Zobrazeno 1 - 6
of 6
pro vyhledávání: '"59"'
Autor:
Mauro D'Amato, Nicholas A. Kennedy, Anette Ocklind, Rahul Kalla, Alex Adams, Dirk Repsilber, Fernando Gomollón, Nicholas T. Ventham, Petr Ricanek, Jonas Christoffer Lindstrøm, Daniel Bergemalm, Fredrik Hjelm, Jonas Halfvarson, Jack Satsangi, Gwo-Tzer Ho, Cecilia Petren, Marie J. Pierik, Simen Vatn, Morten H. Vatn, Johan D. Söderholm, Christine Olbjørn, Jørgen Jahnsen
Publikováno v:
Journal of Crohn's & Colitis, 15(5), 699-708. Oxford University Press
Background Success in personalized medicine in complex disease is critically dependent on biomarker discovery. We profiled serum proteins using a novel proximity extension assay [PEA] to identify diagnostic and prognostic biomarkers in inflammatory b
Autor:
Leo McCluskey, Pilar Hernandez-Con, Xuemei Huang, Defne A. Amado, Michelle E. Fullard, Richard B. Dewey, Marijan Posavi, John Q. Trojanowski, Maria Diaz-Ortiz, Benjamine Liu, Daniel Weintraub, Andrew Siderowf, Jacqueline Rick, Alice Chen-Plotkin, Christine R. Swanson, R. Tyler Skrinak
Publikováno v:
PLoS Medicine, Vol 16, Iss 10, p e1002931 (2019)
PLoS Medicine
PLoS Medicine
Background Parkinson’s disease (PD) is a progressive neurodegenerative disease affecting about 5 million people worldwide with no disease-modifying therapies. We sought blood-based biomarkers in order to provide molecular characterization of indivi
Autor:
Katharina Fink, Carl Hamsten, Sahl Khalid Bedri, Anna Glaser, Ali Manouchehrinia, Jan Hillert, Tomas Olsson, Burcu Ayoglu, Hans Grönlund, Ola Nilsson, Anna Månberg, Peter Nilsson
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217208 (2019)
PLoS ONE
PLoS ONE
Multiple sclerosis (MS) treatment options have improved significantly over the past decades, but the consequences of MS can still be devastating and the needs for monitoring treatment surveillance are considerable. In the current study we used affini
Autor:
Xiuzhong Zheng, Saakshi Khattri, Emma Guttman-Yassky, Yeriel Estrada, Tom C. Chan, Patrick M. Brunner, James G. Krueger, Juana Gonzalez, Annunziata Dattola, Helen He, Huei-Chi Wen, Kunal Malik, Mayte Suárez-Fariñas
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
Beyond classic "allergic"/atopic comorbidities, atopic dermatitis (AD) emerges as systemic disease with increased cardiovascular risk. To better define serum inflammatory and cardiovascular risk proteins, we used an OLINK high-throughput proteomic as
Autor:
Lei Zhu, Zhanguo Li, Rulin Jia, Xiaozhen Zhao, Y. Cheng, Yuling Chen, Cibo Huang, Xiaolin Sun, Haiteng Deng, Yuhui Li
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199047 (2018)
PLoS ONE
PLoS ONE
Background Behcet's disease (BD) is a chronic, multisystem-involved vasculitis and its pathogenesis remains elusive. No specific serological markers for BD diagnosis have been established. Identification of novel diagnostic biomarkers will be helpful
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170741 (2017)
PLoS ONE
PLoS ONE
Idiopathic pulmonary fibrosis (IPF) is a gradual lung disease with a survival of less than 5 years post-diagnosis for most patients. Poor molecular description of IPF has led to unsatisfactory interpretation of the pathogenesis of this disease, resul