Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Pedro R. Lowenstein"'
Autor:
María Perazzo, Carlos Vigliano, Jorge Cáneva, Melany Berdiñas Anfuso, Juan Calderón Soriano, Alejandra Vigliano, Hugo Paladini, Francisco Klein, Victoria Ruiz, Juan Ossés, Pedro R. Lowenstein
Publikováno v:
Virchows Archiv
We present results from clinical, radiologic, gas exchange, lung mechanics, and fibre-optic bronchoscopy-guided transbronchial biopsies in a case of acute respiratory failure due to SARS-CoV-2 (Covid-19). This report highlights the pulmonary, immunol
Autor:
Melissa Cadena, Erkki Ruoslahti, Robert Doherty, Padma Kadiyala, Maria G. Castro, Samer Habeel, Joerg Lahann, Jason V. Gregory, Pedro R. Lowenstein
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Glioblastoma (GBM), the most aggressive form of brain cancer, has witnessed very little clinical progress over the last decades, in part, due to the absence of effective drug delivery strategies. Intravenous injection is the least invasive drug deliv
Autor:
Maria B. Garcia-Fabiani, Santiago Haase, Andrea Comba, Stephen Carney, Brandon McClellan, Kaushik Banerjee, Mahmoud S. Alghamri, Faisal Syed, Padma Kadiyala, Felipe J. Nunez, Marianela Candolfi, Antonela Asad, Nazareno Gonzalez, Marisa E. Aikins, Anna Schwendeman, James J. Moon, Pedro R. Lowenstein, Maria G. Castro
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
High grade gliomas are malignant brain tumors that arise in the central nervous system, in patients of all ages. Currently, the standard of care, entailing surgery and chemo radiation, exhibits a survival rate of 14-17 months. Thus, there is an urgen
Autor:
Mahmoud S. Alghamri, Brandon L. McClellan, Margaret S. Hartlage, Santiago Haase, Syed Mohd Faisal, Rohit Thalla, Ali Dabaja, Kaushik Banerjee, Stephen V. Carney, Anzar A. Mujeeb, Michael R. Olin, James J. Moon, Anna Schwendeman, Pedro R. Lowenstein, Maria G. Castro
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
Gliomas are one of the most lethal types of cancers accounting for ∼80% of all central nervous system (CNS) primary malignancies. Among gliomas, glioblastomas (GBM) are the most aggressive, characterized by a median patient survival of fewer than 1
Publikováno v:
Molecular & Cellular Oncology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Glioblastoma is an aggressive brain tumor with poor prognosis. The brain is protected by the blood–brain barrier, which precludes transport of chemotherapeutics. We developed nanoparticles that achieve delivery of small-interfering RNA against Stat
Publikováno v:
Oncotarget
Diffuse intrinsic pontine glioma (DIPG) is a rare brainstem tumor which carries a dismal prognosis. To date. there are no effective treatments for DIPG. Transcriptomic studies have shown that DIPGs have a distinct profile compared to hemispheric high
Autor:
Kaushik Banerjee, Felipe J. Núñez, Santiago Haase, Brandon L. McClellan, Syed M. Faisal, Stephen V. Carney, Jin Yu, Mahmoud S. Alghamri, Antonela S. Asad, Alejandro J. Nicola Candia, Maria Luisa Varela, Marianela Candolfi, Pedro R. Lowenstein, Maria G. Castro
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in the adult population and it carries a dismal prognosis. Inefficient drug delivery across the blood brain barrier (BBB), an immunosuppressive tumor microenvironment (TME) and
Tumor mutational burden predicts survival in patients with low-grade gliomas expressing mutated IDH1
Autor:
Rohit Thalla, Mahmoud S. Alghamri, Ali Dabaja, Maria G. Castro, Lili Zhao, Ayman Taher, Ruthvik Avvari, Pedro R. Lowenstein, Peter J. Ulintz
Publikováno v:
Neuro-oncology Advances
Background Gliomas are the most common primary brain tumors. High-Grade Gliomas have a median survival (MS) of 18 months, while Low-Grade Gliomas (LGGs) have an MS of approximately 7.3 years. Seventy-six percent of patients with LGG express mutated i
Autor:
Stephen Carney, Andrea Comba, Maria B. Garcia-Fabiani, Alejandro Javier Nicola Candia, Ava Mauser, Anna Schwendeman, Maria Ventosa, Marianela Candolfi, Lindsay Scheetz, Pedro R. Lowenstein, Mahmoud S. Alghamri, Padma Kadiyala, James J. Moon, Joerg Lahann, Maria G. Castro, Syed M Faisal
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Gliomas are infiltrating brain tumors associated with high morbidity and mortality. Current standard of care includes radiation, chemotherapy and surgical resection. Today, survival rates for malignant glioma patients remain dismal and unchanged for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb1626dafe0a01d701a6f662b67b397
https://www.tandfonline.com/doi/full/10.1080/13543784.2020.1768528
https://www.tandfonline.com/doi/full/10.1080/13543784.2020.1768528
Autor:
Alireza Hassani Najafabadi, Xiaoqi Sun, Sejin Son, Padma Kadiyala, Lindsay Scheetz, Anna Schwendeman, Pedro R. Lowenstein, James J. Moon, Marisa E. Aikins, Maria G. Castro
Publikováno v:
Clin Cancer Res
Purpose: Gliomas are brain tumors with dismal prognoses. The standard-of-care treatments for gliomas include surgical resection, radiation, and temozolomide administration; however, they have been ineffective in providing significant increases in med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8903c868986a6447b69e26304c9f23
https://europepmc.org/articles/PMC7442596/
https://europepmc.org/articles/PMC7442596/