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Publikováno v:
Biochemical and Biophysical Research Communications. 618:100-106
Regeneration of periodontal hard tissues damaged by Porphyromonas gingivalis (P. gingivalis) is essential for tooth stability and dental health. Irisin, a myokine secreted by skeletal muscle, is involved in different biological processes, such as myo
MicroRNAs (miRNAs) crucially modulate fundamental biologic processes such as angiogenesis. In the present study, we focused on the molecular function of miRNA-370-3p (miR-370) in regulating the angiogenic activity of endothelial cells (ECs). Transfec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21aa23e93d80c91eef5d69c1fda31721
Autor:
Ming Qiu, Huanyu Shu, Lu Li, Yejiao Shen, Yunfan Tian, Yue Ji, Wei Sun, Yan Lu, Xiangqing Kong
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-15
Interleukin 10 (IL-10) is a probable anti-inflammatory factor that can attenuate hypertrophic remodelling caused by overloaded pressure and improve cardiac function. In this study, IL-10 was decreased in both the plasma of hypertensive patients and t
Publikováno v:
Stem Cells, 40(2), 165-174. Wiley
Controlling stem cell fate is the cornerstone of regenerative medicine. Cadherins have an important role in cell fate commitment and the function of cadherin-11 in the regulation of differentiation in human mesenchymal stem cells (hMSCs) has recently
Autor:
Yue, Kang, Wenye, Pei
Publikováno v:
Journal of Molecular Histology. 53:379-394
Autologous bone transplantation which is a common treatment method for bone defects needs a large quantity of bone cells. In order to develop new treatments to regenerating bone tissues, this research aimed at identifying the key genes and finding th
Autor:
Oscar Palomares, Alba Angelina, Beate Rückert, Mar Martín-Fontecha, Mario Pérez-Diego, Cezmi A. Akdis, Jacobo López-Abente, Ivan Nombela, Mübeccel Akdis
Publikováno v:
Mucosal Immunology
E-Prints Complutense. Archivo Institucional de la UCM
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E-Prints Complutense. Archivo Institucional de la UCM
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The generation of functional regulatory T cells (Tregs) is essential to keep tissue homeostasis and restore healthy immune responses in many biological and inflammatory contexts. Cannabinoids have been pointed out as potential therapeutic tools for s
Autor:
Albericio, Guillermo, Aguilar, Susana, Torán, Jose Luis, Yañez, Rosa, López, Juan Antonio, Vázquez, Jesús, Mora, Carmen, Bernad, Antonio
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Scientific Reports
Scientific Reports
Clinical trials evaluating cardiac progenitor cells (CPC) demonstrated feasibility and safety, but no clear functional benefits. Therefore a deeper understanding of CPC biology is warranted to inform strategies capable to enhance their therapeutic po
Autor:
Shenghua Zhou, Yuting Cui, Hao Yin, Zhihan Tang, Yu Gui, Shi Tai, Darrell D. Belke, Binjie Yan, Xi-Long Zheng, Yanan Guo, Juan Peng
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42:67-86
Objective: PCSK9 (proprotein convertase subtilisin/kexin type 9) plays a critical role in cholesterol metabolism via the PCSK9–LDLR (low-density lipoprotein receptor) axis in the liver; however, evidence indicates that PCSK9 directly contributes to
Autor:
Hassiba Bouktit, C. Méni, Marine Madrange, Elisa Bayard, Laurent Frenzel, Michel Arock, Olivier Hermine, Christine Bodemer, Leila Maouche-Chretien, Sylvie Fraitag, Ulrich Rüther, Margot Tissandier, Laura Polivka, Anne-Florence Collange, Julien Rossignol, Mélanie Parisot, Christina Gougoula, Rachel Rignault, Smail Hadj-Rabia, Julie Bruneau, Brigitte Bader-Meunier, Nicolas Cagnard, Cristina Bulai Livideanu, Veronique Parietti, Erinn Soucie, Camille Laurent, Ludovic Lhermitte, Patrice Dubreuil, Danielle Canioni, Mélanie Féroul
Publikováno v:
Blood. 138:2396-2407
Mastocytosis is a heterogeneous disease characterized by an abnormal accumulation of mast cells (MCs) in 1 or several organs. Although a somatic KIT D816V mutation is detected in ∼85% of patients, attempts to demonstrate its oncogenic effect alone
Publikováno v:
Bioengineered, Vol 12, Iss 2, Pp 10878-10890 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Retinopathy of Prematurity (ROP), a type of retinal neovascularization in premature infants, has become a serious problem that drastically affects the quality of life of premature infants. ROP is associated with angiogenesis and neovascularization. H