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Publikováno v:
Nutr Neurosci
High-fat diets are linked with obesity and changes in dopamine neurotransmission. Mounting evidence shows that saturated fat impacts dopamine neurons and their terminal fields, but little is known about the effect a diet high in unsaturated fat has o
Publikováno v:
Nutritional Neuroscience. 25:2601-2615
BACKGROUND Obesity has been linked to behavioral and biochemical changes, such as reduced physical activity, dysregulated dopamine metabolism, and gene expression alterations in the brain. The impact of a continuous high-fat diet and resulting state
Autor:
Conner W. Wallace, Steve C. Fordahl
Publikováno v:
Nutrition Research Reviews. 35:236-251
The aim of this review is to explore how metabolic changes induced by diets high in saturated fat (HFD) affect nucleus accumbens (NAc) dopamine neurotransmission and food intake, and to explore how stress and inflammation influence this process. Rece
Autor:
Heather A. Emmons, Sarah A. Hutcherson, Steve C. Fordahl, Nari S. Beatty, Conner W. Wallace, Madison C. Loudermilt
Publikováno v:
Nutrients
Volume 13
Issue 7
Nutrients, Vol 13, Iss 2341, p 2341 (2021)
Volume 13
Issue 7
Nutrients, Vol 13, Iss 2341, p 2341 (2021)
Diet-induced obesity reduces dopaminergic neurotransmission in the nucleus accumbens (NAc), and stressful weight loss interventions could promote cravings for palatable foods high in fat and sugar that stimulate dopamine. Activation of κ-opioid rece