plasmodium falciparum endothelial cell binding in severe malaria (SM). Despite consistent findings of elevated soluble EPCR (sEPCR) in other infectious diseases, field stu
Autor:
Giovanni Caocci, Giancarlo Serra, Roberto Littera, Simona Onali, S. Casu, Maria Cristina Pasetto, C. Balestrieri, Rosetta Scioscia, Sandro Orru, T. Zolfino, Luchino Chessa, L. Secci, M Arras, Lucia Barca, Gavino Faa, Maurizio Melis, F. Figorilli, Sara Lai, Giorgio La Nasa, S. Cappellini, M. Conti, M. Casale, Laura Matta, Carlo Carcassi, C. Salustro, Fausto Zamboni
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 1, p e0146086 (2016)
PLoS ONE, Vol 11, Iss 1, p e0146086 (2016)
Background Natural killer cells are involved in the complex mechanisms underlying autoimmune diseases but few studies have investigated their role in autoimmune hepatitis. Killer immunoglobulin-like receptors are key regulators of natural killer cell
Autor:
J. Tyson McDonald, Sebastien Benzekry, Philip Hahnfeldt, Lynn Hlatky, Lili Ma, Michael J. Peluso, Afshin Beheshti
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2015, 75 (6), pp.10. ⟨10.1158/0008-5472.CAN-14-1053⟩
Cancer Research, 2015, 75 (6), pp.10. ⟨10.1158/0008-5472.CAN-14-1053⟩
Cancer Research, American Association for Cancer Research, 2015, 75 (6), pp.10. ⟨10.1158/0008-5472.CAN-14-1053⟩
Cancer Research, 2015, 75 (6), pp.10. ⟨10.1158/0008-5472.CAN-14-1053⟩
Aging is the major determinant of cancer incidence, which, in turn, is likely dictated in large part by processes that influence the progression of early subclinical (occult) cancers. However, there is little understanding of how aging informs change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2d55727e44745e77629ea9763d3e81
https://europepmc.org/articles/PMC4397972/
https://europepmc.org/articles/PMC4397972/
Autor:
Alan A. Dombkowski, Larry H. Matherly, Yubin Ge, Jeffrey W. Taub, Yaddanapudi Ravindranath, David L. Becton, Katherine M. LaFiura, Ravikiran S. Yedidi, Gita Massey, Howard J. Weinstein, Steven Buck, Mark Stout, Dana Tatman
Publikováno v:
Blood. 107:1570-1581
Children with Down syndrome (DS) with acute megakaryocytic leukemia (AMkL) have very high survival rates compared with non-DS AMkL patients. Somatic mutations identified in the X-linked transcription factor gene, GATA1, in essentially all DS AMkL cas
Autor:
Venkatesha Basrur, Andrew G. Muntean, Lili Chen, Joel Bronstein, Tao Xu, Cailin Collins, Kojo S.J. Elenitoba-Johnson, Sung Soo Park, Honglai Zhang, Jingya Wang, Rork Kuick, Jay L. Hess, Kim Kyoung Ha, Jean François Rual
Publikováno v:
Blood. 124:3533-3533
HOXA9 helps maintain the balance between hematopoietic stem/progenitor cell self-renewal and myeloid/lymphoid cell differentiation in the bone marrow (BM). HOXA9 encodes a homeodomain-containing transcription factor, which mediates its function in co
Publikováno v:
Scopus-Elsevier
Cytokine signaling is negatively regulated by a set of SH2 domain-containing proteins, the Suppressors of Cytokine Signaling (SOCS) acting as intracellular modulators. Experimental evidence indicates that SOCS gene expression is induced by cytokines