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Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-18
Brevilin A (BA), a sesquiterpene lactone isolated from Centipeda minima herb, has been identified to exhibit potent anticancer activity. However, the potential pharmacological effect and mechanism of BA in regulating endothelial cell (EC) angiogenesi
Autor:
Abdolreza Ardeshirylajimi, Zahrasadat Paknejad, Maryam Rezai Rad, Hanieh Nokhbatolfoghahaei, Arash Khojasteh
Publikováno v:
Current stem cell research & therapy
Introduction: It has been shown that mechanical forces can induce or promote osteogenic differentiation as well as remodeling of the new created bone tissues. To apply this characteristic in bone tissue engineering, it is important to know which mech
Publikováno v:
Cell Biology International. 46:2246-2256
Many patients with prostate cancer (PCa) cannot be diagnosed until an advanced stage, which make PCa become a large threat to human health. It is an urgent need to explore novel biomarkers for accurate diagnosis and targets for the effective treatmen
Autor:
Qianlei Zhao, Tingting Chen, Chao Ni, Yingying Hu, Yan Nan, Wei Lin, Yanli Liu, Feixia Zheng, Xulai Shi, Zhongdong Lin, Jianghu Zhu, Zhenlang Lin
Publikováno v:
ACS Chemical Neuroscience. 13:2897-2912
The blood-brain barrier (BBB) is an important physiological barrier of the human body contributing to maintaining brain homeostasis and normal function. Hypoxic-ischemic (HI)-related brain injury is one of the main causes of neonatal acute morbidity
Autor:
Chao Sun, Lei Wang, Dan-dan Du, Jian-bo Ji, Xiao-xia Yang, Bing-fang Yu, Peng-fei Shang, Xiu-Li Guo
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-19
Downregulated DSC2 involved in the metastasis of cancers. Unfortunately, its role on the development of gastric cancer (GC) and the potential mechanisms remain unclear. Bioinformatics analysis, Western blot, qRT-PCR, and immunohistochemistry were per
Autor:
Yan Wang, Shiyong Luo, Yuxuan Wang, Shengbang Yang, Zhitong Huang, Xuejin Zhu, Shanghua Cai, Qifeng Guo, Weide Zhong, Sihong Liu
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-16
The aim of this study is to elucidate molecular mechanism by which E1A-like inhibitor of differentiation 3 (EID3) promotes cancer stem cell-like phenotypes in osteosarcoma. Overexpression of EID3 in osteosarcoma cells generated more spherical clones,
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-11
Rosin derivatives such as dehydroabietic acid and dehydroabietic amine belonging to diterpenoids have similar structure with androgen that inhibited the occurrence and development of prostate cancer. In this study, the effects and possible mechanism
Autor:
Zheng Zhou, Yaokun Dong, Na Li, Mengyue Niu, Shisheng Wang, Yuanzhang Zhou, Zhaolin Sun, Peng Chu, Zeyao Tang
Publikováno v:
Cell Biology International. 46:1801-1813
Oleanolic acid (OA) and its derivatives show potent anticancer function. Pancreatic cancer (PC) is the fourth core motive of cancer-related deaths worldwide. Epidermal growth factor receptor (EGFR) has been implicated in PC and has been validated as
Publikováno v:
Current Protein & Peptide Science. 23:535-547
Abstract: Acute myocardial infarction (AMI) is a threat to human life and physical health worldwide. Timely reperfusion is very important to limit infarct size and protect ischemic myocardium. Unfortunately, it has also caused severer myocardial dama
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 58:539-548
Mesenchymal stem cells can be differentiated into tissue-specific cells. MicroRNAs (miRNAs) regulate the translation of mRNAs involved in the growth and development of a variety of cells, including primordial germ cells (PGCs). This study evaluated m