Zobrazeno 1 - 10
of 12
pro vyhledávání: '"59"'
Autor:
Mauro D'Amato, Nicholas A. Kennedy, Anette Ocklind, Rahul Kalla, Alex Adams, Dirk Repsilber, Fernando Gomollón, Nicholas T. Ventham, Petr Ricanek, Jonas Christoffer Lindstrøm, Daniel Bergemalm, Fredrik Hjelm, Jonas Halfvarson, Jack Satsangi, Gwo-Tzer Ho, Cecilia Petren, Marie J. Pierik, Simen Vatn, Morten H. Vatn, Johan D. Söderholm, Christine Olbjørn, Jørgen Jahnsen
Publikováno v:
Journal of Crohn's & Colitis, 15(5), 699-708. Oxford University Press
Background Success in personalized medicine in complex disease is critically dependent on biomarker discovery. We profiled serum proteins using a novel proximity extension assay [PEA] to identify diagnostic and prognostic biomarkers in inflammatory b
Autor:
Magnus Gisslén, Nicholas J. Ashton, Richard Dobson, Henrik Zetterberg, Aylin Yilmaz, Lars-Magnus Andersson, Kaj Blennow, Hamel Patel
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
The recent SARS-CoV-2 pandemic manifests itself as a mild respiratory tract infection in the majority of individuals leading to COVID-19 disease. However, in some infected individuals, this can progress to severe pneumonia and acute respiratory distr
Autor:
Xuejuan Gao, Hong-Ling Jia, Qi-Fang Song, Xiaoqiong Gu, Li Zhang, Ping Huang, Jing-Jie Jin, Zhou-Ping Wang, Xiao-Fei Xie
Publikováno v:
Cardiology in the Young. 27:1786-1796
BackgroundKawasaki disease, which is characterised by systemic vasculitides accompanied by acute fever, is regularly treated by intravenous immunoglobulin to avoid lesion formation in the coronary artery; however, the mechanism of intravenous immunog
Autor:
MeiHwa Tanielle Bench Alvarez, John S. K. Kauwe, Frederick Rohlfing, Jesse Cobell, Jackson King, Sydney A Young, Swati Anand, Dipti Jigar Shah, W. Evan Johnson, Steven W. Graves
Publikováno v:
Journal of Alzheimer's Disease. 49:317-327
Background: Alzheimer’s disease (AD) remains challenging to diagnose, especially early disease. Having serum AD biomarkers would be of significant interest both in the clinical setting and in drug development efforts. Objective: We applied a novel
Autor:
Christopher J. O'Donnell, Paul Courchesne, Pieter Muntendam, Caroline S. Fox, Martin G. Larson, Aram Adourian, Shih-Jen Hwang, Subha Subramanian, Daniel Levy, Peter Juhasz, Neal Gordon, Xiaoyan Yin
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34:939-945
Objective— Incorporation of novel plasma protein biomarkers may improve current models for prediction of atherosclerotic cardiovascular disease (ASCVD) risk. Approach and Results— We used discovery mass spectrometry (MS) to determine plasma conce
Publikováno v:
Experimental Eye Research. 108:110-119
Proliferative diabetic retinopathy (PDR) is a serious microangiopathic complication of diabetes mellitus and a major cause of blindness in working-age adults. Diabetes-induced alterations in the vitreous protein composition in diabetic patients with
Autor:
Jochen Metzger, William Mullen, Heiner V. Groesdonk, Angelique Stalmach, Matthias Klingele, Holger Husi, Stefan Herget-Rosenthal, Harald Mischak
Publikováno v:
Critical Care
Background Acute kidney injury (AKI) is a prominent problem in hospitalized patients and associated with increased morbidity and mortality. Clinical medicine is currently hampered by the lack of accurate and early biomarkers for diagnosis of AKI and
Autor:
Dimitrios, Farmakis, Thomas, Koeck, William, Mullen, John, Parissis, Bill D, Gogas, Maria, Nikolaou, John, Lekakis, Harald, Mischak, Gerasimos, Filippatos
Publikováno v:
European journal of heart failure. 18(7)
Urine proteome analysis (UPA) has already provided accurate discriminatory patterns of urinary peptides for renal disease, coronary artery disease, and asymptomatic LV diastolic dysfunction. UPA has now been used to characterize a discriminatory pept
Invasive candidiasis (IC) adds significantly to the morbidity and mortality of non-neutropenic patients if not diagnosed and treated early. To uncover serologic biomarkers that alone or in combination could reliably detect IC in this population, IgG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f4eb3c0feed0eb9f6d2cd3f0a4a521
https://eprints.ucm.es/31263/
https://eprints.ucm.es/31263/
Autor:
Richard S Finkel, Thomas O Crawford, Kathryn J Swoboda, Petra Kaufmann, Peter Juhasz, Xiaohong Li, Yu Guo, Rebecca H Li, Felicia Trachtenberg, Suzanne J Forrest, Dione T Kobayashi, Karen S Chen, Cynthia L Joyce, Thomas Plasterer, Pilot Study of Biomarkers for Spinal Muscular Atrophy Trial Group
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35462 (2012)
PLoS ONE
PLoS ONE
Background Spinal Muscular Atrophy (SMA) is a neurodegenerative motor neuron disorder resulting from a homozygous mutation of the survival of motor neuron 1 (SMN1) gene. The gene product, SMN protein, functions in RNA biosynthesis in all tissues. In