Zobrazeno 1 - 10
of 162 825
pro vyhledávání: ''
Publikováno v:
Antioxidantsredox signaling. 37(7-9)
SIGNIFICANCE Reactive oxygen species (ROS) contribute to multiple aspects of peripheral nervous system (PNS) biology ranging from physiological processes (e.g. axonal outgrowth and regeneration), to pathophysiology (e.g. nerve degeneration). Although
Autor:
Celeste Caruso Bavisotto, Claudia Campanella, Francesco Cappello, Fabio Bucchieri, Antonella Marino Gammazza
Publikováno v:
Seminars in Cancer Biology. 86:36-45
In cancer, human cells lose the ability to properly control the series of events that occur constantly during cell growth and division, including protein expression, stability, and dynamics. Heat shock proteins (Hsps) are key molecules in these event
Publikováno v:
Cold Spring Harb Perspect Med
Leukemias and lymphomas acquire the capacity for unrestrained cell growth and proliferation in conjunction with loss of responsiveness to molecular programs that promote terminal differentiation. Malignant cells generate the building blocks required
Autor:
Jae-Hyun Lee, Chang-Min Lee, Joyce H. Lee, Mun-Ock Kim, Jin Wook Park, Suchitra Kamle, Bedia Akosman, Erica L. Herzog, Xue Yan Peng, Jack A. Elias, Chun Geun Lee
Publikováno v:
Am J Respir Cell Mol Biol
RationalePulmonary fibrosis is a devastating lung disease with few therapeutic options. Chitinase 1 (CHIT1), an 18 glycosyl hydrolase family member, contributes to the pathogenesis of pulmonary fibrosis through regulation of Transforming Growth Facto
Autor:
Jian Wang, Zichao Feng, Zhaoyang Zhong, Qichao Qi, Wenjie Li, Jiwei Wang, Ning Yang, Qing Zhang, Bin Huang, Chen Qiu, Xiaofei Liu, Yaotian Hu, Anjing Chen, Wenxing Jin, Wenjing Zhou, Zhiyi Xue
Publikováno v:
Cell Cycle
Background: Nucleolar and spindle associated protein 1 (NUSAP1) is an indispensable mitotic regulator, which has been reported to be involved in the development, progression, and metastasis of several types of cancer. Here, we investigated the expres
Publikováno v:
Seminars in Cancer Biology. 85:123-154
The RAF-MEK-ERK signaling cascade is a well-characterized MAPK pathway involved in cell proliferation and survival. The three-layered MAPK signaling cascade is initiated upon RTK and RAS activation. Three RAF isoforms ARAF, BRAF and CRAF, and their d
Autor:
Wei Liu, Zhiqiang Yu, Zhi Chen, Kun Liu, Xiaomei Ye, Chaobo Huang, Dudu Wu, Kangrui Yuan, Yuyun Li
Publikováno v:
IEEE Transactions on NanoBioscience. 21:549-559
Lycorine-nanoparticles (LYC-NPs) were successfully synthesized using anti-solvent precipitation-freeze drying method, and characterized using transmission electron microscopy (TEM), particle size analysis and Fourier transform infrared spectroscopy (
Autor:
Paul Fernyhough, Eftekhar Eftekharpour
Publikováno v:
Antioxidants & Redox Signaling. 37:578-596
Significance. This review highlights the many intracellular processes generating reactive oxygen species (ROS) in the peripheral nervous system in the context of type 1 diabetes. The major sources ...
Autor:
Clark A. Bonham, Dharshan Sivaraj, Michael T. Longaker, Jagannath Padmanabhan, Kellen Chen, Dominic Henn, Derrick C. Wan, Michael Januszyk, Artem A. Trotsyuk, Geoffrey C. Gurtner, Michelle Griffin, Hudson Choi Kussie
Publikováno v:
Advances in Wound Care. 11:466-478
Objective: After injury, humans and other mammals heal by forming fibrotic scar tissue with diminished function, and this healing process involves the dynamic interplay between resident cells withi...
Autor:
Lauren Schaff, Christian Grommes
Publikováno v:
Blood. 140:971-979
Primary central nervous system lymphoma (PCNSL) is a rare extranodal lymphomatous malignancy that affects the brain, spinal cord, leptomeninges, or vitreoretinal space, without evidence of systemic involvement. The diagnosis of PCNSL requires a high